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Journal ArticleDOI

Rate of release of medicaments from ointment bases containing drugs in suspension

Takeru Higuchi
- 01 Oct 1961 - 
- Vol. 50, Iss: 10, pp 874-875
TLDR
An equation relating the rate of release of solid drugs suspended in ointment bases into perfect sinks is derived and the final expression is found to be surprisingly simple and convenient.
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This article is published in Journal of Pharmaceutical Sciences.The article was published on 1961-10-01. It has received 2031 citations till now. The article focuses on the topics: Ointment Bases.

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Journal ArticleDOI

Evaluation of Release Kinetics and Mechanisms of Curcumin and Curcumin-β-Cyclodextrin Inclusion Complex Incorporated in Electrospun Almond Gum/PVA Nanofibers in Simulated Saliva and Simulated Gastrointestinal Conditions

TL;DR: The controlled release of curcumin in simulated gastrointestinal and simulated saliva conditions showed that the nanofibers containing complex had the higher release in comparison of onlyCurcumin at all time points.
Journal ArticleDOI

Cellulose, chitosan, and keratin composite materials. Controlled drug release.

TL;DR: The results clearly indicate that drug release can be controlled and adjusted at any rate by judiciously selecting the concentration of KER in the composites, and indicates that this novel composite can be used in ways which hitherto were not possible, e.g., as a high-performance bandage to treat chronic and ulcerous wounds.
Journal ArticleDOI

Oil and drug control the release rate from lyotropic liquid crystals.

TL;DR: This work presents a comprehensive study of the dimensional structural control of hydrophilic drug release, including 3-d bicontinuous cubic, 2-d lamellar, 1-d hexagonal and 0-d micellar cubic phases in excess water.
Journal ArticleDOI

Development of sustained release fast-disintegrating tablets using various polymer-coated ion-exchange resin complexes.

TL;DR: Complex formation between drugs and ion-exchange resins was investigated and the effects of coating by various aqueous polymeric dispersions on the complexes were evaluated for developing new sustained-release fast-disintegrating tablets (FDTs).
Book ChapterDOI

Natural Polymers vs Synthetic Polymer

TL;DR: In this chapter, various natural polymers are discussed, their advantages over synthetic polymers and role of naturalpolymers in designing novel drug delivery systems are discussed.
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