S
Simon C. Watkins
Researcher at University of Pittsburgh
Publications - 999
Citations - 75771
Simon C. Watkins is an academic researcher from University of Pittsburgh. The author has contributed to research in topics: Apoptosis & Immune system. The author has an hindex of 135, co-authored 950 publications receiving 68358 citations. Previous affiliations of Simon C. Watkins include Harvard University & Children's National Medical Center.
Papers
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Journal ArticleDOI
Nrf2 deficiency in mice attenuates erythropoietic stress-related macrophage hypercellularity.
Oluwabukola T. Gbotosho,Maria G. Kapetanaki,Mark A. Ross,Samit Ghosh,Frances Weidert,Grant C. Bullock,Simon C. Watkins,Solomon F. Ofori-Acquah,Gregory J. Kato +8 more
TL;DR: The role of Nrf2 in stress erythropoiesis in the bone marrow is demonstrated and the finding of macrophage hypercellularity is confirmed, a previously underappreciated feature of stress eriesis in sickle cell disease and recovery from blood loss.
Journal ArticleDOI
Polysomes are associated with microtubules in fertilized eggs of Chinese pine ( Pinus tabulaeformis )
TL;DR: The polysomes are associated with microtubules (MTs) from fertilization to the 2-nucleate embryo stage and this association persisted until the formation of the polarized embryo.
Journal ArticleDOI
Massive volumetric imaging of cleared tissue: The necessary tools to be successful
Alan M. Watson,Simon C. Watkins +1 more
TL;DR: The tool sets that are available for cleared tissue imaging are discussed and how various choices may influence the planning and feasibility of an experiment are discussed.
Journal ArticleDOI
Lower respiratory tract myeloid cells harbor SARS-CoV-2 and display an inflammatory phenotype.
William Bain,Hernán F. Peñaloza,Mark S. Ladinsky,Rick van der Geest,Mara Sullivan,Mark A. Ross,Georgios D Kitsios,Barbara Methé,Bryan J. McVerry,Alison Morris,Alan M. Watson,Simon C. Watkins,Claudette M. St. Croix,Donna B. Stolz,Pamela J. Bjorkman,Janet S. Lee +15 more
TL;DR: Endotracheal aspirates from seven patients with SARS-CoV-2 pneumonia requiring mechanical ventilation are described, finding that these myeloid cells that harbor virus are frequently positive for CD14 and/or CD16 and most display an inflammatory phenotype marked by expression of IL-6 and tissue factor mRNA transcript and protein expression.
Aerodynamic strategy applied in an urban shelter design - Simulation and analysis of aerodynamic phenomena in an urban context
TL;DR: In this paper, the reconfiguration and projection of wind patterns to produce vaults of wind as regions of shelter in the outdoor environment is discussed. But the authors focus on the use of porous membranes to improve the mitigation level of wind speed and turbulence intensity in the wind vaults.