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Showing papers on "The Internet published in 2015"


Journal ArticleDOI
TL;DR: An overview of the Internet of Things with emphasis on enabling technologies, protocols, and application issues, and some of the key IoT challenges presented in the recent literature are provided and a summary of related research work is provided.
Abstract: This paper provides an overview of the Internet of Things (IoT) with emphasis on enabling technologies, protocols, and application issues. The IoT is enabled by the latest developments in RFID, smart sensors, communication technologies, and Internet protocols. The basic premise is to have smart sensors collaborate directly without human involvement to deliver a new class of applications. The current revolution in Internet, mobile, and machine-to-machine (M2M) technologies can be seen as the first phase of the IoT. In the coming years, the IoT is expected to bridge diverse technologies to enable new applications by connecting physical objects together in support of intelligent decision making. This paper starts by providing a horizontal overview of the IoT. Then, we give an overview of some technical details that pertain to the IoT enabling technologies, protocols, and applications. Compared to other survey papers in the field, our objective is to provide a more thorough summary of the most relevant protocols and application issues to enable researchers and application developers to get up to speed quickly on how the different protocols fit together to deliver desired functionalities without having to go through RFCs and the standards specifications. We also provide an overview of some of the key IoT challenges presented in the recent literature and provide a summary of related research work. Moreover, we explore the relation between the IoT and other emerging technologies including big data analytics and cloud and fog computing. We also present the need for better horizontal integration among IoT services. Finally, we present detailed service use-cases to illustrate how the different protocols presented in the paper fit together to deliver desired IoT services.

6,131 citations


Journal ArticleDOI
TL;DR: The definitions, architecture, fundamental technologies, and applications of IoT are systematically reviewed and the major challenges which need addressing by the research community and corresponding potential solutions are investigated.
Abstract: In recent year, the Internet of Things (IoT) has drawn significant research attention. IoT is considered as a part of the Internet of the future and will comprise billions of intelligent communicating `things'. The future of the Internet will consist of heterogeneously connected devices that will further extend the borders of the world with physical entities and virtual components. The Internet of Things (IoT) will empower the connected things with new capabilities. In this survey, the definitions, architecture, fundamental technologies, and applications of IoT are systematically reviewed. Firstly, various definitions of IoT are introduced; secondly, emerging techniques for the implementation of IoT are discussed; thirdly, some open issues related to the IoT applications are explored; finally, the major challenges which need addressing by the research community and corresponding potential solutions are investigated.

5,295 citations


Journal ArticleDOI
TL;DR: The fields of application for IoT technologies are as numerous as they are diverse, as IoT solutions are increasingly extending to virtually all areas of everyday.
Abstract: It has been next to impossible in the past months not to come across the term ‘‘Internet of Things’’ (IoT) one way or another. Especially the past year has seen a tremendous surge of interest in the Internet of Things. Consortia have been formed to define frameworks and standards for the IoT. Companies have started to introduce numerous IoTbased products and services. And a number of IoT-related acquisitions have been making the headlines, including, e.g., the prominent takeover of Nest by Google for $3.2 billion and the subsequent acquisitions of Dropcam by Nest and of SmartThings by Samsung. Politicians as well as practitioners increasingly acknowledge the Internet of Things as a real business opportunity, and estimates currently suggest that the IoT could grow into a market worth $7.1 trillion by 2020 (IDC 2014). While the term Internet of Things is now more and more broadly used, there is no common definition or understanding today of what the IoT actually encompasses. The origins of the term date back more than 15 years and have been attributed to the work of the Auto-ID Labs at the Massachusetts Institute of Technology (MIT) on networked radio-frequency identification (RFID) infrastructures (Atzori et al. 2010; Mattern and Floerkemeier 2010). Since then, visions for the Internet of Things have been further developed and extended beyond the scope of RFID technologies. The International Telecommunication Union (ITU) for instance now defines the Internet of Things as ‘‘a global infrastructure for the Information Society, enabling advanced services by interconnecting (physical and virtual) things based on, existing and evolving, interoperable information and communication technologies’’ (ITU 2012). At the same time, a multitude of alternative definitions has been proposed. Some of these definitions exhibit an emphasis on the things which become connected in the IoT. Other definitions focus on Internet-related aspects of the IoT, such as Internet protocols and network technology. And a third type centers on semantic challenges in the IoT relating to, e.g., the storage, search and organization of large volumes of information (Atzori et al. 2010). The fields of application for IoT technologies are as numerous as they are diverse, as IoT solutions are increasingly extending to virtually all areas of everyday. The most prominent areas of application include, e.g., the smart industry, where the development of intelligent production systems and connected production sites is often discussed under the heading of Industry 4.0. In the smart home or building area, intelligent thermostats and security systems are receiving a lot of attention, while smart energy applications focus on smart electricity, gas and water meters. Smart transport solutions include, e.g., vehicle fleet tracking and mobile ticketing, while in the smart health area, topics such as patients’ surveillance and chronic disease management are being addressed. And in the context of Accepted after one revision by Prof. Dr. Sinz.

3,499 citations


Journal ArticleDOI
TL;DR: Five IoT technologies that are essential in the deployment of successful IoT-based products and services are presented and three IoT categories for enterprise applications used to enhance customer value are discussed and the real option approach is illustrated.

2,024 citations


Journal ArticleDOI
TL;DR: A web server to predict the functional effect of single or multiple amino acid substitutions, insertions and deletions using the prediction tool PROVEAN, which provides rapid analysis of protein variants from any organisms, and also supports high-throughput analysis for human and mouse variants at both the genomic and protein levels.
Abstract: Summary: We present a web server to predict the functional effect of single or multiple amino acid substitutions, insertions and deletions using the prediction tool PROVEAN. The server provides rapid analysis of protein variants from any organisms, and also supports high-throughput analysis for human and mouse variants at both the genomic and protein levels. Availability and implementation: The web server is freely available and open to all users with no login requirements at http://provean.jcvi.org. Contact: gro.ivcj@nahca Supplementary information: Supplementary data are available at Bioinformatics online.

1,886 citations


Journal ArticleDOI
TL;DR: MDTraj is a modern, lightweight, and fast software package for analyzing MD simulations that simplifies the analysis of MD data and connects these datasets with the modern interactive data science software ecosystem in Python.

1,480 citations


Journal ArticleDOI
TL;DR: The current state of research on the Internet of Things is reported on by examining the literature, identifying current trends, describing challenges that threaten IoT diffusion, presenting open research questions and future directions and compiling a comprehensive reference list to assist researchers.
Abstract: The Internet of Things is a paradigm where everyday objects can be equipped with identifying, sensing, networking and processing capabilities that will allow them to communicate with one another and with other devices and services over the Internet to accomplish some objective. Ultimately, IoT devices will be ubiquitous, context-aware and will enable ambient intelligence. This article reports on the current state of research on the Internet of Things by examining the literature, identifying current trends, describing challenges that threaten IoT diffusion, presenting open research questions and future directions and compiling a comprehensive reference list to assist researchers.

1,301 citations


Journal ArticleDOI
TL;DR: This survey analyzes existing protocols and mechanisms to secure communications in the IoT, as well as open research issues and analyzes the open challenges and strategies for future research work in the area.
Abstract: The Internet of Things (IoT) introduces a vision of a future Internet where users, computing systems, and everyday objects possessing sensing and actuating capabilities cooperate with unprecedented convenience and economical benefits. As with the current Internet architecture, IP-based communication protocols will play a key role in enabling the ubiquitous connectivity of devices in the context of IoT applications. Such communication technologies are being developed in line with the constraints of the sensing platforms likely to be employed by IoT applications, forming a communications stack able to provide the required power—efficiency, reliability, and Internet connectivity. As security will be a fundamental enabling factor of most IoT applications, mechanisms must also be designed to protect communications enabled by such technologies. This survey analyzes existing protocols and mechanisms to secure communications in the IoT, as well as open research issues. We analyze how existing approaches ensure fundamental security requirements and protect communications on the IoT, together with the open challenges and strategies for future research work in the area. This is, as far as our knowledge goes, the first survey with such goals.

968 citations


BookDOI
TL;DR: The online course in Biological Wastewater Treatment from UNESCO-IHE as mentioned in this paper is an online course on modeling and design of wastewater treatment plants with a focus on wastewater treatment plant design and operation.
Abstract: For information on the online course in Biological Wastewater Treatment from UNESCO-IHE, visit: http://www.iwapublishing.co.uk/books/biological-wastewater-treatment-online-course-principles-modeling-and-design Over the past twenty years, the knowledge and understanding of wastewater treatment have advanced extensively and moved away from empirically-based approaches to a first principles approach embracing chemistry, microbiology, physical and bioprocess engineering, and mathematics. Many of these advances have matured to the degree that they have been codified into mathematical models for simulation with computers. For a new generation of young scientists and engineers entering the wastewater treatment profession, the quantity, complexity and diversity of these new developments can be overwhelming, particularly in developing countries where access is not readily available to advanced level tertiary education courses in wastewater treatment. Biological Wastewater Treatment addresses this deficiency. It assembles and integrates the postgraduate course material of a dozen or so professors from research groups around the world that have made significant contributions to the advances in wastewater treatment. The book forms part of an internet-based curriculum in biological wastewater treatment which also includes: * Summarized lecture handouts of the topics covered in book * Filmed lectures by the author professors * Tutorial exercises for students self-learning Upon completion of this curriculum the modern approach of modelling and simulation to wastewater treatment plant design and operation, be it activated sludge, biological nitrogen and phosphorus removal, secondary settling tanks or biofilm systems, can be embraced with deeper insight, advanced knowledge and greater confidence.

948 citations


Journal ArticleDOI
TL;DR: A generally accepted definition for SDN is presented, including decoupling the control plane from the data plane and providing programmability for network application development, and its three-layer architecture is dwelled on, including an infrastructure layer, a control layer, and an application layer.
Abstract: Emerging mega-trends (e.g., mobile, social, cloud, and big data) in information and communication technologies (ICT) are commanding new challenges to future Internet, for which ubiquitous accessibility, high bandwidth, and dynamic management are crucial. However, traditional approaches based on manual configuration of proprietary devices are cumbersome and error-prone, and they cannot fully utilize the capability of physical network infrastructure. Recently, software-defined networking (SDN) has been touted as one of the most promising solutions for future Internet. SDN is characterized by its two distinguished features, including decoupling the control plane from the data plane and providing programmability for network application development. As a result, SDN is positioned to provide more efficient configuration, better performance, and higher flexibility to accommodate innovative network designs. This paper surveys latest developments in this active research area of SDN. We first present a generally accepted definition for SDN with the aforementioned two characteristic features and potential benefits of SDN. We then dwell on its three-layer architecture, including an infrastructure layer, a control layer, and an application layer, and substantiate each layer with existing research efforts and its related research areas. We follow that with an overview of the de facto SDN implementation (i.e., OpenFlow). Finally, we conclude this survey paper with some suggested open research challenges.

894 citations


Journal ArticleDOI
TL;DR: The different characteristics and potentials of different prediction techniques in recommendation systems are explored in order to serve as a compass for research and practice in the field of recommendation systems.

Journal ArticleDOI
01 Jan 2015-Database
TL;DR: One of the most comprehensive collections of human gene-disease associations and a valuable set of tools for investigating the molecular mechanisms underlying diseases of genetic origin, designed to fulfill the needs of different user profiles, are offered.
Abstract: DisGeNET is a comprehensive discovery platform designed to address a variety of questions concerning the genetic underpinning of human diseases. DisGeNET contains over 380,000 associations between >16,000 genes and 13,000 diseases, which makes it one of the largest repositories currently available of its kind. DisGeNET integrates expert-curated databases with text-mined data, covers information on Mendelian and complex diseases, and includes data from animal disease models. It features a score based on the supporting evidence to prioritize gene-disease associations. It is an open access resource available through a web interface, a Cytoscape plugin and as a Semantic Web resource. The web interface supports user-friendly data exploration and navigation. DisGeNET data can also be analysed via the DisGeNET Cytoscape plugin, and enriched with the annotations of other plugins of this popular network analysis software suite. Finally, the information contained in DisGeNET can be expanded and complemented using Semantic Web technologies and linked to a variety of resources already present in the Linked Data cloud. Hence, DisGeNET offers one of the most comprehensive collections of human gene-disease associations and a valuable set of tools for investigating the molecular mechanisms underlying diseases of genetic origin, designed to fulfill the needs of different user profiles, including bioinformaticians, biologists and health-care practitioners. Database URL: http://www.disgenet.org/

Journal ArticleDOI
TL;DR: The repertoire of profile hidden Markov model libraries, which are used for annotation of query sequences with protein families and domains, has been expanded to include the libraries from CATH-Gene3D, PIRSF, Superfamily and TIGRFAMs.
Abstract: The HMMER website, available at http://www.ebi.ac.uk/Tools/hmmer/, provides access to the protein homology search algorithms found in the HMMER software suite. Since the first release of the website in 2011, the search repertoire has been expanded to include the iterative search algorithm, jackhmmer. The continued growth of the target sequence databases means that traditional tabular representations of significant sequence hits can be overwhelming to the user. Consequently, additional ways of presenting homology search results have been developed, allowing them to be summarised according to taxonomic distribution or domain architecture. The taxonomy and domain architecture representations can be used in combination to filter the results according to the needs of a user. Searches can also be restricted prior to submission using a new taxonomic filter, which not only ensures that the results are specific to the requested taxonomic group, but also improves search performance. The repertoire of profile hidden Markov model libraries, which are used for annotation of query sequences with protein families and domains, has been expanded to include the libraries from CATH-Gene3D, PIRSF, Superfamily and TIGRFAMs. Finally, we discuss the relocation of the HMMER webserver to the European Bioinformatics Institute and the potential impact that this will have.

Journal ArticleDOI
TL;DR: This work demonstrates how to recruit participants using Facebook, incentivize them effectively, and maximize their engagement, and outlines the most important opportunities and challenges associated with using Facebook for research.
Abstract: Facebook is rapidly gaining recognition as a powerful research tool for the social sciences. It constitutes a large and diverse pool of participants, who can be selectively recruited for both online and offline studies. Additionally, it facilitates data collection by storing detailed records of its users' demographic profiles, social interactions, and behaviors. With participants' consent, these data can be recorded retrospectively in a convenient, accurate, and inexpensive way. Based on our experience in designing, implementing, and maintaining multiple Facebook-based psychological studies that attracted over 10 million participants, we demonstrate how to recruit participants using Facebook, incentivize them effectively, and maximize their engagement. We also outline the most important opportunities and challenges associated with using Facebook for research, provide several practical guidelines on how to successfully implement studies on Facebook, and finally, discuss ethical considerations.

Journal ArticleDOI
TL;DR: A thorough overview and analysis of the main approaches to entity linking is presented, and various applications, the evaluation of entity linking systems, and future directions are discussed.
Abstract: The large number of potential applications from bridging web data with knowledge bases have led to an increase in the entity linking research. Entity linking is the task to link entity mentions in text with their corresponding entities in a knowledge base. Potential applications include information extraction, information retrieval, and knowledge base population. However, this task is challenging due to name variations and entity ambiguity. In this survey, we present a thorough overview and analysis of the main approaches to entity linking, and discuss various applications, the evaluation of entity linking systems, and future directions.

Journal ArticleDOI
TL;DR: The security issues that arise due to the very nature of cloud computing are detailed and the recent solutions presented in the literature to counter the security issues are presented.

Journal ArticleDOI
Damian Smedley1, Syed Haider2, Steffen Durinck3, Luca Pandini4, Paolo Provero5, Paolo Provero4, James E. Allen6, Olivier Arnaiz7, Mohammad Awedh8, Richard Baldock9, Giulia Barbiera4, Philippe Bardou10, Tim Beck11, Andrew Blake, Merideth Bonierbale12, Anthony J. Brookes11, Gabriele Bucci4, Iwan Buetti4, Sarah W. Burge6, Cédric Cabau10, Joseph W. Carlson13, Claude Chelala14, Charalambos Chrysostomou11, Davide Cittaro4, Olivier Collin15, Raul Cordova12, Rosalind J. Cutts14, Erik Dassi16, Alex Di Genova17, Anis Djari10, Anthony Esposito18, Heather Estrella18, Eduardo Eyras19, Eduardo Eyras20, Julio Fernandez-Banet18, Simon A. Forbes1, Robert C. Free11, Takatomo Fujisawa, Emanuela Gadaleta14, Jose Manuel Garcia-Manteiga4, David Goodstein13, Kristian Gray6, José Afonso Guerra-Assunção14, Bernard Haggarty9, Dong Jin Han21, Byung Woo Han21, Todd W. Harris22, Jayson Harshbarger, Robert K. Hastings11, Richard D. Hayes13, Claire Hoede10, Shen Hu23, Zhi-Liang Hu24, Lucie N. Hutchins, Zhengyan Kan18, Hideya Kawaji, Aminah Keliet10, Arnaud Kerhornou6, Sunghoon Kim21, Rhoda Kinsella6, Christophe Klopp10, Lei Kong25, Daniel Lawson6, Dejan Lazarevic4, Ji Hyun Lee21, Thomas Letellier10, Chuan-Yun Li25, Pietro Liò26, Chu Jun Liu25, Jie Luo6, Alejandro Maass17, Jérôme Mariette10, Thomas Maurel6, Stefania Merella4, Azza M. Mohamed8, François Moreews10, Ibounyamine Nabihoudine10, Nelson Ndegwa27, Céline Noirot10, Cristian Perez-Llamas20, Michael Primig28, Alessandro Quattrone16, Hadi Quesneville10, Davide Rambaldi4, James M. Reecy24, Michela Riba4, Steven Rosanoff6, Amna A. Saddiq8, Elisa Salas12, Olivier Sallou15, Rebecca Shepherd1, Reinhard Simon12, Linda Sperling7, William Spooner29, Daniel M. Staines6, Delphine Steinbach10, Kevin R. Stone, Elia Stupka4, Jon W. Teague1, Abu Z. Dayem Ullah14, Jun Wang25, Doreen Ware29, Marie Wong-Erasmus, Ken Youens-Clark29, Amonida Zadissa6, Shi Jian Zhang25, Arek Kasprzyk8, Arek Kasprzyk4 
TL;DR: The latest version of the BioMart Community Portal comes with many new databases that have been created by the ever-growing community and comes with better support and extensibility for data analysis and visualization tools.
Abstract: The BioMart Community Portal (www.biomart.org) is a community-driven effort to provide a unified interface to biomedical databases that are distributed worldwide. The portal provides access to numerous database projects supported by 30 scientific organizations. It includes over 800 different biological datasets spanning genomics, proteomics, model organisms, cancer data, ontology information and more. All resources available through the portal are independently administered and funded by their host organizations. The BioMart data federation technology provides a unified interface to all the available data. The latest version of the portal comes with many new databases that have been created by our ever-growing community. It also comes with better support and extensibility for data analysis and visualization tools. A new addition to our toolbox, the enrichment analysis tool is now accessible through graphical and web service interface. The BioMart community portal averages over one million requests per day. Building on this level of service and the wealth of information that has become available, the BioMart Community Portal has introduced a new, more scalable and cheaper alternative to the large data stores maintained by specialized organizations.

Journal ArticleDOI
TL;DR: This position paper briefly introduces the concept of big data, including its definition, features, and value, and identifies from different perspectives the significance and opportunities that big data brings to us.

Journal ArticleDOI
TL;DR: The EFI-EST (Enzyme Function Initiative-Enzyme Similarity Tool) web tool is announced that is available without cost for the automated generation of SSNs by the community and is designed as a tutorial that will allow members of the community to use the E FI-EST web tool for exploring sequence/function space in protein families.

Journal ArticleDOI
TL;DR: This article presents an overview of enabling technologies for efficient WEH, analyzes the lifetime of WEH-enabled IoT devices, and briefly study the future trends in the design of efficientWEH systems and research challenges that lie ahead.
Abstract: The Internet of Things (IoT) is an emerging computing concept that describes a structure in which everyday physical objects, each provided with unique identifiers, are connected to the Internet without requiring human interaction. Long-term and self-sustainable operation are key components for realization of such a complex network, and entail energy-aware devices that are potentially capable of harvesting their required energy from ambient sources. Among different energy harvesting methods, such as vibration, light, and thermal energy extraction, wireless energy harvesting (WEH) has proven to be one of the most promising solutions by virtue of its simplicity, ease of implementation, and availability. In this article, we present an overview of enabling technologies for efficient WEH, analyze the lifetime of WEH-enabled IoT devices, and briefly study the future trends in the design of efficient WEH systems and research challenges that lie ahead.

01 Jun 2015
TL;DR: The central finding is that the hype may actually understate the full potential of the IoT—but that capturing it will require an understanding of where real value can be created and a successful effort to address a set of systems issues, including interoperability.
Abstract: The Internet of Things (IoT)—sensors and actuators connected by networks to computing systems—has received enormous attention over the past five years. A new McKinsey Global Institute report, The Internet of Things: Mapping the value beyond the hype, attempts to determine exactly how IoT technology can create real economic value. Our central finding is that the hype may actually understate the full potential—but that capturing it will require an understanding of where real value can be created and a successful effort to address a set of systems issues, including interoperability. To get a broader view of the IoT’s potential benefits and challenges across the global economy, we analyzed more than 150 use cases, ranging from people whose devices monitor health and wellness to manufacturers that utilize sensors to optimize the maintenance of equipment and protect the safety of workers. Our bottom-up analysis for the applications we size estimates that the IoT has a total potential economic impact of $3.9 trillion to $11.1 trillion a year by 2025. At the top end, that level of value—including the consumer surplus—would be equivalent to about 11 percent of the world economy.

Posted Content
TL;DR: oTree is an open-source and online software for implementing interactive experiments in the laboratory, online, the field or combinations thereof, and provides the source code, a library of standard game templates and demo games which can be played by anyone.
Abstract: oTree is an open-source and online software for implementing interactive experiments in the laboratory, online, the field or combinations thereof. oTree does not require installation of software on subjects’ devices; it can run on any device that has a web browser, be that a desktop computer, a tablet or a smartphone. Deployment can be internet-based without a shared local network, or local-network-based even without internet access. For coding, Python is used, a popular, open-source programming language. www.oTree.org provides the source code, a library of standard game templates and demo games which can be played by anyone.

Journal ArticleDOI
TL;DR: This colloquium highlights the importance of pattern formation and collective behavior for the promotion of cooperation under adverse conditions, as well as the synergies between network science and evolutionary game theory.
Abstract: Networks form the backbone of many complex systems, ranging from the Internet to human societies. Accordingly, not only is the range of our interactions limited and thus best described and modeled by networks, it is also a fact that the networks that are an integral part of such models are often interdependent or even interconnected. Networks of networks or multilayer networks are therefore a more apt description of social systems. This colloquium is devoted to evolutionary games on multilayer networks, and in particular to the evolution of cooperation as one of the main pillars of modern human societies. We first give an overview of the most significant conceptual differences between single-layer and multilayer networks, and we provide basic definitions and a classification of the most commonly used terms. Subsequently, we review fascinating and counterintuitive evolutionary outcomes that emerge due to different types of interdependencies between otherwise independent populations. The focus is on coupling through the utilities of players, through the flow of information, as well as through the popularity of different strategies on different network layers. The colloquium highlights the importance of pattern formation and collective behavior for the promotion of cooperation under adverse conditions, as well as the synergies between network science and evolutionary game theory.

Journal ArticleDOI
TL;DR: Improvements to the resource and the set of tools available for interrogating and accessing BRC data are described including the integration of Web Apollo to facilitate community annotation and providing Galaxy to support user-based workflows.
Abstract: VectorBase is a National Institute of Allergy and Infectious Diseases supported Bioinformatics Resource Center (BRC) for invertebrate vectors of human pathogens Now in its 11th year, VectorBase currently hosts the genomes of 35 organisms including a number of non-vectors for comparative analysis Hosted data range from genome assemblies with annotated gene features, transcript and protein expression data to population genetics including variation and insecticide-resistance phenotypes Here we describe improvements to our resource and the set of tools available for interrogating and accessing BRC data including the integration of Web Apollo to facilitate community annotation and providing Galaxy to support user-based workflows VectorBase also actively supports our community through hands-on workshops and online tutorials All information and data are freely available from our website at https://wwwvectorbaseorg/

Journal ArticleDOI
TL;DR: The IoBNT stands as a paradigm-shifting concept for communication and network engineering, where novel challenges are faced to develop efficient and safe techniques for the exchange of information, interaction, and networking within the biochemical domain, while enabling an interface to the electrical domain of the Internet.
Abstract: The Internet of Things (IoT) has become an important research topic in the last decade, where things refer to interconnected machines and objects with embedded computing capabilities employed to extend the Internet to many application domains. While research and development continue for general IoT devices, there are many application domains where very tiny, concealable, and non-intrusive Things are needed. The properties of recently studied nanomaterials, such as graphene, have inspired the concept of Internet of NanoThings (IoNT), based on the interconnection of nanoscale devices. Despite being an enabler for many applications, the artificial nature of IoNT devices can be detrimental where the deployment of NanoThings could result in unwanted effects on health or pollution. The novel paradigm of the Internet of Bio-Nano Things (IoBNT) is introduced in this paper by stemming from synthetic biology and nanotechnology tools that allow the engineering of biological embedded computing devices. Based on biological cells, and their functionalities in the biochemical domain, Bio-NanoThings promise to enable applications such as intra-body sensing and actuation networks, and environmental control of toxic agents and pollution. The IoBNT stands as a paradigm-shifting concept for communication and network engineering, where novel challenges are faced to develop efficient and safe techniques for the exchange of information, interaction, and networking within the biochemical domain, while enabling an interface to the electrical domain of the Internet.

Journal ArticleDOI
Nick Hajli1
TL;DR: This research investigates the new stream in e-commerce by proposing a new model to develop understanding of social commerce using a PLS-SEM methodology and results show that Web 2.0 applications are attracting individuals to have interactions as well as generate content on the Internet.

Journal ArticleDOI
TL;DR: The current version of the Human Disease Ontology (DO), a biomedical resource of standardized common and rare disease concepts with stable identifiers organized by disease etiology, is moving to a multi-editor model utilizing Protégé to curate DO in web ontology language.
Abstract: The current version of the Human Disease Ontology (DO) (http://www.disease-ontology.org) database expands the utility of the ontology for the examination and comparison of genetic variation, phenotype, protein, drug and epitope data through the lens of human disease. DO is a biomedical resource of standardized common and rare disease concepts with stable identifiers organized by disease etiology. The content of DO has had 192 revisions since 2012, including the addition of 760 terms. Thirty-two percent of all terms now include definitions. DO has expanded the number and diversity of research communities and community members by 50+ during the past two years. These community members actively submit term requests, coordinate biomedical resource disease representation and provide expert curation guidance. Since the DO 2012 NAR paper, there have been hundreds of term requests and a steady increase in the number of DO listserv members, twitter followers and DO website usage. DO is moving to a multi-editor model utilizing Protege to curate DO in web ontology language. This will enable closer collaboration with the Human Phenotype Ontology, EBI's Ontology Working Group, Mouse Genome Informatics and the Monarch Initiative among others, and enhance DO's current asserted view and multiple inferred views through reasoning.

Proceedings ArticleDOI
01 Dec 2015
TL;DR: An overview of security principles, technological and security challenges, proposed countermeasures, and the future directions for securing the IoT is presented.
Abstract: The paper presents a survey and analysis on the current status and concerns of Internet of things (IoT) security. The IoT framework aspires to connect anyone with anything at anywhere. IoT typically has a three layers architecture consisting of Perception, Network, and Application layers. A number of security principles should be enforced at each layer to achieve a secure IoT realization. The future of IoT framework can only be ensured if the security issues associated with it are addressed and resolved. Many researchers have attempted to address the security concerns specific to IoT layers and devices by implementing corresponding countermeasures. This paper presents an overview of security principles, technological and security challenges, proposed countermeasures, and the future directions for securing the IoT.

Journal ArticleDOI
TL;DR: This introduction to a special issue of "Telecommunications Policy" entitled "The Governance of Social Media" begins with a definition of social media that informs all contributions in the special issue, and synthesize definitions presented in the literature.
Abstract: This introduction to a special issue of "Telecommunications Policy" entitled "The Governance of Social Media" begins with a definition of social media that informs all contributions in the special issue. A section describing the challenges associated with the governance of social media is presented next, followed by an overview of the various articles included in the special issue.While the Internet and the World Wide Web have always been used to facilitate social interaction, the emergence and rapid diffusion of Web 2.0 functionalities during the first decade of the new millennium enabled an evolutionary leap forward in the social component of web use. This and falling costs for online data storage made it feasible for the first time to offer masses of Internet users access to an array of user-centric spaces they could populate with user-generated content, along with a correspondingly diverse set of opportunities for linking these spaces together to form virtual social networks.To define “social media” for our current purposes, we synthesize definitions presented in the literature and identify the following commonalities among current social media services:1) Social media services are (currently) Web 2.0 Internet-based applications,2) User-generated content is the lifeblood of social media,3) Individuals and groups create user-specific profiles for a site or app designed and maintained by a social media service,4) Social media services facilitate the development of social networks online by connecting a profile with those of other individuals and/or groups.Transformative communication technologies have always called for regulatory innovation. Theodor Vail’s vision of “one policy, one system, universal service” preceded more than one-hundred years of innovative regulations aimed at connecting all Americans to a single telephone network. The sinking of the Titanic, caused in part by “chaos in the spectrum” led to the Radio Act of 1912 and the creation of a command and control model designed to regulate broadcast radio. Safe-harbor hours were put in place after a father and son heard George Carlin’s “seven dirty words” routine over the radio in their car. The fairness doctrine and the minority tax certificate program were designed to address inequalities in the broadcast television industry. The Digital Millennium Copyright Act responded to intellectual property concerns raised by a global Internet and the FCC’s 700mhz auction was the result of demand for smarter mobile phones. Now we must consider the role of regulatory innovation in response to the emergence of social media.

Journal ArticleDOI
TL;DR: This article positions visual computing in its intrinsic crucial role for Industrie 4.0 and provides a general, broad overview and points out specific directions and scenarios for future research.
Abstract: A worldwide movement in advanced manufacturing countries is seeking to reinvigorate (and revolutionize) the industrial and manufacturing core competencies with the use of the latest advances in information and communications technology. Visual computing plays an important role as the "glue factor" in complete solutions. This article positions visual computing in its intrinsic crucial role for Industrie 4.0 and provides a general, broad overview and points out specific directions and scenarios for future research.