Identification of a novel coronavirus causing severe pneumonia in human: a descriptive study.
Lili Ren,Ye Ming Wang,Zhiqiang Wu,Zi Chun Xiang,Li Guo,Teng Xu,Yong Zhong Jiang,Yan Xiong,Li Yongjun,Xing Wang Li,Hui Li,Guo Hui Fan,Guo Hui Fan,Xiao Ying Gu,Xiao Ying Gu,Yan Xiao,Hong Gao,Jiu Yang Xu,Fan Yang,Xinming Wang,Chao Wu,Lan Chen,Yi Wei Liu,Bo Liu,Jian Yang,Xiao Rui Wang,Jie Dong,Li Li,Chao Lin Huang,Jian Ping Zhao,Yi Hu,Zhen Shun Cheng,Lin Lin Liu,Zhao Hui Qian,Chuan Qin,Qi Jin,Bin Cao,Bin Cao,Jianwei Wang +38 more
TLDR
A novel bat-borne CoV was identified that is associated with severe and fatal respiratory disease in humans and the amino acid sequence of the tentative receptor-binding domain resembles that of SARS-CoV, indicating that these viruses might use the same receptor.Citations
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Perceived barriers in online learning among nursing students during the COVID-19 pandemic in Indonesia
Bayu Fandhi Achmad,Akbar Satria Fitriawan,Dedi Kurniawan,Raisa Farida Kafil,Listyana Natalia Retnaningsih,Wiwit Ananda Wahyu Setyaningsih +5 more
TL;DR: In this paper, the authors used a cross-sectional design and involved 530 undergraduate nursing students from five universities in Indonesia participated in this study, and the questionnaire consisted of four sections to obtain the following data: socodemographic characteristic, information about online learning, platform used for online learning and perceived barriers in online learning.
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Covid-19 pandemic outburst in Saudi Arabia: A glimpse.
TL;DR: This short review report very briefly highlights covid-19 syndromes; propagation; Middle East outburst, natural products as cure for viral diseases, probable psychosomatic effects, protective measures and Islamic wisdom.
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Evolution, Interspecies Transmission, and Zoonotic Significance of Animal Coronaviruses.
Prapti Parkhe,Subhash Verma +1 more
TL;DR: In this article, important aspects of coronaviruses infecting livestock, birds, and pets, in particular, their structure and genome organization having a bearing on evolutionary and zoonotic outcomes, have been discussed.
Journal ArticleDOI
Computer Aided COVID-19 Diagnosis in Pandemic Era Using CNN in Chest X-ray Images
Ali Alqahtani,Mirza Mumtaz Zahoor,Rimsha Nasrullah,Aqil Fareed,Ahmad Afzaal Cheema,Abdullah Shahrose,Muhammad Irfan,Abdulmajeed Alqhatani,Abdulaziz A. Alsulami,Maryam Zaffar,Saifur Rahman +10 more
TL;DR: This work developed a novel computationally light and optimized deep Convolutional Neural Networks (CNNs) based framework for chest X-ray analysis and proposed a new COV-Net to learn COVID-specific patterns fromchest X-rays and employed several machine learning classifiers to enhance the discrimination power of the presented framework.
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A brief molecular insight of COVID-19: epidemiology, clinical manifestation, molecular mechanism, cellular tropism and immuno-pathogenesis.
Sweta Singh,Rakesh Pandey,Sarika Tomar,Raunak Varshney,Darshika Sharma,Gurudutta Gangenahalli +5 more
TL;DR: In this paper, the authors summarized the overall picture of SARS-CoV-2 including origin/ emergence, epidemiology, pathogenesis, genome organization, comparative analysis with other CoVs, infection and replication mechanism along with cellular tropism and immunopathogenesis which will provide a brief panoramic view about the virus and disease.
References
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Fast and accurate short read alignment with Burrows–Wheeler transform
Heng Li,Richard Durbin +1 more
TL;DR: Burrows-Wheeler Alignment tool (BWA) is implemented, a new read alignment package that is based on backward search with Burrows–Wheeler Transform (BWT), to efficiently align short sequencing reads against a large reference sequence such as the human genome, allowing mismatches and gaps.
Journal ArticleDOI
Trimmomatic: a flexible trimmer for Illumina sequence data
TL;DR: Timmomatic is developed as a more flexible and efficient preprocessing tool, which could correctly handle paired-end data and is shown to produce output that is at least competitive with, and in many cases superior to, that produced by other tools, in all scenarios tested.
Journal ArticleDOI
Isolation of a Novel Coronavirus from a Man with Pneumonia in Saudi Arabia
Ali Moh Zaki,Sander van Boheemen,Theo M. Bestebroer,Albert D. M. E. Osterhaus,Ron A. M. Fouchier +4 more
TL;DR: The clinical picture was remarkably similar to that of the severe acute respiratory syndrome (SARS) outbreak in 2003 and reminds us that animal coronaviruses can cause severe disease in humans.
Journal ArticleDOI
Origin and evolution of pathogenic coronaviruses
Jie Cui,Fang Li,Zhengli Shi +2 more
TL;DR: The viral factors that enabled the emergence of diseases such as severe acute respiratory syndrome and Middle East respiratory syndrome are explored and the diversity and potential of bat-borne coronaviruses are highlighted.
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SARS and MERS: recent insights into emerging coronaviruses
TL;DR: The emergence of Middle East respiratory syndrome coronavirus (MERS-CoV) in 2012 marked the second introduction of a highly pathogenic coronav virus into the human population in the twenty-first century, and the current state of development of measures to combat emerging coronaviruses is discussed.
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