Journal ArticleDOI
Rapid chromatographic technique for preparative separations with moderate resolution
Reads0
Chats0
Abstract:
(11) Potassium ferricyanide has previously been used to convert w'c-1,2-dicarboxylate groups to double bonds. See, for example, L. F. Fieser and M. J. Haddadln, J. Am. Chem. Soc., 86, 2392 (1964). The oxidative dldecarboxylation of 1,2-dlcarboxyllc acids is, of course, a well-known process. See Inter alia (a) C. A. Grob, M. Ohta, and A. Weiss, Helv. Chim. Acta, 41, 1911 (1958); and (b) E. N. Cain, R. Vukov, and S. Masamune, J. Chem. Soc. D, 98 (1969).read more
Citations
More filters
Journal ArticleDOI
Mechanism of formation of the Maillard protein cross-link pentosidine. Glucose, fructose, and ascorbate as pentosidine precursors.
TL;DR: The discovery that pentosidine can form not only from pentoses but also from hexoses and ascorbate raises major new questions concerning biochemical pathways of the Maillard reaction in vivo.
Journal ArticleDOI
Agrobacterium conjugation and gene regulation by N -acyl-L-homoserine lactones
TL;DR: The use of spectrometry shows that the conjugation factor of Agrobacterium tumefaciens is identical to synthetic N-(β-oxo-octan-l-oyl)-L-homoserine lactone and confirms that the synthetic compound is biologically active, the first example of a second messenger molecule in a bacterial conjugal system.
Journal ArticleDOI
Application of Ring-Closing Metathesis to the Synthesis of Rigidified Amino Acids and Peptides
TL;DR: Ruthenium complexes 1a and 1b have been applied to the ring-closing metathesis (RCM) reactions of a number of dienic substrates as mentioned in this paper.
Journal ArticleDOI
Biologically active metal-independent superoxide dismutase mimics.
James B. Mitchell,J Amram Samuni,Murali C. Krishna,William DeGraff,Min S. Ahn,Uri Samuni,Angelo Russo +6 more
TL;DR: A set of stable nitroxides that possess SOD-like activity, have the advantage of being low molecular weight, membrane permeable, and metal independent, and at pH 7.0 have reaction rate constants with O2.- protecting mammalian cells from damage induced by hypoxanthine/xanthine oxidase and H2O2.
Journal ArticleDOI
Native functionality in triple catalytic cross-coupling: sp3 C–H bonds as latent nucleophiles
Megan H. Shaw,Valerie W. Shurtleff,Jack A. Terrett,James D. Cuthbertson,David W. C. MacMillan +4 more
TL;DR: This mild approach takes advantage of a tunable HAT catalyst that exhibits predictable reactivity patterns based on enthalpic and bond polarity considerations to selectively functionalize α-amino and α-oxy sp3 C–H bonds in both cyclic and acyclic systems.