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Open AccessJournal ArticleDOI

Large-Vessel Stroke as a Presenting Feature of Covid-19 in the Young.

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TLDR
Five patients younger than 50 years of age with large-vessel stroke and Covid-19 infection presented to a health system in New York City over a 2-week period with signs of stroke and infection.
Abstract
Stroke in Young Patients with Covid-19 Five patients younger than 50 years of age with large-vessel stroke and Covid-19 infection presented to a health system in New York City over a 2-week period....

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Citations
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Implications of COVID-19 in pediatric rheumatology.

TL;DR: In this review, a systematic literature search was conducted utilizing MEDLINE/PubMed and Scopus databases, and 231 COVID-19 patients with rheumatic diseases have been identified, and only one of these patients was a child.
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Presentations and mechanisms of CNS disorders related to COVID-19.

TL;DR: It is postulate that there are several different mechanisms involved in COVID-19–associated CNS dysfunction, particularly activation of inflammatory and thrombotic pathways and, in a few patients, a direct viral effect on the endothelium and the parenchyma.
Journal ArticleDOI

Cytokine storm induced by SARS-CoV-2 infection: The spectrum of its neurological manifestations.

TL;DR: Clinification of the pathogenic mechanisms of SARS-CoV-2 is needed to encourage prompt diagnosis and optimized care, and identifying the presence of cytokine storm in patients with neurological COVID-19 manifestations will facilitate avenues for treatment.
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Endothelial Dysfunction in the Brain: Setting the Stage for Stroke and Other Cerebrovascular Complications of COVID-19.

TL;DR: In this article, the authors explored the unique characteristics of the cerebral endothelium may be the underlying reason for the increased rates of cerebrovascular pathology associated with the coronavirus disease 2019 pandemic.
Journal ArticleDOI

The Impact of COVID-19 On Comorbidities: A Review Of Recent Updates For Combating It

TL;DR: In this article , the authors provided the latest information on the impact of the COVID-19 on pre-existing comorbidities such as CVDs, NDs, COPD, and other complications.
References
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Journal ArticleDOI

Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study.

TL;DR: Wang et al. as discussed by the authors used univariable and multivariable logistic regression methods to explore the risk factors associated with in-hospital death, including older age, high SOFA score and d-dimer greater than 1 μg/mL.
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Large artery ischaemic stroke in severe acute respiratory syndrome (SARS).

TL;DR: It is believed that increased vigilance against stroke and other thrombotic complications among critically-ill SARS patients in future outbreaks is needed, especially if treatment such as intravenous immunoglobulin, that increases pro-thrombosis tendency, is contemplated.
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Erythropoietin as candidate for supportive treatment of severe COVID-19.

TL;DR: Evidence that supports the use of human recombinant erythropoietin (EPO) for ameliorating course and outcome of seriously ill COVID-19 patients is recap here and the research design for a double-blind placebo-controlled randomized clinical trial including severely affected patients is planned to start shortly.
Journal ArticleDOI

Revisiting the Protein C Pathway: An Opportunity for Adjunctive Intervention in COVID-19?

TL;DR: The objective of this study was to establish a baseline for the evaluation of the Recombinant Human Activated Protein C Worldwide Evaluation in Severe Sepsis.
Journal ArticleDOI

COVID-19-associated pulmonary and cerebral thromboembolic disease

TL;DR: A case of a 79-year-old woman that presented with stroke and was found to have COVID-19 pneumonia and concomitant large burden pulmonary arterial clot is reported.
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