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Simon C. Watkins

Researcher at University of Pittsburgh

Publications -  999
Citations -  75771

Simon C. Watkins is an academic researcher from University of Pittsburgh. The author has contributed to research in topics: Apoptosis & Immune system. The author has an hindex of 135, co-authored 950 publications receiving 68358 citations. Previous affiliations of Simon C. Watkins include Harvard University & Children's National Medical Center.

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An analytical study on heat transfer performance of radiators with non-uniform airflow distribution

TL;DR: In this article, a generalized analytical model accounting for airflow maldistribution was developed using a finite element approach and applying appropriate heat transfer equations including the epsilon-NTU (effectiveness - number of heat transfer units) method with the Davenport correlation for the air-side heat transfer coefficient.
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Dynamic properties of antigen uptake and communication between dendritic cells.

TL;DR: In this article, the authors examined mechanisms of antigen uptake by dendritic cells (DC) and showed that induced calcium fluxes in these cells could be propagated to other cells via thin membrane connections termed tunneling nanotubules that were shown to form an extensive network between cells.
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Purine nucleoside phosphorylase inhibition ameliorates age-associated lower urinary tract dysfunctions

TL;DR: It is demonstrated that 8-AG has translational potential for treating age-associated LUT dysfunctions and resultant syndromes in humans and is an effective treatment that ameliorates key age-related structural and physiologic bladder abnormalities.
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A study on the mechanism of phalloidin-induced tension changes in skinned rabbit psoas muscle fibres.

TL;DR: The data indicate that the decrease in tension caused by phalloidin was associated with binding of phaloidin to the pointed ends of actin filament and the Z-line region, whereas the increase in tension occurred when phalloidsin was bound along entire length of the actin filaments.
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Intestinal Microvascular Patterns During Hemorrhagic Shock

TL;DR: The observations suggest that the cryptal plexus is perfused preferentially during hemorrhagic shock, as a consequence of its peculiar microvascular organization, which may explain the relative resistance of the crypts, compared to villi, to hypoxic injuries in order to sustain endocrine function and the regenerative capability of the mucosa after prolonged hypoperfusion conditions.