Laser speckle contrast imaging in biomedical optics
David A. Boas,Andrew K. Dunn +1 more
Reads0
Chats0
TLDR
The underlying physics of speckle contrast imaging is reviewed, recent developments to improve the quantitative accuracy of blood flow measures are discussed and applications in neuroscience, dermatology and ophthalmology are reviewed.Abstract:
First introduced in the 1980s, laser speckle contrast imaging is a powerful tool for full-field imaging of blood flow. Recently laser speckle contrast imaging has gained increased attention, in part due to its rapid adoption for blood flow studies in the brain. We review the underlying physics of speckle contrast imaging and discuss recent developments to improve the quantitative accuracy of blood flow measures. We also review applications of laser speckle contrast imaging in neuroscience, dermatology and ophthalmology.read more
Citations
More filters
Proceedings ArticleDOI
Establishing diffuse speckle contrast signal relationship with blood flow
TL;DR: In this article, the reduction in speckle contrast due to shear-induced motions is studied by theory and Monte Carlo simulations, and the quantitative relationship between speckles contrast and absolute blood flow in a realistic vascular network is established.
Proceedings ArticleDOI
Adjustment of the cerebral and peripheral blood flow dynamics at the pre-stroke stage
Olga N. Pavlova,Arkady S. Abdurashitov,Yasir K. Mohammad,Oxana Semyachkina-Glushkovskaya,Alexey N. Pavlov +4 more
TL;DR: Using the laser speckle contrast imaging and the wavelet-based multifractal analysis, the adjustment of the numerical measures characterizing the blood flow dynamics at the pre-stroke stage is revealed and a hypothesis about a pathological synchronization is suggested.
Journal ArticleDOI
Imaging sensor research for viscoelastic detection of composite resin
Cheng-Feng Xie,Xiaojun Xu,Nenghao Xia,YanSong Liu,Youjiang Zhao,Jiulin Shi,Mengyu Wang,Xingdao He +7 more
TL;DR: The results showed that the composite resin cured ideally in the ninth second and exhibited a high linear correlation (r =0.965, p = 0.007 81).
Proceedings ArticleDOI
Quadratic Discriminant Analysis Performance for Blood Flow Prediction in Speckle Imaging
TL;DR: In this article , Quadratic Discriminant Analysis (QDA) was used to predict flow in speckle contrast imaging. But, the accuracy of 96%, recall of 97.9%, and specificity of 56%, the study demonstrated that quadratic discriminant analysis is the most precise technique that must be considered for flow prediction.
Proceedings ArticleDOI
Quadratic Discriminant Analysis Performance for Blood Flow Prediction in Speckle Imaging
TL;DR: In this article , Quadratic Discriminant Analysis (QDA) was used to predict flow in speckle contrast imaging. But, the accuracy of 96%, recall of 97.9%, and specificity of 56%, the study demonstrated that quadratic discriminant analysis is the most precise technique that must be considered for flow prediction.
References
More filters
Journal ArticleDOI
Pathobiology of ischaemic stroke: an integrated view
TL;DR: This article provides a framework that can be used to generate testable hypotheses and treatment strategies that are linked to the appearance of specific pathophysiological events within the ischaemic brain.
Journal ArticleDOI
Spreading depression of activity in the cerebral cortex
TL;DR: In this article, an interesting response elicited by electrical stimulation was noticed in the cortex of rabbits, and the distinctive feature of this response was a marked, enduring reduction of the "spontaneous" electrical activity of the cortex.
ReportDOI
Statistical properties of laser sparkle patterns
TL;DR: In this article, the first order statistics of the observed electric-field strength, the observed light intensity, and observed light phase are examined, and the autocorrelation functions of the complex field and intensity processes are investigated, and that of the electric field is found to be proportional to the Fourier transform of the light intensity distribution incident on the scattering surface.
Related Papers (5)
Laser speckle contrast analysis (LASCA): a nonscanning, full-field technique for monitoring capillary blood flow
J. D. Briers,Sian Webster +1 more