Institution
Humboldt University of Berlin
Education•Berlin, Germany•
About: Humboldt University of Berlin is a education organization based out in Berlin, Germany. It is known for research contribution in the topics: Population & Medicine. The organization has 33671 authors who have published 61781 publications receiving 1908102 citations. The organization is also known as: Humboldt-Universität zu Berlin & Universitas Humboldtiana Berolinensis.
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Max Planck Society1, Yerevan Physics Institute2, Centre national de la recherche scientifique3, University of Hamburg4, Humboldt University of Berlin5, Durham University6, École Polytechnique7, Dublin Institute for Advanced Studies8, University of Montpellier9, Joseph Fourier University10, DSM11, North-West University12, Ruhr University Bochum13, Charles University in Prague14, University of Namibia15
TL;DR: In this paper, an alternative approach is proposed based on the detection and identification of EBL absorption features in high-energy spectra of objects of known redshift, which provides the most stringent upper limit to date on the EBL in the Opt-NIR band, which appears significantly lower than expected from the current direct estimates and very close to the absolute lower limit represented by the integrated light of resolved galaxies.
Abstract: The diffuse Extragalactic Background Light (EBL) contains unique information about the epochs of formation and the history of evolution of galaxies. Unfortunately, direct measurements are subject to large systematic uncertainties due to the difficulties in the accurate model-based subtraction of the bright foregrounds. An alternative approach is based on the detection and identification of EBL absorption features in high-energy spectra of objects of known redshift. Here we exploit this method on the blazars H 2356-309 (z=0.165) and 1ES 1101-232 (z=0.186), newly discovered at TeV energies by the H.E.S.S. Collaboration. They are the most distant sources with measured spectra known so far at these energies. Their hard spectra provide the most stringent upper limit to date on the EBL in the Opt--NIR band, which appears significantly lower than expected from the current "direct" estimates and very close to the absolute lower limit represented by the integrated light of resolved galaxies. In addition to important cosmological implications, this result shows that the intergalactic space is more transparent to gamma-rays than previously thought, expanding the horizon of the TeV Universe.
651 citations
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University of California, Santa Barbara1, Humboldt University of Berlin2, University of Southern California3, University of Chicago4, University of Erlangen-Nuremberg5, University of South Florida6, Yale University7, University of Cincinnati8, University of Georgia9, Syracuse University10, Smithsonian Institution11, Harvard University12, Natural History Museum13, Texas A&M University14, Pennsylvania State University15, University of Wisconsin-Madison16, Aix-Marseille University17, California State University, Fullerton18, University of California, Santa Cruz19, College of William & Mary20, University of Colorado Boulder21, Duke University22, Slovak Academy of Sciences23, University of North Carolina at Wilmington24
TL;DR: In this paper, a new data set of fossil occurrences representing 3.5 million specimens was presented, and it was shown that global and local diversity was less than twice as high in the Neogene as in the mid-Paleozoic.
Abstract: It has previously been thought that there was a steep Cretaceous and Cenozoic radiation of marine invertebrates. This pattern can be replicated with a new data set of fossil occurrences representing 3.5 million specimens, but only when older analytical protocols are used. Moreover, analyses that employ sampling standardization and more robust counting methods show a modest rise in diversity with no clear trend after the mid-Cretaceous. Globally, locally, and at both high and low latitudes, diversity was less than twice as high in the Neogene as in the mid-Paleozoic. The ratio of global to local richness has changed little, and a latitudinal diversity gradient was present in the early Paleozoic.
650 citations
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TL;DR: The literature on ameloblastoma of the jaw was reviewed, including publications from 1960 to 1993, and compared to the latest larger review, published by Small and Waldron in 1955, for clarification of therapeutic approaches.
Abstract: Available literature on ameloblastoma of the jaw was reviewed, including publications from 1960 to 1993, and compared to the latest larger review, published by Small and Waldron in 1955. The average age of patients with ameloblastoma is 36 years. In developing countries ameloblastomas occur in younger patients. Men and women are equally affected. Women are 4 years younger than men when ameloblastomas first occur, and the tumours appear to be larger in females. Dominant clinical symptoms such as painless swelling and slow growth are non-characteristic. The ratio of ameloblastoma of the mandible to maxilla is 5 to 1. Ameloblastomas of the mandible occur 12 years earlier than those of the maxilla. Ameloblastomas occur most frequently in the molar region of the mandible. In Blacks, ameloblastomas occur more frequently in the anterior region of the jaws. Radiologically, 50% of ameloblastomas appear as multilocular radiolucent lesions with sharp delineation. Histologically, one-third are plexiform, one-third follicular; other variants such as acanthomatous ameloblastoma occur in older patients. Two percent of ameloblastomas are peripheral tumours. Unicystic ameloblastomas occurring in younger patients have been found in 6%. Detailed data on 345 patients with ameloblastoma were evaluated for clarification of therapeutic approaches. Chemotherapy and radiation seem to be contraindicated. Ameloblastomas of the maxilla should be treated as radically as possible, ameloblastomas of the mandible should also be treated radically. However, ameloblastomas which radiologically appear as unilocular lesions may be treated conservatively (enucleation, curettage), whenever all areas of the cystic lumen are controllable intraoperatively. Unicystic ameloblastomas occurring in patients 15 years younger than those with multisystic ameloblastoma may be treated conservatively except in cases with invasion of epithelium into the cyst wall. Different recurrence rates have been found for histological variants of the ameloblastoma. Follicular ameloblastomas appear to recur more often than the plexiform type. Unicystic ameloblastomas reveal lower recurrence rates than “non-unicystic” ameloblastomas. The peripheral type of ameloblastoma may be excised, since conservative therapy results in low recurrence rates. Postoperative follow-up is most important in the therapy of ameloblastoma, because more than 50% of all recurrences occur within 5 years postoperatively.
647 citations
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Humboldt University of Berlin1, University of Leeds2, Ghent University3, Tilburg University4, Heidelberg University5, Max Planck Society6, University of California, Riverside7, University of Potsdam8, University of Virginia9, University of Milano-Bicocca10, University of Illinois at Chicago11, University of Koblenz and Landau12, Utrecht University13, University of Greifswald14
TL;DR: In this paper, the authors focus on research practices but also offer guidelines for reviewers, editors, journal management, teachers, granting institutions, and university promotion committees, highlighting some of the emerging and existing practical solutions that can facilitate implementation of these recommendations.
Abstract: Replicability of findings is at the heart of any empirical science. The aim of this article is to move the current replicability debate in psychology towards concrete recommendations for improvement. We focus on research practices but also offer guidelines for reviewers, editors, journal management, teachers, granting institutions, and university promotion committees, highlighting some of the emerging and existing practical solutions that can facilitate implementation of these recommendations. The challenges for improving replicability in psychological science are systemic. Improvement can occur only if changes are made at many levels of practice, evaluation, and reward. Copyright © 2013 John Wiley & Sons, Ltd.
645 citations
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TL;DR: The data suggest that innate immune recognition of LTA via LBP, CD14, and TLR-2 represents an important mechanism in the pathogenesis of systemic complications in the course of infectious diseases brought about by the clinically most important Gram-positive pathogens.
641 citations
Authors
Showing all 34115 results
Name | H-index | Papers | Citations |
---|---|---|---|
Karl J. Friston | 217 | 1267 | 217169 |
Peer Bork | 206 | 697 | 245427 |
Raymond J. Dolan | 196 | 919 | 138540 |
Stefan Schreiber | 178 | 1233 | 138528 |
Andreas Pfeiffer | 149 | 1756 | 131080 |
Thomas Hebbeker | 148 | 1984 | 114004 |
Thomas Lohse | 148 | 1237 | 101631 |
Jean Bousquet | 145 | 1288 | 96769 |
Hermann Kolanoski | 145 | 1279 | 96152 |
Josh Moss | 139 | 1019 | 89255 |
R. D. Kass | 138 | 1920 | 107907 |
W. Kozanecki | 138 | 1498 | 99758 |
U. Mallik | 137 | 1625 | 97439 |
C. Haber | 135 | 1507 | 98014 |
Christophe Royon | 134 | 1453 | 90249 |