Journal ArticleDOI
Rate of release of medicaments from ointment bases containing drugs in suspension
TLDR
An equation relating the rate of release of solid drugs suspended in ointment bases into perfect sinks is derived and the final expression is found to be surprisingly simple and convenient.About:
This article is published in Journal of Pharmaceutical Sciences.The article was published on 1961-10-01. It has received 2031 citations till now. The article focuses on the topics: Ointment Bases.read more
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Mechanistic analysis of drug release from theophylline pellets coated by films containing pectin, chitosan and Eudragit RS.
Alireza Ghaffari,Mohammad Reza Avadi,Hamid Moghimi,Mahvash Oskoui,Khosrow Bayati,Morteza Rafiee-Tehrani +5 more
TL;DR: In this paper, the authors obtained detailed information on the mechanism of drug release from mixed-film of pectin-chitosan/Eudragit RS, which contained 60% theophylline and 40% microcrystalline cellulose by extrusion-spheronization method.
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Swelling controlled release of drug in spherical polymer-penetrant systems
Jenn-Sen Lin,Yu-Lin Peng +1 more
TL;DR: In this paper, the authors address problems of moving boundaries that involve mass diffusion in a spherical swelling polymer-penetrant system with a controlled release of drug and show that the velocity and rate decrease over a short period, and then increase again as the penetrant front proceeds to the sphere center.
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Release study of alfuzosin hydrochloride loaded to novel hydrogel P(HEMA‐co‐AA)
TL;DR: Mohapatra et al. as discussed by the authors used macroporous copolymer 2-hydroxy ethyl methacrylate (HEMA) with acrylic acid (AA) in the presence of N,N′-methylene-bis-acrylamide as crosslinker and benzoyl peroxide as initiator.
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Recent advances of pharmaceutical crystallization theories
TL;DR: In this paper, the perturbed-chain statistical associating fluid theory (PC-SAFT) and a chemical-potential-gradient model are introduced for the analysis of pharmaceutical crystallization.
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Semi-interpenetrating chitosan/ionic liquid polymer networks as electro-responsive biomaterials for potential wound dressings and iontophoretic applications.
TL;DR: Results show that the prepared polycationic semi-interpenetrating copolymer networks (semi-IPN) presented advantageous mechanical, responsive and biological properties that enable them to be potentially employed for the design of new, safer, and advanced stimuli-responsive biomaterials for several biomedical applications such as haemostatic and wound healing dressings and iontophoretic patches.