S
Simon C. Watkins
Researcher at University of Pittsburgh
Publications - 999
Citations - 75771
Simon C. Watkins is an academic researcher from University of Pittsburgh. The author has contributed to research in topics: Apoptosis & Immune system. The author has an hindex of 135, co-authored 950 publications receiving 68358 citations. Previous affiliations of Simon C. Watkins include Harvard University & Children's National Medical Center.
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Energy and cost analysis of a solar-hydrogen combined heat and power system for remote power supply using a computer simulation
TL;DR: In this paper, a simulation program based on Visual Pascal for sizing and techno-economic analysis of the performance of solar-hydrogen combined heat and power systems for remote applications is described, and the accuracy of the submodels is checked by comparing the real performances of the system's components obtained from experimental measurements with model outputs.
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Transient Fcho1/2⋅Eps15/R⋅AP-2 Nanoclusters Prime the AP-2 Clathrin Adaptor for Cargo Binding.
Li Ma,Perunthottathu K. Umasankar,A.G. Wrobel,Anastasia Lymar,Airlie J. McCoy,Sachin S. Holkar,Anupma Jha,Tirthadipa Pradhan-Sundd,Simon C. Watkins,David J. Owen,Linton M. Traub +10 more
TL;DR: It is established that without these two endocytic pioneers, AP-2 assemblies are fleeting and endocytosis stalls, and distinct DPF-based codes within the unstructured Eps15/R C terminus direct the assembly of temporary Fcho1/2⋅Eps 15/R ⋅AP-2 ternary complexes to facilitate conformational activation of AP-1 by the Fcho 1/2 interdomain linker to promote AP- 2 cargo engagement
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Identification of c-kit-positive cells in the mouse ureter: the interstitial cells of Cajal of the urinary tract.
Michael A. Pezzone,Simon C. Watkins,Sean Alber,William E. King,William C. de Groat,Michael B. Chancellor,Matthew O. Fraser +6 more
TL;DR: Like in the gut, c-kit-positive, ICC-like cells are present in the urinary tract but appear to be restricted to the proximal ureter of this murine species.
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Enhancement of head and neck squamous cell carcinoma proliferation, invasion, and metastasis by tumor-associated fibroblasts in preclinical models.
Sarah E Wheeler,Huifang Shi,Fangchen Lin,Sumana Dasari,Joseph S. Bednash,Stephen H. Thorne,Simon C. Watkins,Radhika Joshi,Sufi M. Thomas +8 more
TL;DR: In this paper, the effects of TAF-secreted paracrine factors on in vitro head and neck squamous cell carcinoma (HNSCC) migration, invasion, and proliferation were assessed.
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The Insulin Secretory Granule Is the Major Site of KATP Channels of the Endocrine Pancreas
TL;DR: The results demonstrate that the insulin secretory granule is the major site of K(ATP) channels of the endocrine pancreas, and two different K(ir)6.2 antibodies specifically label perimeter membrane regions of the secretorygranule.