Journal ArticleDOI
Rate of release of medicaments from ointment bases containing drugs in suspension
TLDR
An equation relating the rate of release of solid drugs suspended in ointment bases into perfect sinks is derived and the final expression is found to be surprisingly simple and convenient.About:
This article is published in Journal of Pharmaceutical Sciences.The article was published on 1961-10-01. It has received 2031 citations till now. The article focuses on the topics: Ointment Bases.read more
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The release kinetics of β-carotene nanocapsules/xanthan gum coating and quality changes in fresh-cut melon (cantaloupe).
María L. Zambrano-Zaragoza,David Quintanar-Guerrero,Alicia Del Real,Elizabeth Piñón-Segundo,José Francisco Zambrano-Zaragoza +4 more
TL;DR: It is concluded that incorporating β-carotene nanocapsules into a polysaccharide matrix improves the properties of the coatings, thereby increasing storage time to 21days at 4°C.
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Simultaneous delivery of paclitaxel and erlotinib from dual drug loaded PLGA nanoparticles: Formulation development, thorough optimization and in vitro release
TL;DR: The XRD and DSC results of a physical mixture and PE-NPs together confirmed that there was not any physical or chemical interaction among the drugs and polymer (PLGA), and there was a minimal variation in size and entrapment efficiency of PE-nPs.
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Controlled release technology for anti-angiogenesis treatment of posterior eye diseases: Current status and challenges
TL;DR: The principle mechanisms of polymeric reservoir, polymeric matrix and hydrogel systems, and the design rationales of the existing drug delivery and release systems in preclinical and clinical stages are revealed.
Journal ArticleDOI
Stimuli-responsive, biocompatible hydrogel derived from glycogen and poly(N-isopropylacrylamide) for colon targeted delivery of ornidazole and 5-amino salicylic acid
Priyapratim Patra,Arun Prabhu Rameshbabu,Dipankar Das,Santanu Dhara,Asit Baran Panda,Sagar Pal +5 more
TL;DR: The synthesized hydrogel can load colon targeted drugs, 5-amino salicylic acid (5-ASA) and ornidazole, efficiently and released both drugs in a controlled manner, while ∼96–97% of drugs remained stable after 2 months.
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Recombinant Amphiphilic Protein Micelles for Drug Delivery
TL;DR: The utility of protein nanoparticles to serve as a vehicle for controlled drug delivery and the capacity of drug-loaded protein micelles to limit the in vivo recruitment of neutrophils in response to an inflammatory stimulus is demonstrated.