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Laser speckle contrast imaging in biomedical optics

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TLDR
The underlying physics of speckle contrast imaging is reviewed, recent developments to improve the quantitative accuracy of blood flow measures are discussed and applications in neuroscience, dermatology and ophthalmology are reviewed.
Abstract
First introduced in the 1980s, laser speckle contrast imaging is a powerful tool for full-field imaging of blood flow. Recently laser speckle contrast imaging has gained increased attention, in part due to its rapid adoption for blood flow studies in the brain. We review the underlying physics of speckle contrast imaging and discuss recent developments to improve the quantitative accuracy of blood flow measures. We also review applications of laser speckle contrast imaging in neuroscience, dermatology and ophthalmology.

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3D structural vibration identification from dynamic point clouds

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Neurophotonic Tools for Microscopic Measurements and Manipulation: Status Report

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Fabrication of various optical tissue phantoms by the spin-coating method

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Shannon entropy and degree of polarization of a speckle pattern.

TL;DR: A linear relation between the SE and the standard deviation of intensity of a speckle pattern is established and a change of the SE indicates a change in the randomness of the intensity distribution.
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Multifractal characterization of cerebrovascular dynamics in newborn rats

TL;DR: It is demonstrated that the singularity spectrum estimated with the wavelet-transform modulus maxima (WTMM) technique allows clear characterization of a reduced complexity of blood flow dynamics and changes of the correlation properties at the transformation of normal physiological processes into pathological dynamics that are essentially different at the level of large and small blood vessels.
References
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BookDOI

Dynamic Light Scattering

Robert Pecora
Journal ArticleDOI

Pathobiology of ischaemic stroke: an integrated view

TL;DR: This article provides a framework that can be used to generate testable hypotheses and treatment strategies that are linked to the appearance of specific pathophysiological events within the ischaemic brain.
Book

Statistical Optics

Journal ArticleDOI

Spreading depression of activity in the cerebral cortex

TL;DR: In this article, an interesting response elicited by electrical stimulation was noticed in the cortex of rabbits, and the distinctive feature of this response was a marked, enduring reduction of the "spontaneous" electrical activity of the cortex.
ReportDOI

Statistical properties of laser sparkle patterns

TL;DR: In this article, the first order statistics of the observed electric-field strength, the observed light intensity, and observed light phase are examined, and the autocorrelation functions of the complex field and intensity processes are investigated, and that of the electric field is found to be proportional to the Fourier transform of the light intensity distribution incident on the scattering surface.
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