S
Simon C. Watkins
Researcher at University of Pittsburgh
Publications - 999
Citations - 75771
Simon C. Watkins is an academic researcher from University of Pittsburgh. The author has contributed to research in topics: Apoptosis & Immune system. The author has an hindex of 135, co-authored 950 publications receiving 68358 citations. Previous affiliations of Simon C. Watkins include Harvard University & Children's National Medical Center.
Papers
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Proceedings ArticleDOI
Numerical investigation on the efficiency of a plasma actuator for turbine applications
TL;DR: In this paper, a numerical plasma model via steady-state RANS turbulence modeling simulations was developed for axial turbine engines, and reasonable agreement has been observed in the calibration of the numerical model to experimental data.
Book ChapterDOI
Energy Harvesting from Flows Using Piezoelectric Patches
TL;DR: The highly nonlinear phenomenon of fluid-structure interaction is discussed in this paper, including examples drawn from nature and early work on aircraft flutter, and the practical implications of such systems in the future are discussed.
Journal ArticleDOI
Discovering selective antiferroptotic inhibitors of the 15LOX/PEBP1 complex noninterfering with biosynthesis of lipid mediators.
Haider H. Dar,Karolina Mikulska-Ruminska,Yulia Y. Tyurina,Diane K. Luci,Adam Yasgar,S. N. Samovich,Alexandr A. Kapralov,Austin B. Souryavong,Vladimir A. Tyurin,Andrew A. Amoscato,Michael W. Epperly,Galina V. Shurin,Melissa Standley,Theodore R. Holman,Claudette M. St. Croix,Simon C. Watkins,Andrew P. VanDemark,Sandeep Kumar Rana,Alexey V. Zakharov,Anton Simeonov,Juan Marugan,Rama K. Mallampalli,Sally E. Wenzel,Joel S. Greenberger,Ganesha Rai,Hülya Bayır,Ivet Bahar,Valerian E. Kagan +27 more
TL;DR: In this article , the authors proposed a strategy of discovering antiferroptotic agents as inhibitors of the 15LOX/PEBP1 catalytic complex rather than 15 LOX alone.
Posted ContentDOI
Enhancing acute kidney injury regeneration by promoting cellular dedifferentiation in zebrafish
Lauren Brilli Skvarca,Hwa In Han,Eugenel B. Espiritu,Maria A. Missinato,Elizabeth R. Rochon,Michael D. McDaniels,Beth L. Roman,Joshua S. Waxman,Simon C. Watkins,Alan J. Davidson,Michael Tsang,Neil A. Hukriede +11 more
TL;DR: Investigating the regenerative mechanisms of PTBA in zebrafish models of larval renal injury and adult cardiac injury provides key mechanistic insights into how PTBA enhances tissue repair in models of acute injury and lays the groundwork for translating this novel HDI into the clinic.
Journal ArticleDOI
UV-DDB stimulates the activity of SMUG1 during base excision repair of 5-hydroxymethyl-2'-deoxyuridine moieties
Sunbok Jang,Sripriya J Raja,Vera Roginskaya,M.A. Schaich,Simon C. Watkins,Bennett Van Houten +5 more
TL;DR: In this paper, a non-canonical role for UV-damaged DNA-binding protein (UV-DDB) in the processing of 8-oxoG, by stimulating OGG1, activity 3-fold, MUTYH activity 4-5-fold and APE1 activity 8-fold.