Institution
Hokkaido University
Education•Sapporo, Hokkaidô, Japan•
About: Hokkaido University is a education organization based out in Sapporo, Hokkaidô, Japan. It is known for research contribution in the topics: Catalysis & Population. The organization has 53925 authors who have published 115403 publications receiving 2651647 citations. The organization is also known as: Hokudai & Hokkaidō daigaku.
Topics: Catalysis, Population, Gene, Virus, Oxide
Papers published on a yearly basis
Papers
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TL;DR: This review honoring Jobsis highlights the progress that has been made in developing and adapting NIRS and NIR imaging (NIRI) technologies for evaluating skeletal muscle O(2) dynamics and oxidative energy metabolism.
Abstract: Near-infrared spectroscopy (NIRS) was initiated in 1977 by Jobsis as a simple, noninvasive method for measuring the presence of oxygen in muscle and other tissues in vivo. This review honoring Jobsis highlights the progress that has been made in developing and adapting NIRS and NIR imaging (NIRI) technologies for evaluating skeletal muscle O(2) dynamics and oxidative energy metabolism. Development of NIRS/NIRI technologies has included novel approaches to quantification of the signal, as well as the addition of multiple source detector pairs for imaging. Adaptation of NIRS technology has focused on the validity and reliability of NIRS measurements. NIRS measurements have been extended to resting, ischemic, localized exercise, and whole body exercise conditions. In addition, NIRS technology has been applied to the study of a number of chronic health conditions, including patients with chronic heart failure, peripheral vascular disease, chronic obstructive pulmonary disease, varying muscle diseases, spinal cord injury, and renal failure. As NIRS technology continues to evolve, the study of skeletal muscle function with NIRS first illuminated by Jobsis continues to be bright.
583 citations
TL;DR: Islet-activating protein (IAP), pertussis toxin, catalyses the transfer of the ADP-ribose moiety of NAD to the active subunit of N u resulting in a complete loss of the N i functions, which will be useful as a tool for further studies of the transmembrane signal transduction mechanism.
583 citations
TL;DR: The analysis of the antigenic and biological properties of the H5N1 influenza viruses isolated from chickens, ducks, and geese from farms and poultry markets in Hong Kong during 1997 and compares them with those of virus isolated from the index human case revealed limited antigenic drift in 15 years.
580 citations
TL;DR: Northern blot analysis and in situ hybridization indicate that these transporters are expressed predominantly in kidney with an intrarenal distribution consistent with their recognized functional localization, establishing a new family of Na(+)-(K+)-Cl- cotransporters.
580 citations
TL;DR: The development and applications of MEND are described, and strategies for overcoming the PEG dilemma are discussed, based on the manipulation of intracellular trafficking of cellular uptake and endosomal release using functional devices such as specific ligands, cleavable PEG systems andendosomal fusogenic/disruptic peptides.
579 citations
Authors
Showing all 54156 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| Shizuo Akira | 261 | 1308 | 320561 |
| Yi Cui | 220 | 1015 | 199725 |
| John F. Hartwig | 145 | 714 | 66472 |
| Yoshihiro Kawaoka | 139 | 883 | 75087 |
| David Y. Graham | 138 | 1047 | 80886 |
| Takashi Kadowaki | 137 | 873 | 89729 |
| Kazunari Domen | 130 | 908 | 77964 |
| Susumu Kitagawa | 125 | 809 | 69594 |
| Toshikazu Nakamura | 121 | 732 | 51374 |
| Toshio Hirano | 120 | 401 | 55721 |
| Li-Jun Wan | 113 | 639 | 52128 |
| Wenbin Lin | 113 | 474 | 56786 |
| Xiaoming Li | 113 | 1932 | 72445 |
| Jinhua Ye | 112 | 658 | 49496 |
| Terence Tao | 111 | 606 | 94316 |