Identification of a novel coronavirus causing severe pneumonia in human: a descriptive study.
Lili Ren,Ye Ming Wang,Zhiqiang Wu,Zi Chun Xiang,Li Guo,Teng Xu,Yong Zhong Jiang,Yan Xiong,Li Yongjun,Xing Wang Li,Hui Li,Guo Hui Fan,Guo Hui Fan,Xiao Ying Gu,Xiao Ying Gu,Yan Xiao,Hong Gao,Jiu Yang Xu,Fan Yang,Xinming Wang,Chao Wu,Lan Chen,Yi Wei Liu,Bo Liu,Jian Yang,Xiao Rui Wang,Jie Dong,Li Li,Chao Lin Huang,Jian Ping Zhao,Yi Hu,Zhen Shun Cheng,Lin Lin Liu,Zhao Hui Qian,Chuan Qin,Qi Jin,Bin Cao,Bin Cao,Jianwei Wang +38 more
TLDR
A novel bat-borne CoV was identified that is associated with severe and fatal respiratory disease in humans and the amino acid sequence of the tentative receptor-binding domain resembles that of SARS-CoV, indicating that these viruses might use the same receptor.Citations
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The risk of intrauterine exposure to SARS‐CoV‐2 in female COVID‐19 patients: A comprehensive review
TL;DR: The immune response induced by SARS‐CoV‐2 in patients and the changes in ACE2 expression in the female reproductive system are summarized and the present observational evidence of infection in pregnant women was reviewed.
Journal ArticleDOI
Effectiveness of a digital data gathering system to manage the first pandemic wave among healthcare workers in a main European coronavirus disease 2019 (COVID-19) tertiary-care hospital
Emanuele Sansone,Emma Sala,Elisa Albini,Mara Maria Tiraboschi,Lorenzo Cipriani,Giuseppe De Palma +5 more
TL;DR: The data demonstrate the advantages of a digital system to gather information from workers, which is useful for managing emergencies such as the COVID-19 pandemic, and holds particularly true for large organizations such as hospitals.
Journal ArticleDOI
Sputnik Light and Sputnik V Vaccination Is Effective at Protecting Medical Personnel from COVID-19 during the Period of Delta Variant Dominance
Gennady T. Sukhikh,T. V. Priputnevich,Darya A. Ogarkova,Andrei A. Pochtovyi,Daria D. Kustova,Vladimir I. Zlobin,Denis Y. Logunov,Vladimir A. Gushchin,Alexander L. Gintsburg +8 more
TL;DR: A study of the effectiveness of vaccine use to protect medical workers at a large medical center for obstetrics and gynecology in Moscow found that the severity of COVID-19 in the vaccinated group was significantly lower than in the unvaccinated group.
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Voice from China: nomenclature of the novel coronavirus and related diseases
Gui-Zhen Wu,Jian-Wei Wang +1 more
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Whole Genome Comparison of Pakistani Corona Virus with Chinese and US Strains along with its Predictive Severity of COVID-19
TL;DR: 31 novel variants are identified in both Pakistani strains, assumed to be linked with reduced mortality of COVID-19 in Pakistan along with other influencing factors, these novel variants would also be useful to understand the virulence of this virus and to develop indigenous vaccines and therapeutics.
References
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Fast and accurate short read alignment with Burrows–Wheeler transform
Heng Li,Richard Durbin +1 more
TL;DR: Burrows-Wheeler Alignment tool (BWA) is implemented, a new read alignment package that is based on backward search with Burrows–Wheeler Transform (BWT), to efficiently align short sequencing reads against a large reference sequence such as the human genome, allowing mismatches and gaps.
Journal ArticleDOI
Trimmomatic: a flexible trimmer for Illumina sequence data
TL;DR: Timmomatic is developed as a more flexible and efficient preprocessing tool, which could correctly handle paired-end data and is shown to produce output that is at least competitive with, and in many cases superior to, that produced by other tools, in all scenarios tested.
Journal ArticleDOI
Isolation of a Novel Coronavirus from a Man with Pneumonia in Saudi Arabia
Ali Moh Zaki,Sander van Boheemen,Theo M. Bestebroer,Albert D. M. E. Osterhaus,Ron A. M. Fouchier +4 more
TL;DR: The clinical picture was remarkably similar to that of the severe acute respiratory syndrome (SARS) outbreak in 2003 and reminds us that animal coronaviruses can cause severe disease in humans.
Journal ArticleDOI
Origin and evolution of pathogenic coronaviruses
Jie Cui,Fang Li,Zhengli Shi +2 more
TL;DR: The viral factors that enabled the emergence of diseases such as severe acute respiratory syndrome and Middle East respiratory syndrome are explored and the diversity and potential of bat-borne coronaviruses are highlighted.
Journal ArticleDOI
SARS and MERS: recent insights into emerging coronaviruses
TL;DR: The emergence of Middle East respiratory syndrome coronavirus (MERS-CoV) in 2012 marked the second introduction of a highly pathogenic coronav virus into the human population in the twenty-first century, and the current state of development of measures to combat emerging coronaviruses is discussed.
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