Simon C. Watkins

TL;DR: It is suggested that one function of the CX3CR1-CX3CL1 pathway is to recruit and sustain divergent immune cell populations implicated in the pathogenesis of cigarette smoke-induced emphysema.

TL;DR: The basic technology inherent to all confocal microscopes, the applications in which the confocal is an essential tool, with particular attention to the specialized use of confocal systems with in vivo preparations, are discussed and a limited comparison of the applications of specific subtypes of conf focal microscopes is provided.

TL;DR: Using atomic force microscopy and single molecule fluorescence microscopy, it is demonstrated that PARP inhibitor olaparib did not significantly alter the rate of PARP1 dissociation from DNA, but instead resulted in more motility of DNA-boundPARP1 molecules.

TL;DR: In this paper, existing data from meteorologists and wind engineers are reviewed and measurements dedicated to understanding the spatial and temporal velocity fields that MAVs experience are briefly described Data from a wide variety of terrains are analysed, with the majority of data obtained in relatively well mixed turbulent flow and for conditions of nominally neutral stability Spectra for data well removed from local effects exhibited the expected 5/3rds Kolmogorov law.

TL;DR: The results suggest that proapoptotic peptides and, in particular, DP2 can be clinically useful for treatment of synovial hyperplasia, as well as inflammation.