Journal ArticleDOI
Rate of release of medicaments from ointment bases containing drugs in suspension
TLDR
An equation relating the rate of release of solid drugs suspended in ointment bases into perfect sinks is derived and the final expression is found to be surprisingly simple and convenient.About:
This article is published in Journal of Pharmaceutical Sciences.The article was published on 1961-10-01. It has received 2031 citations till now. The article focuses on the topics: Ointment Bases.read more
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Book ChapterDOI
Polymeric and lipid-based systems for controlled drug release: an engineering point of view
Anna Angela Barba,Sabrina Bochicchio,Annalisa Dalmoro,Diego Caccavo,Sara Cascone,Gaetano Lamberti +5 more
TL;DR: The most common techniques to produce and to characterize systems for controlled drug release are reviewed, giving particular emphasis to the fundamentals of the production processes and to the possibility to describe mathematically the phenomena involved in drug release.
Journal ArticleDOI
Application of mesoporous silica materials for the immobilization of polyphenol oxidase
Paula Corell Escuin,Alfonso E. Garcia-Bennett,José V. Ros-Lis,Angel Argüelles Foix,Ana Andrés +4 more
TL;DR: The ability of a number of mesoporous silica materials to immobilize polyphenol oxidase (PPO) at different pH has been tested and pore size and volume are the structural characteristics with higher influence on the PPO immobilization.
Journal ArticleDOI
Synthesis of Multifunctional Fe3O4@mSiO2@Au Core–Shell Nanocomposites for pH-Responsive Drug Delivery
TL;DR: In association with the magnetic target, the multifunctional nanocomposite shows the potential application for some low-pH tissue-targeted therapy, such as for inflammation and tumors.
Journal ArticleDOI
A pH‐responsive drug release system based on doxorubicin conjugated amphiphilic polymer coated quantum dots for tumor cell targeting and tracking
TL;DR: The targeting imaging and pH-responsive drug release system could target the tumor cells and fluoresce quantum dots sensitively due to the conjugation of VEGF, and enabled pH-controlled-activation of the DOX.
Journal ArticleDOI
Layered reactive barrier films
TL;DR: In this article, a layered reactive barrier membrane is constructed to test the theory that the lag time of a barrier film can be dramatically increased by the addition of scavengers which consume solute before it crosses the barrier.