Institution
Kumamoto University
Education•Kumamoto, Kumamoto, Japan•
About: Kumamoto University is a education organization based out in Kumamoto, Kumamoto, Japan. It is known for research contribution in the topics: Cancer & Population. The organization has 19602 authors who have published 35513 publications receiving 901260 citations. The organization is also known as: Kumamoto Daigaku.
Topics: Cancer, Population, Gene, Cell culture, Receptor
Papers published on a yearly basis
Papers
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TL;DR: In this paper, a neural network based maximum power tracking controller for interconnected PV power systems is presented, where the neural network is utilized to identify the optimal operating voltage of the PV power system.
Abstract: This paper presents a neural network based maximum power tracking controller for interconnected PV power systems The neural network is utilized to identify the optimal operating voltage of the PV power system The controller generates the control signal in real-time, and the control signal is fed back to the voltage control loop of the inverter to shift the terminal voltage of the PV power system to its identified optimum, which yields maximum power generation The controller is of the PI type The proportional and the integral gains are set to their optimal values to achieve fast response and also to prevent overshoot and also undershoot Continuous measurement is required for the open circuit voltage on the monitoring cell, and also for the terminal voltage of the PV power system Because of the accurate identification of the optimal operating voltage of the PV power system, more than 99% power is drawn from the actual maximum power >
176 citations
TL;DR: AGE proteins, as ligands for SR-BI, effectively inhibit bothSR-BI-mediated selective uptake of HDL-CE and cholesterol efflux from peripheral cells to HDL, suggesting that AGE proteins might modulate SR- BI-mediated cholesterol metabolism in vivo.
176 citations
Boston Children's Hospital1, Necker-Enfants Malades Hospital2, First Faculty of Medicine, Charles University in Prague3, University of Zagreb4, Innsbruck Medical University5, Copenhagen University Hospital6, Children's National Medical Center7, Vrije Universiteit Brussel8, Great Ormond Street Hospital9, Kumamoto University10, University of Paris11, Université catholique de Louvain12, St Thomas' Hospital13, Manchester Academic Health Science Centre14, Erasmus University Rotterdam15
TL;DR: Neurologic impairment is common in OAD and UCD, whereas the involvement of other organs follows a disease-specific pattern, and the identification of unexpected chronic renal failure in GA1 and ASL deficiency emphasizes the importance of a systematic follow-up in patients with rare diseases.
Abstract: Background
The disease course and long-term outcome of patients with organic acidurias (OAD) and urea cycle disorders (UCD) are incompletely understood.
176 citations
TL;DR: In this article, the authors investigated the relationship between meteorological elements and green distribution in an urban area and found that air temperature distribution is closely related to the distribution of green covering and even a small green area of about 60 m × 40 m indicates the cooling effect.
175 citations
TL;DR: The data indicate that ZO-1 plays crucial roles not only in TJ formation, but also in the conversion from “fibroblastic’ AJs to belt-like “polarized epithelial” AJs through Rac1 activation, which suggests that Z O-1 is directly involved in the establishment of two distinct junctional domains, belt- like AJs and TJs, during epithelial polarization.
Abstract: The molecular mechanisms of how primordial adherens junctions (AJs) evolve into spatially separated belt-like AJs and tight junctions (TJs) during epithelial polarization are not well understood Previously, we reported the establishment of ZO-1/ZO-2–deficient cultured epithelial cells (1[ko]/2[kd] cells), which lacked TJs completely In the present study, we found that the formation of belt-like AJs was significantly delayed in 1(ko)/2(kd) cells during epithelial polarization The activation of Rac1 upon primordial AJ formation is severely impaired in 1(ko)/2(kd) cells Our data indicate that ZO-1 plays crucial roles not only in TJ formation, but also in the conversion from “fibroblastic” AJs to belt-like “polarized epithelial” AJs through Rac1 activation Furthermore, to examine whether ZO-1 itself mediate belt-like AJ and TJ formation, respectively, we performed a mutational analysis of ZO-1 The requirement for ZO-1 differs between belt-like AJ and TJ formation We propose that ZO-1 is directly involved in the establishment of two distinct junctional domains, belt-like AJs and TJs, during epithelial polarization
175 citations
Authors
Showing all 19645 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| Fred H. Gage | 216 | 967 | 185732 |
| George D. Yancopoulos | 158 | 496 | 93955 |
| Kenji Kangawa | 153 | 1117 | 110059 |
| Tasuku Honjo | 141 | 712 | 88428 |
| Hideo Yagita | 137 | 946 | 70623 |
| Masashi Yanagisawa | 130 | 524 | 83631 |
| Kazuwa Nakao | 128 | 1041 | 70812 |
| Kouji Matsushima | 124 | 590 | 56995 |
| Thomas E. Mallouk | 122 | 549 | 52593 |
| Toshio Hirano | 120 | 401 | 55721 |
| Eisuke Nishida | 112 | 349 | 45918 |
| Hiroaki Shimokawa | 111 | 949 | 48822 |
| Bernd Bukau | 111 | 271 | 38446 |
| Kazuo Tsubota | 105 | 1379 | 48991 |
| Toshio Suda | 104 | 580 | 41069 |