Journal ArticleDOI
Rate of release of medicaments from ointment bases containing drugs in suspension
TLDR
An equation relating the rate of release of solid drugs suspended in ointment bases into perfect sinks is derived and the final expression is found to be surprisingly simple and convenient.About:
This article is published in Journal of Pharmaceutical Sciences.The article was published on 1961-10-01. It has received 2031 citations till now. The article focuses on the topics: Ointment Bases.read more
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Modeling of degradation and drug release from a biodegradable stent coating.
TL;DR: A simultaneous transport-reaction model predicting the degradation and release of the drug Everolimus from a polylactic acid (PLA) based stent coating is presented and can be used as a tool for predicting drug delivery from other coating configurations designed using the same polymer-drug combination.
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"Smart" alginate-hydroxypropylcellulose microbeads for controlled release of heparin.
Anna Karewicz,Katarzyna Zasada,Krzysztof Szczubiałka,Szczepan Zapotoczny,Radosław Lach,Maria Nowakowska +5 more
TL;DR: "Smart" (thermosensitive) alginate-hydroxypropylcellulose (Alg/HPC) microbeads for controlled release of heparin were synthesized and the release profiles at various temperatures and for various alginates and HPC compositions were measured.
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Mathematical modeling of drug release from lipid dosage forms.
TL;DR: An overview on the current state of the art of mathematical modeling of drug release from this type of advanced drug delivery systems for lipid dosage forms is given, considering diffusional mass transport, potentially limited drug solubility and the leaching of other, water-soluble excipients into the surrounding bulk fluid.
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In-vitro release study of hydrophobic drug using electrospun cross-linked gelatin nanofibers
TL;DR: Good compatibility of hydrophobic drug in gelatin nanofibers with promising controlled drug release patterns by varying crosslinking time and pH of release medium is illustrated.
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Implantable Drug Delivery Systems: An Overview
TL;DR: Combination products constructed using implantable technology offer revolutionary opportunities to address unmet medical needs related to dosing, meeting requirements for on-demand pulsatile or adjustable continuous administration for extended periods.