Large-Vessel Stroke as a Presenting Feature of Covid-19 in the Young.
Thomas J Oxley,J Mocco,Shahram Majidi,Christopher P. Kellner,Hazem Shoirah,I. Paul Singh,Reade De Leacy,Tomoyoshi Shigematsu,Travis R. Ladner,Kurt A. Yaeger,Maryna Skliut,Jesse Weinberger,Neha S. Dangayach,Joshua B. Bederson,Stanley Tuhrim,Johanna T Fifi +15 more
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Five patients younger than 50 years of age with large-vessel stroke and Covid-19 infection presented to a health system in New York City over a 2-week period with signs of stroke and infection.Abstract:
Stroke in Young Patients with Covid-19 Five patients younger than 50 years of age with large-vessel stroke and Covid-19 infection presented to a health system in New York City over a 2-week period....read more
Citations
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Impact of the Burden of COVID-19 in Italy: Results of Disability-Adjusted Life Years (DALYs) and Productivity Loss.
Mario Cesare Nurchis,Domenico Pascucci,M Sapienza,Leonardo Villani,Floriana D'Ambrosio,Francesco Castrini,Maria Lucia Specchia,Patrizia Laurenti,Gianfranco Damiani +8 more
TL;DR: The socio-economic burden of COVID-19 pandemic in Italy through the estimation of Disability-Adjusted Life Years (DALYs) and productivity loss was around EUR 100 million, based on data from official governmental sources collected since the inception of epidemic.
Journal ArticleDOI
Hypertension and related diseases in the era of COVID-19: a report from the Japanese Society of Hypertension Task Force on COVID-19.
Shigeru Shibata,Hisatomi Arima,Kei Asayama,Satoshi Hoshide,Atsuhiro Ichihara,Toshihiko Ishimitsu,Kazuomi Kario,Takuya Kishi,Masaki Mogi,Akira Nishiyama,Mitsuru Ohishi,Takayoshi Ohkubo,Kouichi Tamura,Masami Tanaka,Eiichiro Yamamoto,Koichi Yamamoto,Hiroshi Itoh +16 more
TL;DR: The present review critically evaluates the existing evidence for the epidemiological association between COVID-19 and hypertension, and summarizes the current knowledge regarding the pathophysiology of SARS-CoV-2 infection with an emphasis on ACE2, the cardiovascular system, and the kidney.
Journal ArticleDOI
UK-Wide Surveillance of Neurological and Neuropsychiatric Complications of COVID-19: The First 153 Patients
Varatharaj, Aravinthan, Thomas, Naomi, Ellul, Mark, Davies, Nicholas W. S.,Pollak, Tom, Tenorio, E. L.,Benedict D Michael,Benedict D Michael +3 more
TL;DR: The objective of this study was to establish a central nervous system injury registry for COVID-19 patients with known neurological complications and to assess the need for further research into these complications.
Posted ContentDOI
Olfactory transmucosal SARS-CoV-2 invasion as port of Central Nervous System entry in COVID-19 patients
Jenny Meinhardt,Josefine Radke,Carsten Dittmayer,Ronja Mothes,Jonas Franz,Michael Laue,Julia Schneider,Sebastian Brünink,Olga Hassan,Werner Stenzel,Marc Windgassen,Larissa Rößler,Hans-Hilmar Goebel,Hubert Martin,Andreas Nitsche,Walter J. Schulz-Schaeffer,Samy Hakroush,Martin Sebastian Winkler,Björn Tampe,Sefer Elezkurtaj,David Horst,Lars Oesterhelweg,Michael Tsokos,Barbara Ingold Heppner,Christine Stadelmann,Christian Drosten,Victor M. Corman,Helena Radbruch,Frank L. Heppner +28 more
TL;DR: By precisely investigating and anatomically mapping oro- and pharyngeal regions and brains of 32 patients dying from COVID-19, CNS infarction due to cerebral thromboembolism is described, and SARS-CoV-2 neurotropism is demonstrated.
Journal ArticleDOI
Masked education? The benefits and burdens of wearing face masks in schools during the current Corona pandemic.
TL;DR: The benefits and burdens of face masks in schools should be seriously considered and made obvious and clear to teachers and students and the school's specific situation must inform any decision regarding face mask use.
References
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Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study.
Fei Zhou,Ting Yu,Ronghui Du,Guohui Fan,Ying Liu,Zhibo Liu,Jie Xiang,Yeming Wang,Bin Song,Xiaoying Gu,Xiaoying Gu,Lulu Guan,Yuan Wei,Li Hui,Xudong Wu,Jiuyang Xu,Shengjin Tu,Yi Zhang,Hua Chen,Bin Cao +19 more
TL;DR: Wang et al. as discussed by the authors used univariable and multivariable logistic regression methods to explore the risk factors associated with in-hospital death, including older age, high SOFA score and d-dimer greater than 1 μg/mL.
Journal ArticleDOI
Large artery ischaemic stroke in severe acute respiratory syndrome (SARS).
T. Umapathi,Ai Ching Kor,Narayanaswamy Venketasubramanian,C. C. Tchoyoson Lim,Boon Chuan Pang,Tseng Tsai Yeo,Cheng Chuan Lee,Poh Lian Lim,Poh Lian Lim,Kuperan Ponnudurai,Khoon Leong Chuah,Puay Hoon Tan,Dessmon Y.H. Tai,Sze Peng Brenda Ang +13 more
TL;DR: It is believed that increased vigilance against stroke and other thrombotic complications among critically-ill SARS patients in future outbreaks is needed, especially if treatment such as intravenous immunoglobulin, that increases pro-thrombosis tendency, is contemplated.
Journal ArticleDOI
Erythropoietin as candidate for supportive treatment of severe COVID-19.
Hannelore Ehrenreich,Karin Weissenborn,Martin Begemann,Martin Begemann,Markus Busch,Eduard Vieta,Kamilla W. Miskowiak +6 more
TL;DR: Evidence that supports the use of human recombinant erythropoietin (EPO) for ameliorating course and outcome of seriously ill COVID-19 patients is recap here and the research design for a double-blind placebo-controlled randomized clinical trial including severely affected patients is planned to start shortly.
Journal ArticleDOI
Revisiting the Protein C Pathway: An Opportunity for Adjunctive Intervention in COVID-19?
TL;DR: The objective of this study was to establish a baseline for the evaluation of the Recombinant Human Activated Protein C Worldwide Evaluation in Severe Sepsis.
Journal ArticleDOI
COVID-19-associated pulmonary and cerebral thromboembolic disease
TL;DR: A case of a 79-year-old woman that presented with stroke and was found to have COVID-19 pneumonia and concomitant large burden pulmonary arterial clot is reported.
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