S
Simon C. Watkins
Researcher at University of Pittsburgh
Publications - 999
Citations - 75771
Simon C. Watkins is an academic researcher from University of Pittsburgh. The author has contributed to research in topics: Apoptosis & Immune system. The author has an hindex of 135, co-authored 950 publications receiving 68358 citations. Previous affiliations of Simon C. Watkins include Harvard University & Children's National Medical Center.
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Journal ArticleDOI
Influence of the Novel ATP-Competitive Dual mTORC1/2 Inhibitor AZD2014 on Immune Cell Populations and Heart Allograft Rejection.
Daniel Fantus,Helong Dai,Helong Dai,Yoshihiro Ono,Alicia R. Watson,Shinichiro Yokota,Kanishka Mohib,Osamu Yoshida,Mark A. Ross,Simon C. Watkins,Bala Ramaswami,Anna Valusjkikh,David M. Rothstein,Angus W. Thomson +13 more
TL;DR: Investigation of the novel target of rapamycin kinase inhibitor AZD2014 found that it impaired dendritic cell differentiation and T cell proliferation in vitro and depressed immune cells and allospecific T cell responses in vivo, and immune cell populations in normal and heart allograft recipient mice were analyzed by flow cytometry.
Journal ArticleDOI
Ultrastructure of muscular dystrophy: New aspects
TL;DR: The increasing availability of both polyclonal and monoclonal antibodies has made possible the EM immunolabelling of dystrophin; immunogold on cryosections being the technique of choice.
Journal ArticleDOI
Correlations between transmural mechanical and morphological properties in porcine thoracic descending aorta
Ali Hemmasizadeh,Alkiviadis Tsamis,Rabee Cheheltani,Soroush Assari,Antonio D'Amore,Michael V. Autieri,Mohammad F. Kiani,Nancy Pleshko,William R. Wagner,Simon C. Watkins,David A. Vorp,Kurosh Darvish +11 more
TL;DR: The results of this study represent a substantial step toward anatomical characterization of the aortic wall building blocks and establishment of a foundation for quantifying the role of microstructural components on the functionality of aorta.
Proceedings ArticleDOI
Control strategies for flight in extreme turbulence
TL;DR: In this article, the authors study how the design of control law parameters a ects the attitude stability and path tracking accuracy of a single-wing UAV operating in extreme turbulence.
Proceedings ArticleDOI
Alterations in the Microstructure of the Anterior Mitral Valve Leaflet Under Physiological Stress
Christopher A. Carruthers,Bryan C. Good,Bryan C. Good,Antonio D'Amore,Jun Liao,Rouzbeh Amini,Simon C. Watkins,Michael S. Sacks +7 more
TL;DR: The goal was to quantitatively characterize the MV microstructure as a function of physiological loads, including localized 3D VIC deformations and relate it to the fiber network.