Agriculture and Agri-Food Canada

About: Agriculture and Agri-Food Canada is a facility organization based out in Ottawa, Ontario, Canada. It is known for research contribution in the topics: Population & Soil water. The organization has 10921 authors who have published 21332 publications receiving 748193 citations. The organization is also known as: Department of Agriculture and Agri-Food.

Animal models to study acute and chronic intestinal inflammation in mammals

Abstract: Acute and chronic inflammatory diseases of the intestine impart a significant and negative impact on the health and well-being of human and non-human mammalian animals. Understanding the underlying mechanisms of inflammatory disease is mandatory to develop effective treatment and prevention strategies. As inflammatory disease etiologies are multifactorial, the use of appropriate animal models and associated metrics of disease are essential. In this regard, animal models used alone or in combination to study acute and chronic inflammatory disease of the mammalian intestine paired with commonly used inflammation-inducing agents are reviewed. This includes both chemical and biological incitants of inflammation, and both non-mammalian (i.e. nematodes, insects, and fish) and mammalian (i.e. rodents, rabbits, pigs, ruminants, dogs, and non-human primates) models of intestinal inflammation including germ-free, gnotobiotic, as well as surgical, and genetically modified animals. Importantly, chemical and biological incitants induce inflammation via a multitude of mechanisms, and intestinal inflammation and injury can vary greatly according to the incitant and animal model used, allowing studies to ascertain both long-term and short-term effects of inflammation. Thus, researchers and clinicians should be aware of the relative strengths and limitations of the various animal models used to study acute and chronic inflammatory diseases of the mammalian intestine, and the scope and relevance of outcomes achievable based on this knowledge. The ability to induce inflammation to mimic common human diseases is an important factor of a successful animal model, however other mechanisms of disease such as the amount of infective agent to induce disease, invasion mechanisms, and the effect various physiologic changes can have on inducing damage are also important features. In many cases, the use of multiple animal models in combination with both chemical and biological incitants is necessary to answer the specific question being addressed regarding intestinal disease. Some incitants can induce acute responses in certain animal models while others can be used to induce chronic responses; this review aims to illustrate the strengths and weaknesses in each animal model and to guide the choice of an appropriate acute or chronic incitant to facilitate intestinal disease.

Innovations in agronomy for food legumes. A review

Abstract: Although there is increasing awareness of the importance of food legumes in human, animal and soil health, adoption of improved production technologies for food legume crops is not proceeding at the same pace as for cereal crops. Over the previous decade, the only food legumes to have shown significant production increases have been chickpea, lentil and faba bean in North America, chickpea in Australia, and faba bean in Europe. In smallholder farming in developing countries, production trends have mostly been static or have declined over the past decade despite the existence of technology that should permit higher and more stable yields. Ability to reverse negative trends is jeopardized by climate change as food legumes are mostly grown rainfed and are being exposed to increasingly variable and extreme weather. This review examines recent innovations in cultivation technology for the major food legumes—chickpea, lentil, dry pea, faba bean, lupin, common bean, mung bean, black gram, cowpea, and pigeonpea—and explores constraints to their adoption, particularly by resource-poor smallholder farmers. Conservation agriculture, involving minimum soil disturbance, maximum soil cover, and diverse rotations, has contributed to sustainable cropping system production in large-scale commercial farming systems in the Americas, Europe, Australia, and Turkey. Temperate food legumes have been incorporated into such systems. Adoption of conservation agriculture is only just beginning for smallholder farming in Asia and Africa, catalyzed by the development of low-cost implements suitable for minimum tillage. Water use efficiency improves with conservation agriculture as it allows for earlier planting, reduced soil evaporation, better weed management, and increased access to nutrients. Ecosystem-based approaches to plant nutrition are evolving which place more reliance on accessing organic and mineral reservoirs than in replenishing the immediately available pool with chemical fertilizers, leading to enhanced nutrient use efficiency of cropping systems. Ecosystem-based approaches are also being applied to management of weeds, diseases, and insect pests of food legumes, again with decreased reliance on synthetic chemicals. In achieving sustainable agricultural production systems, there is increasing realization of the need to move towards the tenets of organic agriculture, as exemplified in conservation agriculture and ecosystem-based approaches to plant nutrition and pest management. This does not necessarily imply a desire to qualify for organic product certification but more a realization of the need for sustainable agriculture. The movement towards conservation and organic agriculture encourages greater inclusion of food legumes, and legumes generally, in cropping systems. Unfortunately, however, technology transfer to resource-poor farming situations, where most food legumes are produced, remains a major bottleneck to meeting global demand. More participatory approaches to technology development, testing, and dissemination are required than hitherto practiced. It is suggested that this process could be enhanced by better focusing on major constraints within the value addition chain for food legumes.

Current status and future strategy in breeding grasspea ( Lathyrus sativus )

Abstract: Efforts in grasspea (Lathyrus sativus) improvement have increased since the development of lines that are very low in the neurotoxin Beta-N-oxalyl-L-alpha-beta-diamino propionic acid (ODAP); also referred to as Beta-N oxalyl-amino-L-alanine (BOAA). Many programs now address several related aspects of improvement simultaneously. These include reduced ODAP concentrations, insect and disease resistance, nitrogen fixation, agronomic practices, fodder and forage production, and components for increased yielding ability. The coordinated, multidisciplinary approach now being applied to the genetic improvement of grasspea should allow the potential of this largely neglected grain legume to be fully realized.