Journal ArticleDOI
Rapid chromatographic technique for preparative separations with moderate resolution
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Abstract:
(11) Potassium ferricyanide has previously been used to convert w'c-1,2-dicarboxylate groups to double bonds. See, for example, L. F. Fieser and M. J. Haddadln, J. Am. Chem. Soc., 86, 2392 (1964). The oxidative dldecarboxylation of 1,2-dlcarboxyllc acids is, of course, a well-known process. See Inter alia (a) C. A. Grob, M. Ohta, and A. Weiss, Helv. Chim. Acta, 41, 1911 (1958); and (b) E. N. Cain, R. Vukov, and S. Masamune, J. Chem. Soc. D, 98 (1969).read more
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Synthesis of 1s,2r,3s,4r,5r-methyl[2,3,4-trihydroxy-5-(hydroxymbthyl)cyclopentyl]amine: a potent α-mannosidase inhibitor
TL;DR: The title carbocyclic amine 15, prepared in high yield from isoxazolidine 8 using efficient oxidation-epimerization-reduction sequence, is an inhibitor of mung bean αmannosidase II and a potent inhibitor of jack bean α-mannosidease as mentioned in this paper.
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A New Generation of "Cholaphanes": Steroid-Derived Macrocyclic Hosts with Enhanced Solubility and Controlled Flexibility.
Khadga M. Bhattarai,Anthony P. Davis,Justin J. Perry,Christopher J. Walter,Stephan Menzer,David J. Williams +5 more
TL;DR: The macrocyclic "cholaphanes" 3a-c were synthesized from the inexpensive steroid cholic acid and feature substantial cavities with inward-directed hydroxyl groups, suitable for binding polar molecules such as carbohydrates in nonpolar media.
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The effect of substituents on phthalocyanine photocytotoxicity
I. Rosenthal,E. Ben-Hur,Shafrira Greenberg,A. Concepcion-Lam,David M. Drew,Clifford C. Leznoff +5 more
TL;DR: The first synthesis of a metal‐free tetrahydroxy Pc is described and the photobiological activity for ZnPc was found to be the highest for the unsubstituted compound.
Journal ArticleDOI
Palladium catalysed aryl amination reactions in supercritical carbon dioxide.
TL;DR: Extension of the methodology to the N-arylation of N-silyldiarylamines, N-dicyclohexylphosphino-2',4',6'-triisopropyl-1,1'-biphenyl (X-Phos)(2 mol%) enabled the catalytic amination of aryl bromides and chlorides with N- silylanilines to be realised in excellent yield.
Journal ArticleDOI
Isolation and concentration techniques for capillary column gas chromatographic analysis
Colin F. Poole,S. A. Schuette +1 more
TL;DR: In this paper, a survey of different methods of preparation des echantillons for l'analyse chromatographique gazeuse sur colonne capillaire is presented.