Large-Vessel Stroke as a Presenting Feature of Covid-19 in the Young.
Thomas J Oxley,J Mocco,Shahram Majidi,Christopher P. Kellner,Hazem Shoirah,I. Paul Singh,Reade De Leacy,Tomoyoshi Shigematsu,Travis R. Ladner,Kurt A. Yaeger,Maryna Skliut,Jesse Weinberger,Neha S. Dangayach,Joshua B. Bederson,Stanley Tuhrim,Johanna T Fifi +15 more
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TLDR
Five patients younger than 50 years of age with large-vessel stroke and Covid-19 infection presented to a health system in New York City over a 2-week period with signs of stroke and infection.Abstract:
Stroke in Young Patients with Covid-19 Five patients younger than 50 years of age with large-vessel stroke and Covid-19 infection presented to a health system in New York City over a 2-week period....read more
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2021 ACC/AHA Key Data Elements and Definitions for Heart Failure: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Data Standards (Writing Committee to Develop Clinical Data Standards for Heart Failure)
Biykem Bozkurt,Ray E. Hershberger,Javed Butler,Kathleen L. Grady,Paul A. Heidenreich,Maria Lizza Isler,James K. Kirklin,William S. Weintraub +7 more
TL;DR: This article has been temporarily removed as it was inadvertently posted ahead of an agreed-upon embargo, but will be reinstated upon embargo expiry.
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The mental health of neurological doctors and nurses in Hunan Province, China during the initial stages of the COVID-19 outbreak.
TL;DR: The shortage of protective equipment led tobable anxiety, and young age led to probable depression in healthcare workers in neurology departments, which merits attention during the battle against COVID-19.
Journal ArticleDOI
Neurological Sequelae in Patients with COVID-19: A Histopathological Perspective.
Francesco Fisicaro,Mario Di Napoli,Aldo Liberto,Martina Fanella,Flavio Di Stasio,Manuela Pennisi,Rita Bella,Giuseppe Lanza,Gelsomina Mansueto +8 more
TL;DR: In this article, the authors provided a preliminary description of the relationship between SARS-CoV-2 and brain sequelae, despite the limited evidence available and the heterogeneity of the studies.
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Acute Stroke Presentation, Care, and Outcomes in Community Hospitals in Northern California During the COVID-19 Pandemic.
Mai N. Nguyen-Huynh,Xian Nan Tang,David R. Vinson,Alexander C. Flint,Janet G. Alexander,Melissa M Meighan,Molly Burnett,Stephen Sidney,Jeffrey Klingman +8 more
TL;DR: In this paper, SIP orders implemented to mitigate severe acute respiratory syndrome coronavirus 2 spread may inadvertently discourage patient care-seeking behavior for chronic lung cancer patients in the US.
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Diverse Immunological Factors Influencing Pathogenesis in Patients with COVID-19: A Review on Viral Dissemination, Immunotherapeutic Options to Counter Cytokine Storm and Inflammatory Responses
Ali A. Rabaan,Shamsah H. Al-Ahmed,Mohammed A. Garout,Ayman M. Al-Qaaneh,Anupam A Sule,Raghavendra Tirupathi,Abbas Al Mutair,Saad Alhumaid,Abdulkarim Hasan,Manish Dhawan,Ruchi Tiwari,Khan Sharun,Ranjan K. Mohapatra,Saikat Mitra,Talha Bin Emran,Muhammad Bilal,Rajendra Singh,Salem A. Alyami,Mohammad Ali Moni,Kuldeep Dhama +19 more
TL;DR: In this article, a review explains the interrelationships of hyper-inflammatory response or cytokine storm with organ damage and the disease severity and the authors have thrown light on the diverse mechanisms and risk factors that influence pathogenesis and the molecular pathways that lead to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and multiple organ damage.
References
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Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study.
Fei Zhou,Ting Yu,Ronghui Du,Guohui Fan,Ying Liu,Zhibo Liu,Jie Xiang,Yeming Wang,Bin Song,Xiaoying Gu,Xiaoying Gu,Lulu Guan,Yuan Wei,Li Hui,Xudong Wu,Jiuyang Xu,Shengjin Tu,Yi Zhang,Hua Chen,Bin Cao +19 more
TL;DR: Wang et al. as discussed by the authors used univariable and multivariable logistic regression methods to explore the risk factors associated with in-hospital death, including older age, high SOFA score and d-dimer greater than 1 μg/mL.
Journal ArticleDOI
Large artery ischaemic stroke in severe acute respiratory syndrome (SARS).
T. Umapathi,Ai Ching Kor,Narayanaswamy Venketasubramanian,C. C. Tchoyoson Lim,Boon Chuan Pang,Tseng Tsai Yeo,Cheng Chuan Lee,Poh Lian Lim,Poh Lian Lim,Kuperan Ponnudurai,Khoon Leong Chuah,Puay Hoon Tan,Dessmon Y.H. Tai,Sze Peng Brenda Ang +13 more
TL;DR: It is believed that increased vigilance against stroke and other thrombotic complications among critically-ill SARS patients in future outbreaks is needed, especially if treatment such as intravenous immunoglobulin, that increases pro-thrombosis tendency, is contemplated.
Journal ArticleDOI
Erythropoietin as candidate for supportive treatment of severe COVID-19.
Hannelore Ehrenreich,Karin Weissenborn,Martin Begemann,Martin Begemann,Markus Busch,Eduard Vieta,Kamilla W. Miskowiak +6 more
TL;DR: Evidence that supports the use of human recombinant erythropoietin (EPO) for ameliorating course and outcome of seriously ill COVID-19 patients is recap here and the research design for a double-blind placebo-controlled randomized clinical trial including severely affected patients is planned to start shortly.
Journal ArticleDOI
Revisiting the Protein C Pathway: An Opportunity for Adjunctive Intervention in COVID-19?
TL;DR: The objective of this study was to establish a baseline for the evaluation of the Recombinant Human Activated Protein C Worldwide Evaluation in Severe Sepsis.
Journal ArticleDOI
COVID-19-associated pulmonary and cerebral thromboembolic disease
TL;DR: A case of a 79-year-old woman that presented with stroke and was found to have COVID-19 pneumonia and concomitant large burden pulmonary arterial clot is reported.
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