Identification of a novel coronavirus causing severe pneumonia in human: a descriptive study.
Lili Ren,Ye Ming Wang,Zhiqiang Wu,Zi Chun Xiang,Li Guo,Teng Xu,Yong Zhong Jiang,Yan Xiong,Li Yongjun,Xing Wang Li,Hui Li,Guo Hui Fan,Guo Hui Fan,Xiao Ying Gu,Xiao Ying Gu,Yan Xiao,Hong Gao,Jiu Yang Xu,Fan Yang,Xinming Wang,Chao Wu,Lan Chen,Yi Wei Liu,Bo Liu,Jian Yang,Xiao Rui Wang,Jie Dong,Li Li,Chao Lin Huang,Jian Ping Zhao,Yi Hu,Zhen Shun Cheng,Lin Lin Liu,Zhao Hui Qian,Chuan Qin,Qi Jin,Bin Cao,Bin Cao,Jianwei Wang +38 more
TLDR
A novel bat-borne CoV was identified that is associated with severe and fatal respiratory disease in humans and the amino acid sequence of the tentative receptor-binding domain resembles that of SARS-CoV, indicating that these viruses might use the same receptor.Citations
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Comparing the COVID-19 pandemic in space and over time in Europe, using numbers of deaths, crude rates and adjusted mortality trend ratios
Valentina Gallo,Paolo Chiodini,Dario Bruzzese,Elias Kondilis,Daniel Howdon,Jochen O. Mierau,Raj Bhopal +6 more
TL;DR: The authors urge the WHO, given the absence of age and sex-specific mortality data for direct standardisation, to adopt this method to estimate the comparative mortality from COVID19 pandemic worldwide.
Journal ArticleDOI
A COVID-19 case report from asymptomatic contact: implication for contact isolation and incubation management.
Zhu Changqiang,Shi-Ding Gao,Yan Xu,Xiao-Hong Yang,Fuqiang Ye,Ai Lele,Rui-Chen Lv,Bin Zhang,Yin Li,Heng Lv,Yun-Sheng Liu,Chun-Meng Shi,Chunhui Wang,Tan Weilong +13 more
TL;DR: It is suggested that, in the early phase of COVID-19 pneumonia, routine screening could miss patients who were virus carriers and highlight travel history is of paramount importance for the early detection and isolation of severe acute respiratory syndrome coronavirus 2 cases.
Journal ArticleDOI
Clinical characteristics of 41 patients with pneumonia due to 2019 novel coronavirus disease (COVID-19) in Jilin, China.
TL;DR: Significant differences among the groups suggest that several clinical parameters may serve as biomarkers of COVID-19 severity at hospital admission, and Elevated cTnI could be considered as a predictor of severe COvid-19, reflecting the prognosis of patients with severe CO VID-19.
Journal ArticleDOI
An overview of SARS-CoV-2 (COVID-19) infection and the importance of molecular hydrogen as an adjunctive therapy
TL;DR: The aim is to review the current research into Sars-CoV-2 and to better understand how treatment with molecular hydrogen is likely to affect cellular responses during SARS-Cov-2 infection.
Journal ArticleDOI
A performance evaluation and inter-laboratory comparison of community face coverings media in the context of covid-19 pandemic
Soleiman Bourrous,Mathieu Barrault,Victor Mocho,Stéphane Poirier,Nathalie Bardin-Monnier,Augustin Charvet,Dominique Thomas,A. Bescond,Axel Fouqueau,Tatiana Mace,François Gaie-Levrel,François-Xavier Ouf +11 more
TL;DR: In this paper, an analysis of 233 materials made of woven, non-woven and mixed fibrous material has been done in terms of filtration efficiency and air permeability.
References
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Fast and accurate short read alignment with Burrows–Wheeler transform
Heng Li,Richard Durbin +1 more
TL;DR: Burrows-Wheeler Alignment tool (BWA) is implemented, a new read alignment package that is based on backward search with Burrows–Wheeler Transform (BWT), to efficiently align short sequencing reads against a large reference sequence such as the human genome, allowing mismatches and gaps.
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Trimmomatic: a flexible trimmer for Illumina sequence data
TL;DR: Timmomatic is developed as a more flexible and efficient preprocessing tool, which could correctly handle paired-end data and is shown to produce output that is at least competitive with, and in many cases superior to, that produced by other tools, in all scenarios tested.
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Isolation of a Novel Coronavirus from a Man with Pneumonia in Saudi Arabia
Ali Moh Zaki,Sander van Boheemen,Theo M. Bestebroer,Albert D. M. E. Osterhaus,Ron A. M. Fouchier +4 more
TL;DR: The clinical picture was remarkably similar to that of the severe acute respiratory syndrome (SARS) outbreak in 2003 and reminds us that animal coronaviruses can cause severe disease in humans.
Journal ArticleDOI
Origin and evolution of pathogenic coronaviruses
Jie Cui,Fang Li,Zhengli Shi +2 more
TL;DR: The viral factors that enabled the emergence of diseases such as severe acute respiratory syndrome and Middle East respiratory syndrome are explored and the diversity and potential of bat-borne coronaviruses are highlighted.
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SARS and MERS: recent insights into emerging coronaviruses
TL;DR: The emergence of Middle East respiratory syndrome coronavirus (MERS-CoV) in 2012 marked the second introduction of a highly pathogenic coronav virus into the human population in the twenty-first century, and the current state of development of measures to combat emerging coronaviruses is discussed.
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