Identification of a novel coronavirus causing severe pneumonia in human: a descriptive study.
Lili Ren,Ye Ming Wang,Zhiqiang Wu,Zi Chun Xiang,Li Guo,Teng Xu,Yong Zhong Jiang,Yan Xiong,Li Yongjun,Xing Wang Li,Hui Li,Guo Hui Fan,Guo Hui Fan,Xiao Ying Gu,Xiao Ying Gu,Yan Xiao,Hong Gao,Jiu Yang Xu,Fan Yang,Xinming Wang,Chao Wu,Lan Chen,Yi Wei Liu,Bo Liu,Jian Yang,Xiao Rui Wang,Jie Dong,Li Li,Chao Lin Huang,Jian Ping Zhao,Yi Hu,Zhen Shun Cheng,Lin Lin Liu,Zhao Hui Qian,Chuan Qin,Qi Jin,Bin Cao,Bin Cao,Jianwei Wang +38 more
TLDR
A novel bat-borne CoV was identified that is associated with severe and fatal respiratory disease in humans and the amino acid sequence of the tentative receptor-binding domain resembles that of SARS-CoV, indicating that these viruses might use the same receptor.Citations
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La vacuna frente a la COVID-19 y la confianza institucional
TL;DR: In this paper, a modelo etico of primera persona, basado en la responsabilidad, is presented, in order to pass from una etica normativa to a etica de comportamiento responsable.
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Multicenter assessment of shotgun metagenomics for pathogen detection
Donglai Liu,Haiwei Zhou,Teng Xu,Qiwen Yang,Xi Mo,Dawei Shi,Jing-Wen Ai,Jingjia Zhang,Yue Tao,Donghua Wen,Yigang Tong,Lili Ren,Wen Zhang,Shumei Xie,Weijun Chen,Wanli Xing,Jinyin Zhao,Yilan Wu,Xianfa Meng,Chuan Ouyang,Zhi Jiang,Zhikun Liang,Haiqin Tan,Yuan Fang,Nan Qin,Yuanlin Guan,Wei Gai,Sihong Xu,Wenjuan Wu,Wenhong Zhang,Chuntao Zhang,Youchun Wang +31 more
TL;DR: In this paper, a reference panel and performance metrics were designed and used to examine the performance of shotgun metagenomics at 17 laboratories in a coordinated collaborative study, comprehensively assessed the reliability, key performance determinants, reproducibility, and quantitative potential.
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Point of Care Diagnostic Devices for Rapid Detection of Novel Coronavirus (SARS-nCoV19) Pandemic: A Review
TL;DR: In this article, a review of nucleic acid, serological, multiplex, and point-of-care (PoC) devices for detection of SARS-nCoV-2 virus infection in humans is presented.
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Seroprevalence of SARS-CoV-2 IgG Antibodies in Corsica (France), April and June 2020
Lisandru Capai,Nazli Ayhan,Nazli Ayhan,Shirley Masse,Jean Canarelli,Stéphane Priet,Marie-Helene Simeoni,Rémi N. Charrel,Xavier de Lamballerie,Alessandra Falchi +9 more
TL;DR: The present study showed a low seroprevalence for COVID-19 in Corsica, a finding that is in accordance with values reported for other French regions in which the impact of the pandemic was low.
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COVID-19 Diagnosis: A Comprehensive Review of the RT-qPCR Method for Detection of SARS-CoV-2
Debashis Dutta,Sarah Naiyer,Sabanaz Mansuri,Neeraj Soni,Vandana Singh,Khalid Hussain Bhat,Nishant Singh,Gunjan Arora,M. Shahid Mansuri +8 more
TL;DR: A comprehensive review of the natural history, pathology, molecular biology, and efficient diagnostic methods of COVID-19, detecting SARS-CoV-2 in collected samples and reviewing the gold standard RT-qPCR method to confer a better understanding and application to combat the CO VID-19 pandemic.
References
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Fast and accurate short read alignment with Burrows–Wheeler transform
Heng Li,Richard Durbin +1 more
TL;DR: Burrows-Wheeler Alignment tool (BWA) is implemented, a new read alignment package that is based on backward search with Burrows–Wheeler Transform (BWT), to efficiently align short sequencing reads against a large reference sequence such as the human genome, allowing mismatches and gaps.
Journal ArticleDOI
Trimmomatic: a flexible trimmer for Illumina sequence data
TL;DR: Timmomatic is developed as a more flexible and efficient preprocessing tool, which could correctly handle paired-end data and is shown to produce output that is at least competitive with, and in many cases superior to, that produced by other tools, in all scenarios tested.
Journal ArticleDOI
Isolation of a Novel Coronavirus from a Man with Pneumonia in Saudi Arabia
Ali Moh Zaki,Sander van Boheemen,Theo M. Bestebroer,Albert D. M. E. Osterhaus,Ron A. M. Fouchier +4 more
TL;DR: The clinical picture was remarkably similar to that of the severe acute respiratory syndrome (SARS) outbreak in 2003 and reminds us that animal coronaviruses can cause severe disease in humans.
Journal ArticleDOI
Origin and evolution of pathogenic coronaviruses
Jie Cui,Fang Li,Zhengli Shi +2 more
TL;DR: The viral factors that enabled the emergence of diseases such as severe acute respiratory syndrome and Middle East respiratory syndrome are explored and the diversity and potential of bat-borne coronaviruses are highlighted.
Journal ArticleDOI
SARS and MERS: recent insights into emerging coronaviruses
TL;DR: The emergence of Middle East respiratory syndrome coronavirus (MERS-CoV) in 2012 marked the second introduction of a highly pathogenic coronav virus into the human population in the twenty-first century, and the current state of development of measures to combat emerging coronaviruses is discussed.
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