Large-Vessel Stroke as a Presenting Feature of Covid-19 in the Young.
Thomas J Oxley,J Mocco,Shahram Majidi,Christopher P. Kellner,Hazem Shoirah,I. Paul Singh,Reade De Leacy,Tomoyoshi Shigematsu,Travis R. Ladner,Kurt A. Yaeger,Maryna Skliut,Jesse Weinberger,Neha S. Dangayach,Joshua B. Bederson,Stanley Tuhrim,Johanna T Fifi +15 more
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TLDR
Five patients younger than 50 years of age with large-vessel stroke and Covid-19 infection presented to a health system in New York City over a 2-week period with signs of stroke and infection.Abstract:
Stroke in Young Patients with Covid-19 Five patients younger than 50 years of age with large-vessel stroke and Covid-19 infection presented to a health system in New York City over a 2-week period....read more
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Multinational Prevalence of Neurological Phenotypes in Patients Hospitalized with COVID-19
Trang T. Le,Alba Gutiérrez-Sacristán,Jiyeon Son,Chuan Hong,Andrew M South,Brett K Beaulieu-Jones,Ne Hooi Will Loh,Yuan Luo,Michele I. Morris,Kee Yuan Ngiam,Lav P Patel,Malarkodi J Samayamuthu,Emily Schriver,Amelia Lm Tan,Jason H. Moore,Tianxi Cai,Gilbert S. Omenn,Paul Avillach,Isaac S. Kohane,Shyam Visweswaran,Danielle L. Mowery,Zongqi Xia +21 more
TL;DR: In this paper, the prevalence of a wide range of neurological conditions among patients hospitalized with SARS-CoV-19 in geographically diverse multinational populations was defined, using electronic health record (EHR) data from 348 participating hospitals across 6 countries and 3 continents.
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Inflammation and the Link to Vascular Brain Health: Timing Is Brain
Katherine T. Mun,Jason D Hinman +1 more
TL;DR: Recognition of the phasic nature of inflammatory cascades on varying states of cerebrovascular disease is likely essential to the development and implementation of an anti-inflammatory strategy in the prevention, treatment, and repair of vascular brain injury.
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Long-term outcomes after NeuroCOVID: A 6-month follow-up study on 60 patients
TL;DR: In this paper , the authors evaluated the functional outcome and identified the risk factors of neurologic sequelae after COVID-19 associated with neurological manifestations (NeuroCOVID), and found that a significant residual disability was found in 51.7% of patients and impaired cognition in 68.9% of cases.
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Characteristics and outcomes of 100 consecutive patients with acute stroke and COVID-19.
Rajesh Benny,Rakeshsingh K Singh,Anil Venkitachalam,Rakesh Shyam Lalla,Rahul A Pandit,Keyur C Panchal,Vibhor Pardasani,Gunjan Chanchalani,Mheboob Basle,Vyankatesh Bolegave,Hunnur Manoj,Ashutosh N Shetty,Amit M Shah,Pawan Pai,Nilesh M Banthia,Shekhar Patil,Vishal Chafale,Bhavin Pujara,Sanjay Shah,Naresh Mehta,Vicky V Thakkar,Vikas Patel,Kishore V Shetty +22 more
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Brachial plexopathy as a complication of COVID-19.
Catherine Han,Andrew M Tarr,Alexandra N Gewirtz,Ulrike W. Kaunzner,Paula Roy-Burman,Todd S. Cutler,Daniel Jl MacGowan +6 more
TL;DR: In this article, a 52-year-old man with hypertension and newly diagnosed diabetes mellitus presented with hypoxic respiratory failure due to COVID-19 and developed severe brachial plexopathy.
References
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Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study.
Fei Zhou,Ting Yu,Ronghui Du,Guohui Fan,Ying Liu,Zhibo Liu,Jie Xiang,Yeming Wang,Bin Song,Xiaoying Gu,Xiaoying Gu,Lulu Guan,Yuan Wei,Li Hui,Xudong Wu,Jiuyang Xu,Shengjin Tu,Yi Zhang,Hua Chen,Bin Cao +19 more
TL;DR: Wang et al. as discussed by the authors used univariable and multivariable logistic regression methods to explore the risk factors associated with in-hospital death, including older age, high SOFA score and d-dimer greater than 1 μg/mL.
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Large artery ischaemic stroke in severe acute respiratory syndrome (SARS).
T. Umapathi,Ai Ching Kor,Narayanaswamy Venketasubramanian,C. C. Tchoyoson Lim,Boon Chuan Pang,Tseng Tsai Yeo,Cheng Chuan Lee,Poh Lian Lim,Poh Lian Lim,Kuperan Ponnudurai,Khoon Leong Chuah,Puay Hoon Tan,Dessmon Y.H. Tai,Sze Peng Brenda Ang +13 more
TL;DR: It is believed that increased vigilance against stroke and other thrombotic complications among critically-ill SARS patients in future outbreaks is needed, especially if treatment such as intravenous immunoglobulin, that increases pro-thrombosis tendency, is contemplated.
Journal ArticleDOI
Erythropoietin as candidate for supportive treatment of severe COVID-19.
Hannelore Ehrenreich,Karin Weissenborn,Martin Begemann,Martin Begemann,Markus Busch,Eduard Vieta,Kamilla W. Miskowiak +6 more
TL;DR: Evidence that supports the use of human recombinant erythropoietin (EPO) for ameliorating course and outcome of seriously ill COVID-19 patients is recap here and the research design for a double-blind placebo-controlled randomized clinical trial including severely affected patients is planned to start shortly.
Journal ArticleDOI
Revisiting the Protein C Pathway: An Opportunity for Adjunctive Intervention in COVID-19?
TL;DR: The objective of this study was to establish a baseline for the evaluation of the Recombinant Human Activated Protein C Worldwide Evaluation in Severe Sepsis.
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COVID-19-associated pulmonary and cerebral thromboembolic disease
TL;DR: A case of a 79-year-old woman that presented with stroke and was found to have COVID-19 pneumonia and concomitant large burden pulmonary arterial clot is reported.
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