Journal ArticleDOI
Rate of release of medicaments from ointment bases containing drugs in suspension
TLDR
An equation relating the rate of release of solid drugs suspended in ointment bases into perfect sinks is derived and the final expression is found to be surprisingly simple and convenient.About:
This article is published in Journal of Pharmaceutical Sciences.The article was published on 1961-10-01. It has received 2031 citations till now. The article focuses on the topics: Ointment Bases.read more
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Development and characterization of micellar systems for application as insect repellents.
Thaís Nogueira Barradas,Léa Lopes,Eduardo Ricci-Júnior,Kattya Gyselle de Holanda e Silva,Claudia R. E. Mansur +4 more
TL;DR: Tests suggest that the tested samples exhibit safety profile greater than some commercially available products, and the anisotropic structure may constitute a barrier to diffusion and thereby controlling the drug release effectively.
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Low-Molecular-Weight Gelators as Base Materials for Ointments
TL;DR: In this review, several series of studies related to the creation of ointment base materials with enhanced properties using existing and newly-created LMWGs are summarized.
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Floating-mucoadhesive beads of clarithromycin for the treatment of Helicobacter pylori infection.
TL;DR: Alginate-HPMC beads may be suitable floating-muco-adhesive drug delivery system for delivering clarithromycin to treat stomach ulcers.
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Smart pH/magnetic sensitive Hericium erinaceus residue carboxymethyl chitin/Fe3O4 nanocomposite hydrogels with adjustable characteristics.
Jing Liao,Huihua Huang +1 more
TL;DR: A smart hydrogels with pH/magnetic dual sensitivity was synthesized by in-situ synthesis of Fe3O4 inside carboxymethyl chitin hydrogel matrix prepared from Hericium erinaceus residue and the results showed that Fe3 O4 nanoparticles were successfully synthesized and uniformly distributed within the Hydrogels.
Journal ArticleDOI
Influence of technological factors on formulation of sustained release tablets
TL;DR: In this article, theoretically expected rates of release of solid drugs incorporated into solid matrices have been derived for several model systems, where the drug particles are dispersed in a homogeneous, uniform matrix which acts as the diffusional medium and the particles are incorporated in an essentially granular matrix and released by the leaching action of the penetrating solvent.