Laser speckle contrast imaging in biomedical optics
David A. Boas,Andrew K. Dunn +1 more
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TLDR
The underlying physics of speckle contrast imaging is reviewed, recent developments to improve the quantitative accuracy of blood flow measures are discussed and applications in neuroscience, dermatology and ophthalmology are reviewed.Abstract:
First introduced in the 1980s, laser speckle contrast imaging is a powerful tool for full-field imaging of blood flow. Recently laser speckle contrast imaging has gained increased attention, in part due to its rapid adoption for blood flow studies in the brain. We review the underlying physics of speckle contrast imaging and discuss recent developments to improve the quantitative accuracy of blood flow measures. We also review applications of laser speckle contrast imaging in neuroscience, dermatology and ophthalmology.read more
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Journal ArticleDOI
High speed determination of laser wavelength using Poincaré descriptors of speckle
TL;DR: In this paper, an arithmetically simple method to measure wavelength changes with dynamic speckle was proposed, based on a Poincare descriptor of the speckles pattern.
Journal ArticleDOI
Monitoring microvascular perfusion variations with laser speckle contrast imaging using a view-based temporal template method.
TL;DR: This work proposes here to analyze if a view-based temporal template method, the motion history image (MHI) algorithm, may be of use in detecting the perfusion variations locations, and shows that MHI identifies the area in which perfusion evolves with time.
Journal ArticleDOI
Effect of static scatterers in laser speckle contrast imaging: an experimental study on correlation and contrast
TL;DR: It was found that the laser speckle correlation could be used to estimate the relative concentration of static/dynamic scatterers within a sample and proved to be independent of the dynamic scatterer velocity, which is a fundamental characteristic to be used in contrast correction.
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Yu-Chang Yeh,Wen-Je Ko,Kuang-Cheng Chan,Shou-Zen Fan,Jui-Chang Tsai,Ya-Jung Cheng,Wei-Zen Sun +6 more
TL;DR: The results revealed that eritoran restored the mean arterial pressure and attenuated endotoxin-induced elevation in the serum level of D-dimer, indicating that Eritoran can reduce microcirculatory dysfunction in endotoxemic rats.
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