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Open AccessJournal ArticleDOI

The determination of ascorbic acid in whole blood and urine through the 2,4-dinitrophenylhydrazine derivative of dehydroascorbic acid

Joseph H. Roe, +1 more
- 01 Feb 1943 - 
- Vol. 147, Iss: 2, pp 399-407
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This article is published in Journal of Biological Chemistry.The article was published on 1943-02-01 and is currently open access. It has received 1689 citations till now. The article focuses on the topics: Ascorbic acid & Dehydroascorbic acid.

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Journal ArticleDOI

Studies on the tissue distribution of ascorbic acid.

TL;DR: The data presented in FIGURES 1 and 2 indicate that L-ascorbic a~id-1-C'~ is rapidly removed from the serum and transferred to such tissues as adrenal, kidney, and liver, and in the early time periods,such tissues as eye, muscle, testis, and brain accumulate only relatively small amounts of radioactive ascorbic acid.
Journal ArticleDOI

Mitigating effects of some antidotes on fluoride and arsenic induced free radical toxicity in mice ovary.

TL;DR: The induced toxicity was transient and reversible, and the withdrawal of the combined (NaF and As(2)O(3) for 30 days) treatment caused partial recovery in the ovary, which was more pronounced by treatment with vitamin C, calcium, or vitamin E alone and in combination.
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The effect of injected corticosterone on the release of adrenocorticotrophic hormone in rats exposed to acute stress.

TL;DR: The work of Yates, Leeman, Glenister & Dallman (1961) has re-emphasized the possible importance of the blood corticoids in exerting a negative feed-back control on pituitary adrenocorticotrophic activity and interpreted their results as implying that the mechanism of the release of ACTH involves a negativefeed-back by corticosterone in the blood.
Journal ArticleDOI

The synthesis of ascorbic acid in the rat deprived of vitamin A with and without addition of chloretone.

TL;DR: It is suggested that absence of vitamin A decreases the concentration of ascorbic acid in the tissues by interfering with its synthesis and not by causing excessive loss from the kidneys.
Journal ArticleDOI

Ascorbic acid from lime juice does not improve the iron status of iron-deficient women in rural Mexico

TL;DR: Increasing dietary AA by 25 mg at each of 2 meals/d did not improve iron status in iron-deficient women consuming diets high in phytate and nonheme iron.
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