Laser speckle contrast imaging in biomedical optics
David A. Boas,Andrew K. Dunn +1 more
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TLDR
The underlying physics of speckle contrast imaging is reviewed, recent developments to improve the quantitative accuracy of blood flow measures are discussed and applications in neuroscience, dermatology and ophthalmology are reviewed.Abstract:
First introduced in the 1980s, laser speckle contrast imaging is a powerful tool for full-field imaging of blood flow. Recently laser speckle contrast imaging has gained increased attention, in part due to its rapid adoption for blood flow studies in the brain. We review the underlying physics of speckle contrast imaging and discuss recent developments to improve the quantitative accuracy of blood flow measures. We also review applications of laser speckle contrast imaging in neuroscience, dermatology and ophthalmology.read more
Citations
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Enhanced multiresolution wavelet analysis of cerebrovascular dynamics
Alexey N. Pavlov,Olga N. Pavlova +1 more
TL;DR: It is shown that the use of simple statistical measures limits the information that can be extracted during data processing and taking into account the correlation features in addition to the width of the probability density is a possible way to improve the characterization of the effects produced by “jumps” in blood pressure.
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BioShuttle Mobility in Living Cells Studied with High-Resolution FCS & CLSM Methodologies
Klaus Braun,Marcel Beining,Manfred Wiessler,Twan Lammers,Rüdiger Pipkorn,Ute Hennrich,Kiyoshi Nokihara,Wolfhard Semmler,Jürgen Debus,Waldemar Waldeck +9 more
TL;DR: The transport properties of the peptide-based BioShuttle transporter are characterized using FFM and CLSM methods and results in a multi-faceted field of applications, also as a theranostic tool.
Posted ContentDOI
Dynamic Laser Speckle Imaging
Dmitry D. Postnov,Dmitry D. Postnov,Jianbo Tang,Sefik Evren Erdener,Kıvılcım Kılıç,David A. Boas +5 more
TL;DR: DLSI is applied to image cerebral blood flow in mouse through a cranial window and it is shown that the generally accepted form of g1(τ), is applicable only to visible surface vessels of a specific size (20 – 200μm).
Dissertation
Experimental study of speckle generated by semiconductor light sources: application in double pass imaging
TL;DR: In this paper, the authors compared an LD, a light-emitting diode and a superluminescent diode in terms of speckle formation, cost and usability in double pass imaging systems.
References
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Journal ArticleDOI
Pathobiology of ischaemic stroke: an integrated view
TL;DR: This article provides a framework that can be used to generate testable hypotheses and treatment strategies that are linked to the appearance of specific pathophysiological events within the ischaemic brain.
Journal ArticleDOI
Spreading depression of activity in the cerebral cortex
TL;DR: In this article, an interesting response elicited by electrical stimulation was noticed in the cortex of rabbits, and the distinctive feature of this response was a marked, enduring reduction of the "spontaneous" electrical activity of the cortex.
ReportDOI
Statistical properties of laser sparkle patterns
TL;DR: In this article, the first order statistics of the observed electric-field strength, the observed light intensity, and observed light phase are examined, and the autocorrelation functions of the complex field and intensity processes are investigated, and that of the electric field is found to be proportional to the Fourier transform of the light intensity distribution incident on the scattering surface.
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