Nanjing Tech University

About: Nanjing Tech University is a education organization based out in Nanjing, China. It is known for research contribution in the topics: Catalysis & Membrane. The organization has 21827 authors who have published 21794 publications receiving 364050 citations. The organization is also known as: Nangongda & Nánjīng Gōngyè Dàxúe.

A Phototheranostic Strategy to Continuously Deliver Singlet Oxygen in the Dark and Hypoxic Tumor Microenvironment

Abstract: Continuous irradiation during photodynamic therapy (PDT) inevitably induces tumor hypoxia, thereby weakening the PDT effect. In PDT-induced hypoxia, providing singlet oxygen from stored chemical energy may enhance the cell-killing effect and boost the therapeutic effect. Herein, we present a phototheranostic (DPPTPE@PEG-Py NPs) prepared by using a 2-pyridone-based diblock polymer (PEG-Py) to encapsulate a semiconducting, heavy-atom-free pyrrolopyrrolidone-tetraphenylethylene (DPPTPE) with high singlet-oxygen-generation ability both in dichloromethane and water. The PEG-Py can trap the 1 O2 generated from DPPTPE under laser irradiation and form a stable intermediate of endoperoxide, which can then release 1 O2 in the dark, hypoxic tumor microenvironment. Furthermore, fluorescence-imaging-guided phototherapy demonstrates that this phototheranostic could completely inhibit tumor growth with the help of laser irradiation.

Layer-controllable WS2-reduced graphene oxide hybrid nanosheets with high electrocatalytic activity for hydrogen evolution.

Abstract: In this study, an efficient poly(vinylpyrrolidone) (PVP)-assisted hydrothermal method for the in situ growth of WS2 nanosheets with layer-controllability on reduced graphene oxide (rGO) is reported. The number of layers (from a monolayer to ∼25 layers) of the exfoliated WS2 can be accurately controlled by adjusting the amount of PVP. The layer structure and the morphology of the as-prepared hybrids are confirmed by field emission scanning electron microscopy and high-resolution transmission microscopy. The X-ray diffraction, Raman, and X-ray photoemission spectroscopy of the obtained WS2–rGO hybrid nanosheets indicate highly crystallized structures, a clear Raman shift and a stoichiometry, which is dependent on the number of layers. Furthermore, these highly active and durable catalysts exhibit an electrocatalytic current density of 10 mA cm−2 at a small hydrogen evolution reaction (HER) overpotential (−170 mV) and a Tafel slope of 52 mV dec−1 with an excellent electrocatalytic stability (after 6 months storage).

High performance cobalt-free perovskite cathode for intermediate temperature solid oxide fuel cells

Abstract: Bi doping of SrFeO3−δ results in the formation of a structure with high symmetry and extraordinary electrochemical performance for Bi0.5Sr0.5FeO3-δ, which is capable of competing effectively with the current Co-based cathode benchmark with additional advantages of lower thermal expansion and cost.

Simultaneous morphology manipulation and upconversion luminescence enhancement of β-NaYF4:Yb3+/Er3+ microcrystals by simply tuning the KF dosage.

Abstract: A strategy has been adopted for simultaneous morphology manipulation and upconversion luminescence enhancement of β-NaYF4:Yb(3+)/Er(3+) microcrystals by simply tuning the KF dosage. X-ray power diffraction (XRD), field emission scanning electron microscopy (FE-SEM), transmission electron microscopy (TEM), X-ray photoelectron spectroscopy (XPS) and photoluminescence spectra (PL) were used to characterize the samples. The influence of molar ratio of KF to Y(3+) on the crystal phase and morphology has been systematically investigated and discussed. It is found that the molar ratio of KF to Y(3+) can strongly control the morphology of the as-synthesized β-NaYF4 samples because of the different capping effect of F(-) ions on the different crystal faces. The possible formation mechanism has been proposed on the basis of a series of time-dependent experiments. More importantly, the upconversion luminescence of β-NaYF4:Yb(3+)/Er(3+) was greatly enhanced by increasing the molar ratio of KF to RE(3+) (RE = Y, Yb, Er), which is attributed to the distortion of local crystal field symmetry around lanthanide ions through K(+) ions doping. This synthetic methodology is expected to provide a new strategy for simultaneous morphology control and remarkable upconversion luminescence enhancement of yttrium fluorides, which may be applicable for other rare earth fluorides.