Institution
Hokkaido University
Education•Sapporo, Hokkaidô, Japan•
About: Hokkaido University is a education organization based out in Sapporo, Hokkaidô, Japan. It is known for research contribution in the topics: Catalysis & Population. The organization has 53925 authors who have published 115403 publications receiving 2651647 citations. The organization is also known as: Hokudai & Hokkaidō daigaku.
Topics: Catalysis, Population, Gene, Virus, Oxide
Papers published on a yearly basis
Papers
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TL;DR: Circumpolar Deep Water has been warming and moving further up onto the shelf around Antarctica for the past 40 years, causing higher rates of ice sheet melting, which need to be taken into account when considering the potential for irreversible retreat of parts of the West Antarctic Ice Sheet.
Abstract: Decadal trends in the properties of seawater adjacent to Antarctica are poorly known, and the mechanisms responsible for such changes are uncertain. Antarctic ice sheet mass loss is largely driven by ice shelf basal melt, which is influenced by ocean-ice interactions and has been correlated with Antarctic Continental Shelf Bottom Water (ASBW) temperature. We document the spatial distribution of long-term large-scale trends in temperature, salinity, and core depth over the Antarctic continental shelf and slope. Warming at the seabed in the Bellingshausen and Amundsen seas is linked to increased heat content and to a shoaling of the mid-depth temperature maximum over the continental slope, allowing warmer, saltier water greater access to the shelf in recent years. Regions of ASBW warming are those exhibiting increased ice shelf melt.
359 citations
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TL;DR: Results indicate that classification based on the DNA methylation profiles of CpG I of the BDNF gene may be a valuable diagnostic biomarker for major depression.
Abstract: Major depression, because of its recurring and life-threatening nature, is one of the top 10 diseases for global disease burden. Major depression is still diagnosed on the basis of clinical symptoms in patients. The search for specific biological markers is of great importance to advance the method of diagnosis for depression. We examined the methylation profile of 2 CpG islands (I and IV) at the promoters of the brain-derived neurotrophic factor (BDNF) gene, which is well known to be involved in the pathophysiology of depression. We analyzed genomic DNA from peripheral blood of 20 Japanese patients with major depression and 18 healthy controls to identify an appropriate epigenetic biomarker to aid in the establishment of an objective system for the diagnosis of depression. Methylation rates at each CpG unit was measured using a MassArray® system (SEQUENOM), and 2-dimensional hierarchical clustering analyses were undertaken to determine the validity of these methylation profiles as a diagnostic biomarker. Analyses of the dendrogram from methylation profiles of CpG I, but not IV, demonstrated that classification of healthy controls and patients at the first branch completely matched the clinical diagnosis. Despite the small number of subjects, our results indicate that classification based on the DNA methylation profiles of CpG I of the BDNF gene may be a valuable diagnostic biomarker for major depression.
358 citations
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TL;DR: It is revealed that the amine functionality in NH2–MIL‐88B (Fe) can also be excited and then transferred an electron to Fe3‐μ3‐oxo clusters, which is responsible for the enhanced photocatalytic activity for Cr(VI) reduction.
Abstract: The photocatalytic reduction of Cr(VI) is investigated over iron(III)-based metal-organic frameworks (MOFs) structured as MIL-88B. It is found that MIL-88B (Fe) MOFs, containing Fe3-μ3-oxo clusters, can be used as photocatalyst for the reduction of Cr(VI) under visible light irradiation, which is due to the direct excitation of Fe3-μ3-oxo clusters. The amine-functionalized MIL-88B (Fe) MOFs (denoted as NH2-MIL-88B (Fe)) shows much higher efficiency for the photocatalytic Cr(VI) reduction under visible-light irradiation compared with MIL-88B (Fe). It is revealed that in addition to the direct excitation of Fe3-μ3-oxo clusters, the amine functionality in NH2-MIL-88B (Fe) can also be excited and then transferred an electron to Fe3-μ3-oxo clusters, which is responsible for the enhanced photocatalytic activity for Cr(VI) reduction. The enhanced photocatalytic activity for Cr(VI) reduction is also achieved for other two amine-functionalized iron(III)-based MOFs (NH2-MIL-53 (Fe) and NH2-MIL-101 (Fe)).
358 citations
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TL;DR: An analysis of decomposition of methylene blue in an aerated aqueous solution by its action spectrum has shown that sulfur-doped titania (S-TiO 2 ) has activity under visible-light irradiation and that the decomposition mechanism depends on the excitation wavelength as discussed by the authors.
358 citations
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TL;DR: The most plausible number of infections is in the order of thousands, rather than hundreds, and there is a strong indication that untraced exposures other than the one in the epidemiologically linked seafood market in Wuhan have occurred.
Abstract: A cluster of pneumonia cases linked to a novel coronavirus (2019-nCoV) was reported by China in late December 2019. Reported case incidence has now reached the hundreds, but this is likely an underestimate. As of 24 January 2020, with reports of thirteen exportation events, we estimate the cumulative incidence in China at 5502 cases (95% confidence interval: 3027, 9057). The most plausible number of infections is in the order of thousands, rather than hundreds, and there is a strong indication that untraced exposures other than the one in the epidemiologically linked seafood market in Wuhan have occurred.
358 citations
Authors
Showing all 54156 results
Name | H-index | Papers | Citations |
---|---|---|---|
Shizuo Akira | 261 | 1308 | 320561 |
Yi Cui | 220 | 1015 | 199725 |
John F. Hartwig | 145 | 714 | 66472 |
Yoshihiro Kawaoka | 139 | 883 | 75087 |
David Y. Graham | 138 | 1047 | 80886 |
Takashi Kadowaki | 137 | 873 | 89729 |
Kazunari Domen | 130 | 908 | 77964 |
Susumu Kitagawa | 125 | 809 | 69594 |
Toshikazu Nakamura | 121 | 732 | 51374 |
Toshio Hirano | 120 | 401 | 55721 |
Li-Jun Wan | 113 | 639 | 52128 |
Wenbin Lin | 113 | 474 | 56786 |
Xiaoming Li | 113 | 1932 | 72445 |
Jinhua Ye | 112 | 658 | 49496 |
Terence Tao | 111 | 606 | 94316 |