Journal ArticleDOI
Rate of release of medicaments from ointment bases containing drugs in suspension
TLDR
An equation relating the rate of release of solid drugs suspended in ointment bases into perfect sinks is derived and the final expression is found to be surprisingly simple and convenient.About:
This article is published in Journal of Pharmaceutical Sciences.The article was published on 1961-10-01. It has received 2031 citations till now. The article focuses on the topics: Ointment Bases.read more
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Mechanisms of Isoniazid Release from Poly(d,I-lactide-co-glycolide) Matrices Prepared by Dry-Mixing and Low Density Polymeric Foam Methods
Yung-Yueh Hsu,Joseph D. Gresser,Richard R. Stewart,Debra J. Trantolo,Charles M. Lyons,Girard A. Simons,P.R.J. Gangadharam,Donald L. Wise +7 more
TL;DR: The release mechanisms of a small molecular drug from biodegradable poly(d,l-lactide-co-glycolide) cylindrical matrices were investigated and Isoniazid (INH), one of the most effective drugs against tuberculosis (TB), was selected as the model drug.
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Development and characterization of mucoadhesive patches of salbutamol sulfate for unidirectional buccal drug delivery
TL;DR: Stability studies indicated that there was no change in the chemical and physical characteristics during the test period of 6 months and the surface pH of all patches approached neutral.
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pH-sensitive fluorescent hepatocyte-targeting multilayer polyelectrolyte hollow microspheres as a smart drug delivery system.
Xubo Zhao,Peng Liu +1 more
TL;DR: MTT assays revealed that doxorubicin (a water-insoluble anticancer drug)-loaded (CSFITC/HA)4/GC hollow microspheres can specifically target hepatocytes and exhibit favorable cytocompatibility.
Journal ArticleDOI
Folic acid-conjugated temperature and pH dual-responsive yolk/shell microspheres as a drug delivery system
TL;DR: The precise molecular targeting properties produced by the surface folic acid groups and the independent temperature and pH dual-stimulus responsive characteristics from the unique yolk/shell structure offers promise for cancer treatment.
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Drug Release Properties of Polymer Coated Ion-Exchange Resin Complexes: Experimental and Theoretical Evaluation
TL;DR: The mathematical model has captured the phenomena observed during experimental evaluations and the release dynamics from uncoated and coated particles were predicted accurately and can be used for design purposes.