Journal ArticleDOI
Rate of release of medicaments from ointment bases containing drugs in suspension
TLDR
An equation relating the rate of release of solid drugs suspended in ointment bases into perfect sinks is derived and the final expression is found to be surprisingly simple and convenient.About:
This article is published in Journal of Pharmaceutical Sciences.The article was published on 1961-10-01. It has received 2031 citations till now. The article focuses on the topics: Ointment Bases.read more
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Transport studies on macromolecules used as drug carriers
TL;DR: A review of the transport of drug molecules through physiological systems via polymeric materials can be found in this paper, where a brief introduction to the fundamentals and concepts which are frequently used in the drug-delivery area are covered in the following sections.
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In Vitro Release Mechanisms of Doxorubicin From a Clinical Bead Drug-Delivery System.
TL;DR: A combination of miniaturized in vitro methods and theoretical modeling are useful to identify the important parameters and processes for DOX release from a micro gel-based DDS.
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Lyophilized insulin nanoparticles prepared from quaternized N-aryl derivatives of chitosan as a new strategy for oral delivery of insulin: in vitro, ex vivo and in vivo characterizations.
TL;DR: As the result of optimized physico-chemical properties, drug release rate, cytotoxicity profile, ex vivo permeation enhancement and increased in vivo absorption, nanoparticles prepared from N-aryl derivatives of chitosan can be considered as valuable method for the oral delivery of insulin.
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Sustained, Controlled and Stimuli-Responsive Drug Release Systems Based on Nanoporous Anodic Alumina with Layer-by-Layer Polyelectrolyte.
Maria Porta-i-Batalla,Chris Eckstein,Elisabet Xifré-Pérez,Pilar Formentín,Josep Ferré-Borrull,Lluis F. Marsal +5 more
TL;DR: This work has created and analyzed a stimuli-responsive drug delivery system based on layer-by-layer pH-responsive polyelectrolyte and nanoporous anodic alumina and demonstrates that it is possible to control the drug release using a polyelectralyte multilayer coating that will act as a gate.
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Spatiotemporal delivery of bioactive molecules for wound healing using stimuli-responsive biomaterials.
Nuria Oliva,Benjamin D. Almquist +1 more
TL;DR: The diverse approaches taken by the biomaterials community for creating stimuli-responsive materials that are beginning to enable spatiotemporal control over the delivery of therapeutics for applications in tissue engineering and regenerative medicine are reviewed.