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Open AccessJournal ArticleDOI

Large-Vessel Stroke as a Presenting Feature of Covid-19 in the Young.

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TLDR
Five patients younger than 50 years of age with large-vessel stroke and Covid-19 infection presented to a health system in New York City over a 2-week period with signs of stroke and infection.
Abstract
Stroke in Young Patients with Covid-19 Five patients younger than 50 years of age with large-vessel stroke and Covid-19 infection presented to a health system in New York City over a 2-week period....

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Citations
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Inflammation at the crossroads of COVID-19, cognitive deficits and depression

TL;DR: In this paper , the authors reviewed evidence indicating that COVID-19 is associated with neuroinflammation, along with blood-brain barrier dysfunction, and found that patients with pre-existing cognitive and neuropsychiatric deficits show worse outcomes upon infection by SARS-CoV-2 and, conversely, COVID19 survivors may be at increased risk of developing dementia and mood disorders.
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A clinical primer for the expected and potential post-COVID-19 syndromes

TL;DR: In late 2019, a novel coronavirus SARS-CoV-2 (COVID-19) spread unchecked across the world's population as mentioned in this paper, with tens of millions infected, the long-term consequences of COVID-2019 infection will be a major health care focus for years after the contagion subsides.
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Echocardiographic Manifestations in COVID-19: A Review.

TL;DR: In this article, a review summarises these findings and discusses the possible mechanisms involved in patients with SARS-CoV-2 with echocardiography abnormalities and recommends using smaller portable equipment.
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Neurovascular Complications in COVID-19 Infection: Case Series.

TL;DR: A series of 10 hospitalized patients with confirmed coronavirus 2019 infections who developed severe neurovascular complications are presented and the possible reasons for these findings and their relationship to the novel Severe Acute Respiratory Syndrome coronav virus 2 infection are discussed.
References
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Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study.

TL;DR: Wang et al. as discussed by the authors used univariable and multivariable logistic regression methods to explore the risk factors associated with in-hospital death, including older age, high SOFA score and d-dimer greater than 1 μg/mL.
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Large artery ischaemic stroke in severe acute respiratory syndrome (SARS).

TL;DR: It is believed that increased vigilance against stroke and other thrombotic complications among critically-ill SARS patients in future outbreaks is needed, especially if treatment such as intravenous immunoglobulin, that increases pro-thrombosis tendency, is contemplated.
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Erythropoietin as candidate for supportive treatment of severe COVID-19.

TL;DR: Evidence that supports the use of human recombinant erythropoietin (EPO) for ameliorating course and outcome of seriously ill COVID-19 patients is recap here and the research design for a double-blind placebo-controlled randomized clinical trial including severely affected patients is planned to start shortly.
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Revisiting the Protein C Pathway: An Opportunity for Adjunctive Intervention in COVID-19?

TL;DR: The objective of this study was to establish a baseline for the evaluation of the Recombinant Human Activated Protein C Worldwide Evaluation in Severe Sepsis.
Journal ArticleDOI

COVID-19-associated pulmonary and cerebral thromboembolic disease

TL;DR: A case of a 79-year-old woman that presented with stroke and was found to have COVID-19 pneumonia and concomitant large burden pulmonary arterial clot is reported.
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