Journal ArticleDOI
Rate of release of medicaments from ointment bases containing drugs in suspension
TLDR
An equation relating the rate of release of solid drugs suspended in ointment bases into perfect sinks is derived and the final expression is found to be surprisingly simple and convenient.About:
This article is published in Journal of Pharmaceutical Sciences.The article was published on 1961-10-01. It has received 2031 citations till now. The article focuses on the topics: Ointment Bases.read more
Citations
More filters
Journal ArticleDOI
Application of the Higuchi model for drug release from dispersed matrices to particles of general shape
M. Regina Brophy,P. B. Deasy +1 more
TL;DR: An equation has been derived which describes the short time behaviour of the release of a dispersed drug from a homogeneous matrix of general shape using the pseudo-steady-state approximation of Higuchi and it has been used successfully to describe the experimentally observed release in vitro of Sulphamethizole.
Journal ArticleDOI
Dextrin/poly (HEMA): pH responsive porous hydrogel for controlled release of ciprofloxacin
Dipankar Das,Sagar Pal +1 more
TL;DR: An oral route administration for ciprofloxacin hydrochloride delivery using dextrin and poly (2-hydroxyethyl methylacrylate) based crosslinked hydrogel (c-Dxt/pHEMA) is reported, which is expected to be a promising matrix for cIProfl Oxacin carrier and shows excellent physical stability as carrier up to 3 months.
Journal ArticleDOI
Release of chlorpheniramine maleate from fatty acid ester matrix disks prepared by melt-extrusion.
TL;DR: The release of the drug into distilled water, pH 1·2 buffer, and pH 7·5 buffer showed the expected square root of time dependence and an increase in the fatty acid ester hydrophilic‐lipophilic balance (HLB) resulted in a 10‐fold increase inthe drug release rate.
Journal Article
Liposomal gel with chloramphenicol: characterisation and in vitro release.
TL;DR: In vitro release studies of liposomes incorporated in the gel have shown a prolonged release of entrapped chloramphenicol compared to control gel, and storage stability studies have proven the ability of the Carbopol 974P NF gel to preserve the original size distribution of incorporated liposome.
Journal ArticleDOI
Preparation and Physicochemical Characterization of Eudragit ® RL100 Nanosuspension with potential for Ocular Delivery of Sulfacetamide
TL;DR: In this paper, a formulation of sulfacetamide in Eudragit® RL100 nanosuspension could be used as potential delivery system for treating ocular bacterial infections.