Large-Vessel Stroke as a Presenting Feature of Covid-19 in the Young.
Thomas J Oxley,J Mocco,Shahram Majidi,Christopher P. Kellner,Hazem Shoirah,I. Paul Singh,Reade De Leacy,Tomoyoshi Shigematsu,Travis R. Ladner,Kurt A. Yaeger,Maryna Skliut,Jesse Weinberger,Neha S. Dangayach,Joshua B. Bederson,Stanley Tuhrim,Johanna T Fifi +15 more
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TLDR
Five patients younger than 50 years of age with large-vessel stroke and Covid-19 infection presented to a health system in New York City over a 2-week period with signs of stroke and infection.Abstract:
Stroke in Young Patients with Covid-19 Five patients younger than 50 years of age with large-vessel stroke and Covid-19 infection presented to a health system in New York City over a 2-week period....read more
Citations
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Pathogenetic profiling of COVID-19 and SARS-like viruses.
Zulkar Nain,Humayan Kabir Rana,Pietro Liò,Sheikh Mohammed Shariful Islam,Matthew A. Summers,Mohammad Ali Moni +5 more
TL;DR: Protein–chemical interactions suggest cyclosporine, resveratrol and quercetin as promising drug candidates against COVID-19 as well as other SARS-like viral infections.
Journal ArticleDOI
Cerebral Venous Thrombosis in COVID-19: A New York Metropolitan Cohort Study.
Fawaz Al-Mufti,Krishna Amuluru,Ramandeep Sahni,K. Bekelis,R. Karimi,Jonathan V Ogulnick,Jared B. Cooper,Philip Overby,Rolla Nuoman,Ambooj Tiwari,K. Berekashvili,Neha S. Dangayach,John W. Liang,Gaurav Gupta,Priyank Khandelwal,Jose F. Dominguez,Tolga Sursal,Haris Kamal,Katarina Dakay,Blake E.S. Taylor,Edwin Gulko,Mohammad El-Ghanem,Stephan A. Mayer,Chirag D. Gandhi +23 more
TL;DR: In this paper, the authors evaluated the demographic and clinical characteristics of cerebral venous thrombosis among patients hospitalized for coronavirus disease 2019 (COVID-19) at 6 tertiary care centers in the New York City metropolitan area.
Journal ArticleDOI
Neuropathogenesis of SARS-CoV-2 infection.
Shumayila Khan,James Gomes +1 more
TL;DR: The possibility of neurological damage caused by the SARS-CoV-2 virus demands immediate attention and investigation of the mechanisms involved, so as to customize the treatment of patients presenting with neurological complications.
Journal ArticleDOI
COVID-19 Infections and Clinical Outcomes in Patients with Multiple Myeloma in New York City: A Cohort Study from Five Academic Centers.
Malin Hultcrantz,Joshua Richter,Cara A. Rosenbaum,Dhwani Patel,Eric L. Smith,Neha Korde,Sydney X. Lu,Sham Mailankody,Urvi A Shah,Alexander M. Lesokhin,Hani Hassoun,Carlyn Tan,Francesco Maura,Andriy Derkach,Benjamin Diamond,Adriana C Rossi,Roger N. Pearse,Deepu Madduri,Ajai Chari,David Kaminetzky,Marc Braunstein,Christian Gordillo,Ran Reshef,Ying Taur,Ying Taur,Faith E. Davies,Sundar Jagannath,Ruben Niesvizky,Suzanne Lentzsch,Gareth J. Morgan,Ola Landgren +30 more
TL;DR: Medical records uncover clinical and demographic characteristics associated with severity of COVID-19 in a large multicenter cohort of patients with multiple myeloma.
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Neurological involvement in SARS-CoV-2 infection: A clinical systematic review
TL;DR: In this paper, the authors provide a clinical approach of SARS-CoV-2 neurological complications based on the direct or indirect (systemic/immune-mediated) role of the SARS CoV2 in their genesis, and a wide heterogeneity of these reports emerged concerning the extension of the clinical examination and ancillary exams performed.
References
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Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study.
Fei Zhou,Ting Yu,Ronghui Du,Guohui Fan,Ying Liu,Zhibo Liu,Jie Xiang,Yeming Wang,Bin Song,Xiaoying Gu,Xiaoying Gu,Lulu Guan,Yuan Wei,Li Hui,Xudong Wu,Jiuyang Xu,Shengjin Tu,Yi Zhang,Hua Chen,Bin Cao +19 more
TL;DR: Wang et al. as discussed by the authors used univariable and multivariable logistic regression methods to explore the risk factors associated with in-hospital death, including older age, high SOFA score and d-dimer greater than 1 μg/mL.
Journal ArticleDOI
Large artery ischaemic stroke in severe acute respiratory syndrome (SARS).
T. Umapathi,Ai Ching Kor,Narayanaswamy Venketasubramanian,C. C. Tchoyoson Lim,Boon Chuan Pang,Tseng Tsai Yeo,Cheng Chuan Lee,Poh Lian Lim,Poh Lian Lim,Kuperan Ponnudurai,Khoon Leong Chuah,Puay Hoon Tan,Dessmon Y.H. Tai,Sze Peng Brenda Ang +13 more
TL;DR: It is believed that increased vigilance against stroke and other thrombotic complications among critically-ill SARS patients in future outbreaks is needed, especially if treatment such as intravenous immunoglobulin, that increases pro-thrombosis tendency, is contemplated.
Journal ArticleDOI
Erythropoietin as candidate for supportive treatment of severe COVID-19.
Hannelore Ehrenreich,Karin Weissenborn,Martin Begemann,Martin Begemann,Markus Busch,Eduard Vieta,Kamilla W. Miskowiak +6 more
TL;DR: Evidence that supports the use of human recombinant erythropoietin (EPO) for ameliorating course and outcome of seriously ill COVID-19 patients is recap here and the research design for a double-blind placebo-controlled randomized clinical trial including severely affected patients is planned to start shortly.
Journal ArticleDOI
Revisiting the Protein C Pathway: An Opportunity for Adjunctive Intervention in COVID-19?
TL;DR: The objective of this study was to establish a baseline for the evaluation of the Recombinant Human Activated Protein C Worldwide Evaluation in Severe Sepsis.
Journal ArticleDOI
COVID-19-associated pulmonary and cerebral thromboembolic disease
TL;DR: A case of a 79-year-old woman that presented with stroke and was found to have COVID-19 pneumonia and concomitant large burden pulmonary arterial clot is reported.
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