Journal ArticleDOI
Rate of release of medicaments from ointment bases containing drugs in suspension
TLDR
An equation relating the rate of release of solid drugs suspended in ointment bases into perfect sinks is derived and the final expression is found to be surprisingly simple and convenient.About:
This article is published in Journal of Pharmaceutical Sciences.The article was published on 1961-10-01. It has received 2031 citations till now. The article focuses on the topics: Ointment Bases.read more
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Controlled drug release from hydrogel-based matrices: Experiments and modeling.
TL;DR: In this work, the behavior of hydrogel-based matrices has been investigated by means of several experimental techniques and then all the observed features were mathematically described using a physical model, defined and recently improved by the research group.
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Bone repair: new developments in growth factor delivery systems and their mathematical modeling.
TL;DR: This review first summarizes the process of endochondral bone healing and the major cytokines involved, and reviews the latest GFDSs, with their combinations of organic, inorganic, natural and synthetic biomaterials, the kinetics of GF release and their biological effects.
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Development and evaluation of xanthan gum-facilitated ethyl cellulose microsponges for controlled percutaneous delivery of diclofenac sodium
TL;DR: The microsponge system obtained at the lowest drug/polymer ratio could be useful for controlled release of diclofenac sodium to the skin and was considered most suitable for controlled drug delivery application.
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Topical liposomal gel of tretinoin for the treatment of acne: research and clinical implications.
TL;DR: Potential utility of commercialization of liposomal TRE gel in the treatment of acne is underscored and significant enhancement in drug efficacy is demonstrated.
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Physicochemical Characterization of Hexetidine-Impregnated Endotracheal Tube Poly(vinyl Chloride) and Resistance to Adherence of Respiratory Bacterial Pathogens
TL;DR: ET PVC containing 1% (w/w) hexetidine offered an appropriate balance between suitable physicochemical properties and resistance to microbial adherence and may offer an approach with which to reduce the incidence of ventilator-associated pneumonia.