Institution
Nanjing Tech University
Education•Nanjing, China•
About: Nanjing Tech University is a education organization based out in Nanjing, China. It is known for research contribution in the topics: Catalysis & Membrane. The organization has 21827 authors who have published 21794 publications receiving 364050 citations. The organization is also known as: Nangongda & Nánjīng Gōngyè Dàxúe.
Topics: Catalysis, Membrane, Adsorption, Chemistry, Microstructure
Papers published on a yearly basis
Papers
More filters
••
TL;DR: In this paper, the authors trace the source attribution of environmental burdens from municipal solid waste (MSW) at the macro level, identify the key factors in environment protection, and explore the involved mechanisms, life-cycle assessment (LCA) was used in the study.
Abstract: To trace the source attribution of environmental burdens from municipal solid waste (MSW) at the macro level, identify the key factors in environment protection, and explore the involved mechanisms, life-cycle assessment (LCA) was used in this study. The major environmental hazard emissions caused by MSW disposal in China during the last decade were carbon dioxide, methane, mercury, chromium, and arsenic emissions. Environmental benefits varied significantly with the use of alternatives to coal-based electricity generation technologies, indicating that the current MSW-incineration-based electricity generation in China is not absolutely cleaner than the advanced coal-based electricity generation technology. Effective measures to reduce the environmental impact include improving electricity generation efficiency, reducing direct mercury emissions, maximizing the recycling system, providing separate food waste disposal, and optimizing landfill leachate management.
106 citations
••
TL;DR: A simple and designable leather based e‐skin is reported by merging the natural sophisticated structure and wearing comfort of leather with the multifunctional properties of nanomaterials to mimic or even outshine the functions of real skin.
Abstract: Electronic skin (e-skin), an important part toward the realization of artificial intelligence, has been developing through comprehending, mimicking, and eventually outperforming skin in some aspects. Most of the e-skin substrates are flexible polymers, such as polydimethylsiloxane (PDMS). Although PDMS was found to be biocompatible, it is not suitable for long-time wearing due to its air impermeability. This study reports a simple and designable leather based e-skin by merging the natural sophisticated structure and wearing comfort of leather with the multifunctional properties of nanomaterials. The leather based e-skin could make leather, "the dead skin," repurposed for its sensing capabilities. This e-skin can be applied in flexible pressure sensors, displays, user-interactive devices, etc. It provides a new class of materials for the development of multifunctional e-skin to mimic or even outshine the functions of real skin.
106 citations
••
TL;DR: Improving the deep-tissue phototherapy efficiency in the near-infrared (NIR) region has become one of the major challenges in clinics for cancer treatment.
Abstract: Improving the deep-tissue phototherapy (PDT) efficiency in the near-infrared (NIR) region has become one of the major challenges in clinics for cancer treatment. Developing intelligent photosensitizers (PSs) responding to tumor-specific signals sensitively to minimize side effects is another major challenge for tumor phototherapy. Herein, three phenyl-based boron dipyrromethene (BODIPY) compounds with different numbers of diethylaminophenyl groups introduced onto the BODIPY core have been designed and synthesized by the Knoevenagel condensation reaction. The absorbance of these compounds (BDPmPh, BDPbiPh, and BDPtriPh) can be controlled easily for realizing the tunable penetration depth. Moreover, the diethylamino groups in these designed PSs can serve as proton acceptors triggered by the low pH in lysosomes which can enhance the efficacy of photodynamic and photothermal therapy. The corresponding nanoparticles (NPs) of the compounds are prepared through a nanoprecipitation method and in vitro studies demonstrate that the ultra-low drug dosage of BDPtriPh NPs (half-maximal inhibitory concentration, IC50 = 4.16 μM) is much lower than that of BDPmPh NPs (50.09 μM) and BDPbiPh NPs (22.4 μM). In vivo fluorescence imaging shows that these NPs can be passively targeted to tumors by the enhanced permeability and retention (EPR) effect, and BDPtriPh NPs exhibit the fastest accumulation (about 4 hours). In vivo phototherapy indicates that BDPtriPh NPs with the longest NIR absorbance (813 nm) and highest photothermal conversion efficiency (60.5%) can effectively inhibit tumor growth and reduce side effects to normal tissues. This study provides a strategy to modulate the photoconversion characteristics of PSs for both penetration-depth-tunable and pH-dependent PDT/PTT synergistic cancer therapy in clinics.
106 citations
••
TL;DR: A rational design of stabilized high-porosity meso-PCPs is proposed, employing a low-symmetry ligand in combination with the shortest linker, formic acid, enabling highly selective and effective separation of C2H2 from C2h2/CO2 mixtures at 298 K, as verified by binding energy (BE) and electrostatic potentials (ESP) calculations.
Abstract: The prevalence of the condensed phase, interpenetration, and fragility of mesoporous coordination polymers (meso-PCPs) featuring dense open metal sites (OMSs) place strict limitations on their preparation, as revealed by experimental and theoretical reticular chemistry investigations. Herein, we propose a rational design of stabilized high-porosity meso-PCPs, employing a low-symmetry ligand in combination with the shortest linker, formic acid. The resulting dimeric clusters (PCP-31 and PCP-32) exhibit high surface areas, ultrahigh porosities, and high OMS densities (3.76 and 3.29 mmol g–1, respectively), enabling highly selective and effective separation of C2H2 from C2H2/CO2 mixtures at 298 K, as verified by binding energy (BE) and electrostatic potentials (ESP) calculations.
106 citations
••
TL;DR: PBV NPs will not only be powerful in resolving the paradox between traditional type II PDT and hypoxia, but also successfully prevent tumor metastasis after type I PDT treatment, enabling enhancement of existing hypoxic-and-metastatic tumor treatment.
Abstract: Hypoxia severely impedes photodynamic therapy (PDT) efficiency. Worse still, considerable tumor metastasis will occur after PDT. Herein, an organic superoxide radical (O2 ∙- ) nano-photogenerator as a highly effcient type I photosensitizer with robust vascular-disrupting efficiency to combat these thorny issues is designed. Boron difluoride dipyrromethene (BODIPY)-vadimezan conjugate (BDPVDA) is synthesized and enwrapped in electron-rich polymer-brushes methoxy-poly(ethylene glycol)-b-poly(2-(diisopropylamino) ethyl methacrylate) (mPEG- PPDA) to afford nanosized hydrophilic type I photosensitizer (PBV NPs). Owing to outstanding core-shell intermolecular electron transfer between BDPVDA and mPEG-PPDA, remarkable O2 ∙- can be produced by PBV NPs under near-infrared irradiation even in severe hypoxic environment (2% O2 ), thus to accomplish effective hypoxic-tumor elimination. Simultaneously, the efficient ester-bond hydrolysis of BDPVDA in the acidic tumor microenvironment allows vadimezan release from PBV NPs to disrupt vasculature, facilitating the shut-down of metastatic pathways. As a result, PBV NPs will not only be powerful in resolving the paradox between traditional type II PDT and hypoxia, but also successfully prevent tumor metastasis after type I PDT treatment (no secondary-tumors found in 70 days and 100% survival rate), enabling enhancement of existing hypoxic-and-metastatic tumor treatment.
106 citations
Authors
Showing all 22047 results
Name | H-index | Papers | Citations |
---|---|---|---|
Yi Chen | 217 | 4342 | 293080 |
Richard H. Friend | 169 | 1182 | 140032 |
Hua Zhang | 163 | 1503 | 116769 |
Wei Huang | 139 | 2417 | 93522 |
Jian Zhou | 128 | 3007 | 91402 |
Haiyan Wang | 119 | 1674 | 86091 |
Jian Liu | 117 | 2090 | 73156 |
Lain-Jong Li | 113 | 627 | 58035 |
Hong Wang | 110 | 1633 | 51811 |
Jun-Jie Zhu | 103 | 754 | 41655 |
Stefan Kaskel | 101 | 705 | 36201 |
Hong Liu | 100 | 1905 | 57561 |
Dirk De Vos | 96 | 642 | 33214 |
Peng Li | 95 | 1548 | 45198 |
Feng Liu | 95 | 1067 | 38478 |