Large-Vessel Stroke as a Presenting Feature of Covid-19 in the Young.
Thomas J Oxley,J Mocco,Shahram Majidi,Christopher P. Kellner,Hazem Shoirah,I. Paul Singh,Reade De Leacy,Tomoyoshi Shigematsu,Travis R. Ladner,Kurt A. Yaeger,Maryna Skliut,Jesse Weinberger,Neha S. Dangayach,Joshua B. Bederson,Stanley Tuhrim,Johanna T Fifi +15 more
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Five patients younger than 50 years of age with large-vessel stroke and Covid-19 infection presented to a health system in New York City over a 2-week period with signs of stroke and infection.Abstract:
Stroke in Young Patients with Covid-19 Five patients younger than 50 years of age with large-vessel stroke and Covid-19 infection presented to a health system in New York City over a 2-week period....read more
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Severe COVID-19-related encephalitis can respond to immunotherapy.
Albert Cao,Benjamin Rohaut,Loïc Le Guennec,Samir Saheb,Clémence Marois,Victor Altmayer,Vincent T Carpentier,Safaa Nemlaghi,Marie Soulie,Quentin Morlon,Bryan Berthet-Delteil,Alexandre Bleibtreu,Mathieu Raux,Nicolas Weiss,Sophie Demeret +14 more
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Can symptoms of anosmia and dysgeusia be diagnostic for COVID-19?
TL;DR: This work aimed to investigate the diagnostic value of symptoms of anosmia and dysgeusia for COVID‐19, a potential neurological manifestation of coronavirus‐2019.
Journal ArticleDOI
Cytokine Storm in COVID-19 Patients, Its Impact on Organs and Potential Treatment by QTY Code-Designed Detergent-Free Chemokine Receptors
TL;DR: The novel coronavirus gains entry into humans by targeting the ACE2 receptor that found on lung cells, which leads to hyperinflammation, forcing the immune cells to destroy healthy cells, and this leads to cytokine storms in COVID-19 patients.
Posted Content
An artificial intelligence system for predicting the deterioration of COVID-19 patients in the emergency department
Farah E. Shamout,Yiqiu Shen,Nan Wu,Aakash Kaku,Jungkyu Park,Taro Makino,Taro Makino,Stanisław Jastrzębski,Stanisław Jastrzębski,Jan Witowski,Duo Wang,Ben Zhang,Siddhant Dogra,Meng Cao,Narges Razavian,Narges Razavian,David Kudlowitz,Lea Azour,William Moore,Yvonne W. Lui,Yindalon Aphinyanaphongs,Carlos Fernandez-Granda,Krzysztof J. Geras +22 more
TL;DR: The findings demonstrate the potential of the proposed system for assisting front-line physicians in the triage of COVID-19 patients and silently deployed a preliminary version of the deep neural network at New York University Langone Health during the first wave of the pandemic, which produced accurate predictions in real-time.
Journal ArticleDOI
Neuro-ophthalmic manifestations of coronavirus disease 19
TL;DR: Although COVID-19 primarily impacts the respiratory system, there are several reports of new onset neuro-ophthalmic conditions inCOVID-infected patients, and more research is needed to establish a causal relationship between CO VID-19 and neuro-ophilethalmic disease, and better understand pathogenesis.
References
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Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study.
Fei Zhou,Ting Yu,Ronghui Du,Guohui Fan,Ying Liu,Zhibo Liu,Jie Xiang,Yeming Wang,Bin Song,Xiaoying Gu,Xiaoying Gu,Lulu Guan,Yuan Wei,Li Hui,Xudong Wu,Jiuyang Xu,Shengjin Tu,Yi Zhang,Hua Chen,Bin Cao +19 more
TL;DR: Wang et al. as discussed by the authors used univariable and multivariable logistic regression methods to explore the risk factors associated with in-hospital death, including older age, high SOFA score and d-dimer greater than 1 μg/mL.
Journal ArticleDOI
Large artery ischaemic stroke in severe acute respiratory syndrome (SARS).
T. Umapathi,Ai Ching Kor,Narayanaswamy Venketasubramanian,C. C. Tchoyoson Lim,Boon Chuan Pang,Tseng Tsai Yeo,Cheng Chuan Lee,Poh Lian Lim,Poh Lian Lim,Kuperan Ponnudurai,Khoon Leong Chuah,Puay Hoon Tan,Dessmon Y.H. Tai,Sze Peng Brenda Ang +13 more
TL;DR: It is believed that increased vigilance against stroke and other thrombotic complications among critically-ill SARS patients in future outbreaks is needed, especially if treatment such as intravenous immunoglobulin, that increases pro-thrombosis tendency, is contemplated.
Journal ArticleDOI
Erythropoietin as candidate for supportive treatment of severe COVID-19.
Hannelore Ehrenreich,Karin Weissenborn,Martin Begemann,Martin Begemann,Markus Busch,Eduard Vieta,Kamilla W. Miskowiak +6 more
TL;DR: Evidence that supports the use of human recombinant erythropoietin (EPO) for ameliorating course and outcome of seriously ill COVID-19 patients is recap here and the research design for a double-blind placebo-controlled randomized clinical trial including severely affected patients is planned to start shortly.
Journal ArticleDOI
Revisiting the Protein C Pathway: An Opportunity for Adjunctive Intervention in COVID-19?
TL;DR: The objective of this study was to establish a baseline for the evaluation of the Recombinant Human Activated Protein C Worldwide Evaluation in Severe Sepsis.
Journal ArticleDOI
COVID-19-associated pulmonary and cerebral thromboembolic disease
TL;DR: A case of a 79-year-old woman that presented with stroke and was found to have COVID-19 pneumonia and concomitant large burden pulmonary arterial clot is reported.
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