Identification of a novel coronavirus causing severe pneumonia in human: a descriptive study.
Lili Ren,Ye Ming Wang,Zhiqiang Wu,Zi Chun Xiang,Li Guo,Teng Xu,Yong Zhong Jiang,Yan Xiong,Li Yongjun,Xing Wang Li,Hui Li,Guo Hui Fan,Guo Hui Fan,Xiao Ying Gu,Xiao Ying Gu,Yan Xiao,Hong Gao,Jiu Yang Xu,Fan Yang,Xinming Wang,Chao Wu,Lan Chen,Yi Wei Liu,Bo Liu,Jian Yang,Xiao Rui Wang,Jie Dong,Li Li,Chao Lin Huang,Jian Ping Zhao,Yi Hu,Zhen Shun Cheng,Lin Lin Liu,Zhao Hui Qian,Chuan Qin,Qi Jin,Bin Cao,Bin Cao,Jianwei Wang +38 more
TLDR
A novel bat-borne CoV was identified that is associated with severe and fatal respiratory disease in humans and the amino acid sequence of the tentative receptor-binding domain resembles that of SARS-CoV, indicating that these viruses might use the same receptor.Citations
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Designing of thiazolidinones against chicken pox, monkey pox, and hepatitis viruses: A computational approach
TL;DR: In this paper , four different series (D-G) of thiazolidinone were designed starting from different amines which were further condensed with various aldehydes, and the different electrochemical parameters of the compounds are predicted using quantum mechanical modeling approach with Gaussian.
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Management of novel coronavirus infection in ICU
TL;DR: In this article, the authors have formulated detailed response management strategies, including the establishment of core groups, standardization of diagnosis and treatment process, strengthening personnel management, multimodal training assessment, and overall allocation of protection materials.
Posted ContentDOI
Biostatistical Investigation of Correlation Between COVID-19 and Diabetes Mellitus
Zahra Eynizadeh,Zahra Ameli,Mahdieh Sahranavard,Mobina Daneshparvar,Mobina Abdollahi Dolagh,Mahboobeh Roozkhosh,Mohammad Reza Ejtehadi,Maryam Azimzadeh Irani +7 more
TL;DR: By increasing the prevalence of Diabetes Mellitus, the prevalenceof COVID-19 cases may also increase and the results show an increasing pattern of the correlation coefficient in the last three windows.
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The effects of primary care monitoring strategies on COVID-19 related hospitalisation and mortality: a retrospective electronic medical records review in a northern Italian province, the MAGMA study
Alice Serafini,L Palandri,Peter Konstantin Kurotschka,C. Giansante,Maria Rita Sabattini,Marina Scarpa,Davide Fornaciari,Francesco Bellelli,Maria Stella Padula,Elena Righi,Silvia Riccomi +10 more
TL;DR: In this paper , a retrospective observational study of SARS-CoV-2 infected adult outpatients managed by GPs in Modena (Italy) from March 2020 to April 2021 was conducted.
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COVID-19 in Italy: Remedies to Reduce the Infections and Deaths
TL;DR: In this article, the authors discuss the aspects of infection and deaths due to COVID-19 in Italy and the Lombardy Region is the most infected region in the country, and the disease spreads in Italy very fast and the north of the country is mostly affected.
References
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Fast and accurate short read alignment with Burrows–Wheeler transform
Heng Li,Richard Durbin +1 more
TL;DR: Burrows-Wheeler Alignment tool (BWA) is implemented, a new read alignment package that is based on backward search with Burrows–Wheeler Transform (BWT), to efficiently align short sequencing reads against a large reference sequence such as the human genome, allowing mismatches and gaps.
Journal ArticleDOI
Trimmomatic: a flexible trimmer for Illumina sequence data
TL;DR: Timmomatic is developed as a more flexible and efficient preprocessing tool, which could correctly handle paired-end data and is shown to produce output that is at least competitive with, and in many cases superior to, that produced by other tools, in all scenarios tested.
Journal ArticleDOI
Isolation of a Novel Coronavirus from a Man with Pneumonia in Saudi Arabia
Ali Moh Zaki,Sander van Boheemen,Theo M. Bestebroer,Albert D. M. E. Osterhaus,Ron A. M. Fouchier +4 more
TL;DR: The clinical picture was remarkably similar to that of the severe acute respiratory syndrome (SARS) outbreak in 2003 and reminds us that animal coronaviruses can cause severe disease in humans.
Journal ArticleDOI
Origin and evolution of pathogenic coronaviruses
Jie Cui,Fang Li,Zhengli Shi +2 more
TL;DR: The viral factors that enabled the emergence of diseases such as severe acute respiratory syndrome and Middle East respiratory syndrome are explored and the diversity and potential of bat-borne coronaviruses are highlighted.
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SARS and MERS: recent insights into emerging coronaviruses
TL;DR: The emergence of Middle East respiratory syndrome coronavirus (MERS-CoV) in 2012 marked the second introduction of a highly pathogenic coronav virus into the human population in the twenty-first century, and the current state of development of measures to combat emerging coronaviruses is discussed.
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