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Journal ArticleDOI

Rate of release of medicaments from ointment bases containing drugs in suspension

Takeru Higuchi
- 01 Oct 1961 - 
- Vol. 50, Iss: 10, pp 874-875
TLDR
An equation relating the rate of release of solid drugs suspended in ointment bases into perfect sinks is derived and the final expression is found to be surprisingly simple and convenient.
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This article is published in Journal of Pharmaceutical Sciences.The article was published on 1961-10-01. It has received 2031 citations till now. The article focuses on the topics: Ointment Bases.

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Ordered mesoporous carbons for ibuprofen drug loading and release behavior

TL;DR: In this paper, the effect of the ordered mesoporous carbons structures on IBU drug loading and release was studied for the first time, and the results showed that the loading of IBU had not greatly changed the basic ordered pore structure of the OMCs.
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Direct encapsulation of water-soluble drug into silica microcapsules for sustained release applications

TL;DR: In this article, the authors used a sol-gel process of tetraethoxysilane (TEOS) in W/O emulsion with hydrochloric acid (HCl) aqueous solution containing Tween 80 and drug as well as cyclohexane solution containing Span 80.
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5-Fluorouracil trapping in poly(2-hydroxyethyl methacrylate-co-acrylamide) hydrogels: in vitro drug delivery studies

TL;DR: In this paper, the influence of gel formulation on the diffusion of 5-fluorouracil (5-FU) included in poly(2-hydroxyethyl methacrylate-co-acrylamide) (poly(HEMA)-co-A)) hydrogels is reported.
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Hemicellulose from Plant Biomass in Medical and Pharmaceutical Application: A Critical Review.

TL;DR: The application of nature hemicellulose, its degradation products, its derivatives and hemiceLLulose-based materials in the medical field is introduced and their properties and use effects are discussed in detail.
Journal ArticleDOI

Kinetics of diffusion-mediated drug release enhanced by matrix degradation

TL;DR: In this article, modified diffusion equations with a time-dependent diffusion coefficient were derived to formulate the kinetics of drug release from a quickly degradable matrix and compared the theoretical equations with experimental observation.
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