Journal ArticleDOI
Rapid chromatographic technique for preparative separations with moderate resolution
Abstract:
(11) Potassium ferricyanide has previously been used to convert w'c-1,2-dicarboxylate groups to double bonds. See, for example, L. F. Fieser and M. J. Haddadln, J. Am. Chem. Soc., 86, 2392 (1964). The oxidative dldecarboxylation of 1,2-dlcarboxyllc acids is, of course, a well-known process. See Inter alia (a) C. A. Grob, M. Ohta, and A. Weiss, Helv. Chim. Acta, 41, 1911 (1958); and (b) E. N. Cain, R. Vukov, and S. Masamune, J. Chem. Soc. D, 98 (1969).read more
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A radical approach to the copper oxidative addition problem: Trifluoromethylation of bromoarenes.
TL;DR: It is demonstrated that this copper oxidative addition problem can be overcome with an aryl radical–capture mechanism, wherein the ariesl radical is generated through a silyl radical halogen abstraction in dual copper-photoredox catalysis.
Journal ArticleDOI
Metal Films Prepared by Stepwise Assembly. 2. Construction and Characterization of Colloidal Au and Ag Multilayers
Michael D. Musick,Christine D. Keating,L. Andrew Lyon,Steven L. Botsko,David J. Peña,William D. Holliway,Todd M. Mcevoy,John N. Richardson,Michael J. Natan +8 more
TL;DR: In this paper, the authors describe the stepwise, ligand-directed assembly, characterization, and prospective applications of three-dimensional Au and Ag nanoparticle, multilayered films.
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Effect of nitrogen fertilization upon the secondary chemistry and nutritional value of quaking aspen (Populus tremuloides Michx.) leaves for the large aspen tortrix (Choristoneura conflictana (Walker))
TL;DR: The results indicate that future studies of woody plant/insect defoliator interactions must consider plant carbon/nutrient balance as a potentially important control over the nutritional value of foliage for insect herbivores.
Journal ArticleDOI
C−H Bond Activation by a Ferric Methoxide Complex: Modeling the Rate-Determining Step in the Mechanism of Lipoxygenase
TL;DR: Comparison of [Fe(III)(PY5)(OMe)](OTf)(2) to other coordination complexes capable of hydrogen atom abstraction shows that, although a strong correlation exists between the thermodynamic driving force of reaction and the rate of reaction, other factors appear to further modulate the reactivity.
Journal ArticleDOI
High-throughput method for the production and analysis of large natural product libraries for drug discovery.
Gary R. Eldridge,Helene C. Vervoort,Chris M. Lee,Peadar A. Cremin,Caroline T. Williams,Shane M. Hart,Matt G. Goering,and Mark O'Neil-Johnson,Lu Zeng +8 more
TL;DR: Biological screening in the National Cancer Institute's in vitro panel of three cancer cell lines demonstrates that the process enables the discovery of active anticancer compounds not detected in the flash fractions from which the library originates.