Identification of a novel coronavirus causing severe pneumonia in human: a descriptive study.
Lili Ren,Ye Ming Wang,Zhiqiang Wu,Zi Chun Xiang,Li Guo,Teng Xu,Yong Zhong Jiang,Yan Xiong,Li Yongjun,Xing Wang Li,Hui Li,Guo Hui Fan,Guo Hui Fan,Xiao Ying Gu,Xiao Ying Gu,Yan Xiao,Hong Gao,Jiu Yang Xu,Fan Yang,Xinming Wang,Chao Wu,Lan Chen,Yi Wei Liu,Bo Liu,Jian Yang,Xiao Rui Wang,Jie Dong,Li Li,Chao Lin Huang,Jian Ping Zhao,Yi Hu,Zhen Shun Cheng,Lin Lin Liu,Zhao Hui Qian,Chuan Qin,Qi Jin,Bin Cao,Bin Cao,Jianwei Wang +38 more
TLDR
A novel bat-borne CoV was identified that is associated with severe and fatal respiratory disease in humans and the amino acid sequence of the tentative receptor-binding domain resembles that of SARS-CoV, indicating that these viruses might use the same receptor.Citations
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Perfil epidemiológico e clínico de pacientes com Covid-19 em uma Unidade de Terapia Intensiva de um hospital público de Teresina-PI
Brena Costa de Oliveira,Francelly Carvalho dos Santos,Hengrid Graciely Nascimento Silva,Isione Oliveira Castro,Vinicius de Sá Patricio Franco,Cibelle de Sousa e Silva,Samara Martins de Oliveira Souza,Valéria Monteiro Beserra da Silva,Letícia Graziela Lopes França,Luana Gabrielle de França Ferreira +9 more
TL;DR: In this article, the epidemiological and clinical profile of patients with COVID-19 admitted to the ICU of a public hospital in Teresina-PI was analyzed by analyzing medical records.
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Dietary guidelines to boost immunity during pre and post covid-19 conditions
Mahwish,Farhan Saeed,Muhammad Afzaal,Muzzamal Hussain,Muhammad Imran,Taufiq Nawaz,Azhari Siddeeg +6 more
TL;DR: In this article , a review summarizes the evidence-based literature for immuno-modulation and antiviral activity of different vitamins (A, B, C, D, E), omega-3 fatty acids, selenium, zinc and flavonoids.
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COVID-19 among staff and their family members of a healthcare research institution in Bangladesh between March 2020 and April 2021: a test-negative case–control study
Mustafa Mahfuz,Md. Ashraful Alam,Shah Mohammad Fahim,S. M. Tafsir Hasan,Monira Sarmin,Subhasish Das,Ishita Mostafa,Shahana Parveen,Mustafizur Rahman,Shams El Arifeen,John D. Clemens,Tahmeed Ahmed +11 more
TL;DR: In this paper , a multivariable logistic regression was done to identify the factors associated with COVID-19 positivity among staff and their family members of icddr,b, a health research institute located in Bangladesh.
Management of novel coronavirus infection in ICU/ 重症监护病房应对新型冠状病毒感染的管理对策
TL;DR: Detailed response management strategies, including the establishment of core groups, standardization of diagnosis and treatment process, strengthening personnel management, multimodal training assessment, and overall allocation of protection materials are formulated.
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A qualitative analysis of perspectives of district level frontline managers in Karnataka during first wave of COVID 19
Sunhitha Velamala,N R Ramesh Masthi,Mohammad Waseem Ansari,Rashmi Kundapur,Sumit Aggarwal,Huluvadi Shivalingaiah Anwith,Anusha Rashmi +6 more
TL;DR: In this article , the authors tried to understand these factors from a local perspective that will help in better planning and management of situation for the future, by taking in depth interviews of frontline managers regarding the management of COVID 19 pandemic situation.
References
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Fast and accurate short read alignment with Burrows–Wheeler transform
Heng Li,Richard Durbin +1 more
TL;DR: Burrows-Wheeler Alignment tool (BWA) is implemented, a new read alignment package that is based on backward search with Burrows–Wheeler Transform (BWT), to efficiently align short sequencing reads against a large reference sequence such as the human genome, allowing mismatches and gaps.
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Trimmomatic: a flexible trimmer for Illumina sequence data
TL;DR: Timmomatic is developed as a more flexible and efficient preprocessing tool, which could correctly handle paired-end data and is shown to produce output that is at least competitive with, and in many cases superior to, that produced by other tools, in all scenarios tested.
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Isolation of a Novel Coronavirus from a Man with Pneumonia in Saudi Arabia
Ali Moh Zaki,Sander van Boheemen,Theo M. Bestebroer,Albert D. M. E. Osterhaus,Ron A. M. Fouchier +4 more
TL;DR: The clinical picture was remarkably similar to that of the severe acute respiratory syndrome (SARS) outbreak in 2003 and reminds us that animal coronaviruses can cause severe disease in humans.
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Origin and evolution of pathogenic coronaviruses
Jie Cui,Fang Li,Zhengli Shi +2 more
TL;DR: The viral factors that enabled the emergence of diseases such as severe acute respiratory syndrome and Middle East respiratory syndrome are explored and the diversity and potential of bat-borne coronaviruses are highlighted.
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SARS and MERS: recent insights into emerging coronaviruses
TL;DR: The emergence of Middle East respiratory syndrome coronavirus (MERS-CoV) in 2012 marked the second introduction of a highly pathogenic coronav virus into the human population in the twenty-first century, and the current state of development of measures to combat emerging coronaviruses is discussed.
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