Laser speckle contrast imaging in biomedical optics
David A. Boas,Andrew K. Dunn +1 more
Reads0
Chats0
TLDR
The underlying physics of speckle contrast imaging is reviewed, recent developments to improve the quantitative accuracy of blood flow measures are discussed and applications in neuroscience, dermatology and ophthalmology are reviewed.Abstract:
First introduced in the 1980s, laser speckle contrast imaging is a powerful tool for full-field imaging of blood flow. Recently laser speckle contrast imaging has gained increased attention, in part due to its rapid adoption for blood flow studies in the brain. We review the underlying physics of speckle contrast imaging and discuss recent developments to improve the quantitative accuracy of blood flow measures. We also review applications of laser speckle contrast imaging in neuroscience, dermatology and ophthalmology.read more
Citations
More filters
Journal ArticleDOI
Design and characterization of a microfabricated hydrogen clearance blood flow sensor.
TL;DR: Microfabrication allows for the high-throughput production of reproducible devices that are capable of monitoring deep brain CBF with sub-minute resolution, and can resolve physiological changes occurring on a shorter timescale than existing gas clearance measurements.
Journal ArticleDOI
Evaluation of biological speckle activity: Using variational mode decomposition
TL;DR: In this paper, the authors investigated the application of the variational mode decomposition (VM decomposition) in dynamic speckle sequences, which can obtain more selective information about the characteristics of speckles and isolate undesired covariates.
Journal ArticleDOI
Quasiresonant diffusion of wave packets in one-dimensional disordered mosaic lattices
TL;DR: In this paper , the authors investigated the time evolution of wave packets incident on one-dimensional semi-infinite lattices with mosaic modulated random on-site potentials, which are characterized by the integer-valued modulation period κ and the disorder strength W .
Proceedings ArticleDOI
Noninvasive Noncontact 3D Optical Imaging of Blood Flow Distributions in Animals and Humans
Siavash Mazdeyasna,Chong Huang,Mingjun Zhao,Alisha R. Bonaroti,Kathryn E. Saatman,Lei Chen,Elie G. Abu Jawdeh,Henrietta S. Bada,Brandon A. Miller,Lesley Wong,Guoqiang Yu +10 more
TL;DR: The modified and adapted scDCT system with flexible ROIs and imaging depths has the potential to be used in many preclinical and clinical settings for noninvasive assessment of tissue hemodynamics and viability.
Journal ArticleDOI
Scattering spot imaging for the determination of optical and dynamical properties of viscoelastic media
TL;DR: In this article, a simple scheme for the assessment of optical as well as dynamical properties of viscoelastic media is presented, for the first time, using scattering spot imaging with a standard CCD camera at multiple exposure times and with a monochromatic continuous wave illuminance.
References
More filters
Journal ArticleDOI
Pathobiology of ischaemic stroke: an integrated view
TL;DR: This article provides a framework that can be used to generate testable hypotheses and treatment strategies that are linked to the appearance of specific pathophysiological events within the ischaemic brain.
Journal ArticleDOI
Spreading depression of activity in the cerebral cortex
TL;DR: In this article, an interesting response elicited by electrical stimulation was noticed in the cortex of rabbits, and the distinctive feature of this response was a marked, enduring reduction of the "spontaneous" electrical activity of the cortex.
ReportDOI
Statistical properties of laser sparkle patterns
TL;DR: In this article, the first order statistics of the observed electric-field strength, the observed light intensity, and observed light phase are examined, and the autocorrelation functions of the complex field and intensity processes are investigated, and that of the electric field is found to be proportional to the Fourier transform of the light intensity distribution incident on the scattering surface.
Related Papers (5)
Laser speckle contrast analysis (LASCA): a nonscanning, full-field technique for monitoring capillary blood flow
J. D. Briers,Sian Webster +1 more