Journal ArticleDOI
Rate of release of medicaments from ointment bases containing drugs in suspension
TLDR
An equation relating the rate of release of solid drugs suspended in ointment bases into perfect sinks is derived and the final expression is found to be surprisingly simple and convenient.About:
This article is published in Journal of Pharmaceutical Sciences.The article was published on 1961-10-01. It has received 2031 citations till now. The article focuses on the topics: Ointment Bases.read more
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NIR-sensitive UCNP@mSiO2 nanovehicles for on-demand drug release and photodynamic therapy
TL;DR: A near-infrared (NIR) sensitive nanovehicle to reveal synergistic chemotherapy and photodynamic therapy (PDT) and the enhanced cytotoxicity is derived from the synergistic effect of chemotherapy and PDT that would easily be controlled by the acting strength and time of NIR irradiation.
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Modelling of drug release from pellets coated with an insoluble polymeric membrane
TL;DR: A model to accurately describe drug release kinetics from coated pellets where the membrane does not entirely control the release is proposed and the possibility of ab initio optimization, from easy experiments not including coated pellets: drug release from uncoated matrices and permeation kinetics through free films.
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Cellular automata model for drug release from binary matrix and reservoir polymeric devices
TL;DR: A new and widely applicable cellular automata model for diffusion and erosion processes occurring during drug release from polymeric drug release devices is presented, showing easy adaptability of the model to virtually any release system and geometry.
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The Evaluation of Eudragit Microcapsules Manufactured by Solvent Evaporation Using USP Apparatus 1
TL;DR: The formulations containing drug/polymer ratio 1:4 (w/w) were the most appropriate with respect to encapsulation efficiency, flow properties, surface morphology, and drug release characteristics, in all cases.
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Fe3O4@mSiO2 core-shell nanocomposite capped with disulfide gatekeepers for enzyme-sensitive controlled release of anti-cancer drugs.
TL;DR: Multifunctional nanocarriers based on the magnetic Fe3O4 nanoparticle core and bis-(3-carboxy-4-hydroxy phenyl) disulfide modified mesoporous silica shell could play an important role in the development of intracellular delivery nanodevices for cancer therapy.