Journal ArticleDOI
Rate of release of medicaments from ointment bases containing drugs in suspension
TLDR
An equation relating the rate of release of solid drugs suspended in ointment bases into perfect sinks is derived and the final expression is found to be surprisingly simple and convenient.About:
This article is published in Journal of Pharmaceutical Sciences.The article was published on 1961-10-01. It has received 2031 citations till now. The article focuses on the topics: Ointment Bases.read more
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Evaluation of matrix type mucoadhesive tablets containing indomethacin for buccal application
TL;DR: The matrix type mucoadhesive tablet has good potential as a preparation for the treatment of pain due to oral aphtha.
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Development and optimization of metoprolol succinate gastroretentive drug delivery system.
TL;DR: The release profile of the optimized batch MS01 fitted first-order kinetics indicated non-Fickian diffusion or anomalous transport by diffusion and swelling, indicating improved drug bioavailability.
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A QSPR study of drug release from an arabinoxylan using ab initio optimization and neural networks
Jamshed Akbar,Mohammad S. Iqbal,Muhammad Taimoor Chaudhary,Tallat Yasin,Shazma Massey,Shazma Massey +5 more
TL;DR: In this article, a QSPR study on release of pharmacologically diverse drugs from a biocompatible matrix, arabinoxylan, by use of ab initio structure optimization and neural networks is reported.
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diffusion of a dispersed solute in a polymeric matrix
TL;DR: A theoretical model for the diffusion study of a molecule in suspension in a continuous medium is presented in this article, which provides a realistic representation of the release by diffusion of a drug in a polymeric matrix at a concentration C 0 above its solubility C s in the medium, in the case where the molecule diffuses into the receptor.
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Hydrophilic modification of silicone elastomer films: thermal, mechanical and theophylline permeability properties.
TL;DR: Results showed that blending increases significantly the overall water uptake of the films and, at the same time, has a limited detrimental effect on their mechanical properties, while end-linked films loaded with theophylline exhibited better rate-controlling properties in vitro, due to better dispersion of the sorbed water.