University of Turku

About: University of Turku is a education organization based out in Turku, Finland. It is known for research contribution in the topics: Population & Galaxy. The organization has 16296 authors who have published 45124 publications receiving 1505428 citations. The organization is also known as: Turun yliopisto & Åbo universitet.

Planet Hunters IX. KIC 8462852-where's the flux?

Abstract: TSB acknowledges support provided through NASA grant ADAP12-0172 and ADAP14-0245. MCW and GMK acknowledge the support of the European Union through ERC grant number 279973. The authors acknowledge support from the Hungarian Research Grants OTKA K-109276, OTKA K-113117, the Lendulet-2009 and Lendulet-2012 Program (LP2012-31) of the Hungarian Academy of Sciences, the Hungarian National Research, Development and Innovation Office – NKFIH K-115709, and the ESA PECS Contract No. 4000110889/14/NL/NDe. This work was supported by the Momentum grant of the MTA CSFK Lendulet Disc Research Group. GH acknowledges support by the Polish NCN grant 2011/01/B/ST9/05448. Based on observations made with the NOT, operated by the Nordic Optical Telescope Scientific Association at the Observatorio del Roque de los Muchachos, La Palma, Spain, of the Instituto de Astrofisica de Canarias. This research made use of The DASCH project; we are also grateful for partial support from NSF grants AST-0407380, AST-0909073, and AST-1313370. The research leading to these results has received funding from the European Community's Seventh Framework Programme (FP7/2007-2013) under grant agreements no. 269194 (IRSES/ASK) and no. 312844 (SPACEINN). We thank Scott Dahm, Julie Rivera, and the Keck Observatory staff for their assistance with these observations. This research was supported in part by NSF grant AST-0909222 awarded to M. Liu. The authors wish to recognize and acknowledge the very significant cultural role and reverence that the summit of Mauna Kea has always had within the indigenous Hawaiian community. We are most fortunate to have the opportunity to conduct observations from this mountain. KS gratefully acknowledges support from Swiss National Science Foundation Grant PP00P2_138979/1. HJD and DN acknowledge support by grant AYA2012-39346-C02-02 of the Spanish Secretary of State for R&D&i (MINECO). This paper makes use of data from the first public release of the WASP data (Butters et al. 2010) as provided by the WASP consortium and services at the NASA Exoplanet Archive, which is operated by the California Institute of Technology, under contract with the National Aeronautics and Space Administration under the Exoplanet Exploration Program. This publication makes use of data products from the Wide-field Infrared Survey Explorer, which is a joint project of the University of California, Los Angeles, and the Jet Propulsion Laboratory/California Institute of Technology, and NEOWISE, which is a project of the Jet Propulsion Laboratory/California Institute of Technology. WISE and NEOWISE are funded by the National Aeronautics and Space Administration. This research made use of the SIMBAD and VIZIER Astronomical Databases, operated at CDS, Strasbourg, France (http://cdsweb.u-strasbg.fr/), and of NASA's Astrophysics Data System.

Guidance for substantiating the evidence for beneficial effects of probiotics: prevention and management of infections by probiotics.

Abstract: Allergy is a hypersensitivity reaction mediated by specific antibody-mediated or cell-mediated immunologic mechanisms and clinically manifested as atopic eczema, allergic rhinoconjunctivitis, or asthma. During the recent decades there has been an increase in allergy prevalence, which is attributed to changes in environmental factors. The so-called "hygiene hypothesis" suggests that a lack of exposure to microbial stimulus early in childhood is a major factor involved in this trend. This provides a rationale for using probiotics to modify the gut microbiota and thereby shaping the immune response of the host, especially in infancy. Most success has been obtained in primary prevention of atopic eczema. A limited number of studies also provided evidence for a beneficial effect of different probiotics in the management of allergic diseases (atopic eczema, allergic rhinitis). However, choice of probiotic strains as well as timing of the intervention are important variables. The exact in vivo mechanism of probiotics in shaping the immune response still needs to be determined. Future studies should use uniform criteria for diagnosis and symptom scoring of atopic diseases and may identify the genes predisposing to allergic disease. There is encouraging evidence that specific probiotics can become valuable tools in the prevention and management of allergic diseases.

Electroencephalogram spindle activity during dexmedetomidine sedation and physiological sleep

Abstract: Background: Dexmedetomidine, a selective α2-adrenoceptor agonist, induces a unique, sleep-like state of sedation. The objective of the present work was to study human electroencephalogram (EEG) sleep spindles during dexmedetomidine sedation and compare them with spindles during normal physiological sleep, to test the hypothesis that dexmedetomidine exerts its effects via normal sleep-promoting pathways. Methods: EEG was continuously recorded from a bipolar frontopolar–laterofrontal derivation with Entropy Module (GE Healthcare) during light and deep dexmedetomidine sedation (target-controlled infusions set at 0.5 and 3.2 ng/ml) in 11 healthy subjects, and during physiological sleep in 10 healthy control subjects. Sleep spindles were visually scored and quantitatively analyzed for density, duration, amplitude (band-pass filtering) and frequency content (matching pursuit approach), and compared between the two groups. Results: In visual analysis, EEG activity during dexmedetomidine sedation was similar to physiological stage 2 (S2) sleep with slight to moderate amount of slow-wave activity and abundant sleep spindle activity. In quantitative EEG analyses, sleep spindles were similar during dexmedetomidine sedation and normal sleep. No statistically significant differences were found in spindle density, amplitude or frequency content, but the spindles during dexmedetomidine sedation had longer duration (mean 1.11 s, SD 0.14 s) than spindles in normal sleep (mean 0.88 s, SD 0.14 s; P=0.0014). Conclusions: Analysis of sleep spindles shows that dexmedetomidine produces a state closely resembling physiological S2 sleep in humans, which gives further support to earlier experimental evidence for activation of normal non-rapid eye movement sleep-promoting pathways by this sedative agent.

Regional analysis of FDG and PIB-PET images in normal aging, mild cognitive impairment, and Alzheimer’s disease

Abstract: Objective The objective of the study is to compare the diagnostic value of regional sampling of the cerebral metabolic rate of glucose metabolism (MRglc) using [18F]-fluoro-2-deoxyglucose ([18F]FDG)-positron emission tomography (PET) and amyloid-beta pathology using Pittsburgh Compound-B ([11C]PIB)-PET in the evaluation of patients with Alzheimer’s disease (AD) and mild cognitive impairment (MCI) compared to normal elderly (NL)

Illocutionary Logic and Strands of Securitization: Applying the Theory of Securitization to the Study of Non-Democratic Political Orders:

Abstract: Convincing research programmes often use a variety of data from cases in different contexts; in order to reach a wider understanding, the models and hypothesis of securitization studies have to be applied to broad groups of cases. The research programme of securitization studies is formed around the leading idea of securitization being a social process achieved through speech acts. I argue that by explicating the concept of securitization through illocutionary logic, it can be utilized to study security politics in non-democratic contexts in addition to the favoured liberal democratic one, where the majority of empirical analysis has been conducted so far. In addition, I present clarifications to the concepts of 'audiences' and 'special politics' used in the theory. The theoretical discussion is illustrated with examples from the Chinese political system.